| Full name: ameloblastin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 258 | HGNC ID: HGNC:452 | Ensembl Gene: ENSG00000178522 | OMIM ID: 601259 |
| Drug and gene relationship at DGIdb | |||
Expression of AMBN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMBN | 258 | 221114_at | 0.0087 | 0.9829 | |
| GSE20347 | AMBN | 258 | 221114_at | -0.0734 | 0.3926 | |
| GSE23400 | AMBN | 258 | 221114_at | -0.1702 | 0.0001 | |
| GSE26886 | AMBN | 258 | 221114_at | -0.0033 | 0.9859 | |
| GSE29001 | AMBN | 258 | 221114_at | -0.1605 | 0.3543 | |
| GSE38129 | AMBN | 258 | 221114_at | -0.1266 | 0.0833 | |
| GSE45670 | AMBN | 258 | 221114_at | 0.1364 | 0.1293 | |
| GSE53622 | AMBN | 258 | 95924 | 0.3833 | 0.0188 | |
| GSE53624 | AMBN | 258 | 95924 | 0.3291 | 0.0013 | |
| GSE63941 | AMBN | 258 | 221114_at | 0.1820 | 0.2577 | |
| GSE77861 | AMBN | 258 | 221114_at | -0.0371 | 0.7991 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AMBN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMBN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMBN | 258 | 0 | 11 | 19 | |
| GSE20123 | AMBN | 258 | 0 | 11 | 19 | |
| GSE43470 | AMBN | 258 | 0 | 13 | 30 | |
| GSE46452 | AMBN | 258 | 2 | 35 | 22 | |
| GSE47630 | AMBN | 258 | 1 | 19 | 20 | |
| GSE54993 | AMBN | 258 | 7 | 0 | 63 | |
| GSE54994 | AMBN | 258 | 1 | 9 | 43 | |
| GSE60625 | AMBN | 258 | 0 | 0 | 11 | |
| GSE74703 | AMBN | 258 | 0 | 11 | 25 | |
| GSE74704 | AMBN | 258 | 0 | 6 | 14 | |
| TCGA | AMBN | 258 | 16 | 28 | 52 |
Total number of gains: 27; Total number of losses: 143; Total Number of normals: 318.
Somatic mutations of AMBN:
Generating mutation plots.
Highly correlated genes for AMBN:
Showing top 20/1076 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMBN | RABEP2 | 0.759279 | 4 | 0 | 4 |
| AMBN | KRT38 | 0.729211 | 5 | 0 | 5 |
| AMBN | GRIN1 | 0.725976 | 4 | 0 | 4 |
| AMBN | RAI1 | 0.717402 | 4 | 0 | 4 |
| AMBN | MTAP | 0.711533 | 4 | 0 | 4 |
| AMBN | NAALADL1 | 0.709771 | 3 | 0 | 3 |
| AMBN | TMEM169 | 0.70378 | 3 | 0 | 3 |
| AMBN | PHF7 | 0.700865 | 4 | 0 | 4 |
| AMBN | TNFSF11 | 0.699368 | 7 | 0 | 7 |
| AMBN | OLFM1 | 0.693093 | 3 | 0 | 3 |
| AMBN | GJB4 | 0.687803 | 9 | 0 | 9 |
| AMBN | GPR31 | 0.687029 | 5 | 0 | 4 |
| AMBN | ECE2 | 0.685456 | 4 | 0 | 4 |
| AMBN | MYO1A | 0.682439 | 5 | 0 | 5 |
| AMBN | MMP24 | 0.682218 | 5 | 0 | 5 |
| AMBN | C8A | 0.681444 | 4 | 0 | 4 |
| AMBN | SLC17A1 | 0.680933 | 5 | 0 | 4 |
| AMBN | SSUH2 | 0.680879 | 4 | 0 | 4 |
| AMBN | KDM5C | 0.67858 | 3 | 0 | 3 |
| AMBN | SCNN1G | 0.676024 | 5 | 0 | 4 |
For details and further investigation, click here
