| Full name: urocortin 3 | Alias Symbol: UCNIII|SPC | ||
| Type: protein-coding gene | Cytoband: 10p15.1 | ||
| Entrez ID: 114131 | HGNC ID: HGNC:17781 | Ensembl Gene: ENSG00000178473 | OMIM ID: 605901 |
| Drug and gene relationship at DGIdb | |||
Expression of UCN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UCN3 | 114131 | 1552676_at | 0.0663 | 0.7852 | |
| GSE26886 | UCN3 | 114131 | 1552676_at | -0.0084 | 0.9682 | |
| GSE45670 | UCN3 | 114131 | 1552676_at | 0.2645 | 0.0005 | |
| GSE53622 | UCN3 | 114131 | 80981 | 0.0300 | 0.5259 | |
| GSE53624 | UCN3 | 114131 | 80981 | 0.1531 | 0.0971 | |
| GSE63941 | UCN3 | 114131 | 1552676_at | 0.6216 | 0.0008 | |
| GSE77861 | UCN3 | 114131 | 1552676_at | -0.0064 | 0.9677 | |
| GSE97050 | UCN3 | 114131 | A_33_P3241369 | -0.0505 | 0.8283 | |
| TCGA | UCN3 | 114131 | RNAseq | -1.8839 | 0.3481 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UCN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UCN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UCN3 | 114131 | 6 | 7 | 17 | |
| GSE20123 | UCN3 | 114131 | 6 | 6 | 18 | |
| GSE43470 | UCN3 | 114131 | 4 | 6 | 33 | |
| GSE46452 | UCN3 | 114131 | 2 | 14 | 43 | |
| GSE47630 | UCN3 | 114131 | 6 | 14 | 20 | |
| GSE54993 | UCN3 | 114131 | 11 | 0 | 59 | |
| GSE54994 | UCN3 | 114131 | 5 | 10 | 38 | |
| GSE60625 | UCN3 | 114131 | 0 | 0 | 11 | |
| GSE74703 | UCN3 | 114131 | 3 | 4 | 29 | |
| GSE74704 | UCN3 | 114131 | 1 | 5 | 14 | |
| TCGA | UCN3 | 114131 | 20 | 24 | 52 |
Total number of gains: 64; Total number of losses: 90; Total Number of normals: 334.
Somatic mutations of UCN3:
Generating mutation plots.
Highly correlated genes for UCN3:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UCN3 | CACNG4 | 0.778543 | 3 | 0 | 3 |
| UCN3 | PRB1 | 0.741278 | 3 | 0 | 3 |
| UCN3 | CCDC140 | 0.700638 | 4 | 0 | 3 |
| UCN3 | PNPLA2 | 0.691768 | 3 | 0 | 3 |
| UCN3 | MIOX | 0.681296 | 3 | 0 | 3 |
| UCN3 | TMEM151A | 0.674305 | 4 | 0 | 3 |
| UCN3 | DIRAS1 | 0.674278 | 3 | 0 | 3 |
| UCN3 | SLC34A3 | 0.665585 | 3 | 0 | 3 |
| UCN3 | CUL7 | 0.660178 | 3 | 0 | 3 |
| UCN3 | PRAMEF11 | 0.656391 | 4 | 0 | 3 |
| UCN3 | E2F4 | 0.648024 | 3 | 0 | 3 |
| UCN3 | VSX1 | 0.647333 | 3 | 0 | 3 |
| UCN3 | IL1F10 | 0.643738 | 3 | 0 | 3 |
| UCN3 | TSGA13 | 0.641481 | 4 | 0 | 4 |
| UCN3 | GPR6 | 0.641012 | 5 | 0 | 5 |
| UCN3 | PNLIPRP1 | 0.639318 | 5 | 0 | 4 |
| UCN3 | HIPK1-AS1 | 0.638385 | 3 | 0 | 3 |
| UCN3 | TSACC | 0.635995 | 4 | 0 | 3 |
| UCN3 | PRKG2 | 0.634824 | 3 | 0 | 3 |
| UCN3 | LINC00642 | 0.633683 | 3 | 0 | 3 |
For details and further investigation, click here
