GLRA2

 

Full name: glycine receptor alpha 2 Alias Symbol: 
Type: protein-coding gene Cytoband: Xp22.2
Entrez ID: 2742 HGNC ID: HGNC:4327 Ensembl Gene: ENSG00000101958 OMIM ID: 305990
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of GLRA2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GLRA2 2742 207462_at 0.0021 0.9955
GSE20347 GLRA2 2742 207462_at 0.1087 0.0757
GSE23400 GLRA2 2742 207462_at -0.0106 0.7778
GSE26886 GLRA2 2742 207462_at 0.2373 0.0471
GSE29001 GLRA2 2742 207462_at -0.1609 0.1367
GSE38129 GLRA2 2742 207462_at 0.0577 0.4451
GSE45670 GLRA2 2742 207462_at 0.1789 0.0176
GSE53622 GLRA2 2742 58254 -0.0759 0.6731
GSE53624 GLRA2 2742 58254 0.3054 0.0017
GSE63941 GLRA2 2742 207462_at 0.3393 0.1118
GSE77861 GLRA2 2742 207462_at -0.0408 0.6994
SRP133303 GLRA2 2742 RNAseq -0.7415 0.0062
TCGA GLRA2 2742 RNAseq 1.1341 0.3611

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by GLRA2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of GLRA2:

 

No record found for this gene.

 

Somatic mutations of GLRA2:

 

Generating mutation plots.

 

Highly correlated genes for GLRA2:

 

Showing top 20/400 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GLRA2GSX10.748806404
GLRA2ROPN1L0.745193303
GLRA2DPYSL50.741366303
GLRA2CC2D2B0.72292303
GLRA2UMOD0.705751303
GLRA2CCDC1510.705414303
GLRA2ABHD10.698841303
GLRA2TAL20.674234303
GLRA2OR8D20.668453303
GLRA2ZFHX4-AS10.667258303
GLRA2ASB120.666343303
GLRA2TCTE30.6522303
GLRA2PLA2G2E0.648673403
GLRA2MUC130.639997303
GLRA2CACNG40.634996706
GLRA2C20orf2030.63278303
GLRA2PANX20.630721403
GLRA2SCGB2B20.629721303
GLRA2LAMA10.629598404
GLRA2AQP100.629336403

For details and further investigation, click here