| Full name: coiled-coil domain containing 140 | Alias Symbol: FLJ32447 | ||
| Type: protein-coding gene | Cytoband: 2q36.1 | ||
| Entrez ID: 151278 | HGNC ID: HGNC:26514 | Ensembl Gene: ENSG00000163081 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC140:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC140 | 151278 | 1553485_at | 0.0435 | 0.9177 | |
| GSE26886 | CCDC140 | 151278 | 1553485_at | 0.1589 | 0.2448 | |
| GSE45670 | CCDC140 | 151278 | 1553485_at | -0.0269 | 0.8042 | |
| GSE53622 | CCDC140 | 151278 | 48524 | 0.1041 | 0.5613 | |
| GSE53624 | CCDC140 | 151278 | 48524 | 0.8617 | 0.0000 | |
| GSE63941 | CCDC140 | 151278 | 1553485_at | 0.4521 | 0.0385 | |
| GSE77861 | CCDC140 | 151278 | 1553485_at | -0.0176 | 0.9102 | |
| TCGA | CCDC140 | 151278 | RNAseq | 2.9015 | 0.0389 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CCDC140 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC140:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC140 | 151278 | 2 | 13 | 15 | |
| GSE20123 | CCDC140 | 151278 | 2 | 13 | 15 | |
| GSE43470 | CCDC140 | 151278 | 0 | 7 | 36 | |
| GSE46452 | CCDC140 | 151278 | 0 | 5 | 54 | |
| GSE47630 | CCDC140 | 151278 | 4 | 5 | 31 | |
| GSE54993 | CCDC140 | 151278 | 1 | 2 | 67 | |
| GSE54994 | CCDC140 | 151278 | 7 | 10 | 36 | |
| GSE60625 | CCDC140 | 151278 | 3 | 0 | 8 | |
| GSE74703 | CCDC140 | 151278 | 0 | 6 | 30 | |
| GSE74704 | CCDC140 | 151278 | 2 | 7 | 11 | |
| TCGA | CCDC140 | 151278 | 13 | 27 | 56 |
Total number of gains: 34; Total number of losses: 95; Total Number of normals: 359.
Somatic mutations of CCDC140:
Generating mutation plots.
Highly correlated genes for CCDC140:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC140 | C14orf178 | 0.721662 | 3 | 0 | 3 |
| CCDC140 | UCN3 | 0.700638 | 4 | 0 | 3 |
| CCDC140 | AK8 | 0.66913 | 3 | 0 | 3 |
| CCDC140 | MYCBPAP | 0.66539 | 3 | 0 | 3 |
| CCDC140 | CACNA1F | 0.660339 | 3 | 0 | 3 |
| CCDC140 | CACNG4 | 0.64998 | 3 | 0 | 3 |
| CCDC140 | USP2-AS1 | 0.649733 | 3 | 0 | 3 |
| CCDC140 | AMBN | 0.638542 | 3 | 0 | 3 |
| CCDC140 | CASC11 | 0.630522 | 3 | 0 | 3 |
| CCDC140 | RANBP3L | 0.626534 | 3 | 0 | 3 |
| CCDC140 | ATCAY | 0.626307 | 4 | 0 | 4 |
| CCDC140 | GLRA2 | 0.625829 | 4 | 0 | 4 |
| CCDC140 | GATA1 | 0.613974 | 4 | 0 | 4 |
| CCDC140 | PANX2 | 0.611016 | 3 | 0 | 3 |
| CCDC140 | GPR135 | 0.604887 | 3 | 0 | 3 |
| CCDC140 | SLC5A2 | 0.594765 | 3 | 0 | 3 |
| CCDC140 | POM121L12 | 0.592851 | 3 | 0 | 3 |
| CCDC140 | VWA3A | 0.587862 | 4 | 0 | 3 |
| CCDC140 | GSC | 0.581985 | 4 | 0 | 3 |
| CCDC140 | GJD2 | 0.561104 | 3 | 0 | 3 |
For details and further investigation, click here
