| Full name: gap junction protein delta 2 | Alias Symbol: CX36 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 57369 | HGNC ID: HGNC:19154 | Ensembl Gene: ENSG00000159248 | OMIM ID: 607058 |
| Drug and gene relationship at DGIdb | |||
GJD2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04540 | Gap junction |
Expression of GJD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GJD2 | 57369 | 221407_at | -0.1047 | 0.6188 | |
| GSE20347 | GJD2 | 57369 | 221407_at | 0.0082 | 0.9414 | |
| GSE23400 | GJD2 | 57369 | 221407_at | -0.0888 | 0.0668 | |
| GSE26886 | GJD2 | 57369 | 221407_at | 0.0448 | 0.7696 | |
| GSE29001 | GJD2 | 57369 | 221407_at | -0.1703 | 0.2103 | |
| GSE38129 | GJD2 | 57369 | 221407_at | -0.0907 | 0.4756 | |
| GSE45670 | GJD2 | 57369 | 221407_at | -0.0984 | 0.3751 | |
| GSE53622 | GJD2 | 57369 | 142992 | -0.0158 | 0.9198 | |
| GSE53624 | GJD2 | 57369 | 142992 | 0.2808 | 0.0051 | |
| GSE63941 | GJD2 | 57369 | 221407_at | 0.0624 | 0.7109 | |
| GSE77861 | GJD2 | 57369 | 221407_at | -0.0348 | 0.7270 | |
| TCGA | GJD2 | 57369 | RNAseq | 0.2583 | 0.8876 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GJD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GJD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GJD2 | 57369 | 3 | 6 | 21 | |
| GSE20123 | GJD2 | 57369 | 3 | 6 | 21 | |
| GSE43470 | GJD2 | 57369 | 4 | 4 | 35 | |
| GSE46452 | GJD2 | 57369 | 3 | 7 | 49 | |
| GSE47630 | GJD2 | 57369 | 8 | 11 | 21 | |
| GSE54993 | GJD2 | 57369 | 4 | 6 | 60 | |
| GSE54994 | GJD2 | 57369 | 5 | 8 | 40 | |
| GSE60625 | GJD2 | 57369 | 4 | 0 | 7 | |
| GSE74703 | GJD2 | 57369 | 4 | 3 | 29 | |
| GSE74704 | GJD2 | 57369 | 2 | 5 | 13 | |
| TCGA | GJD2 | 57369 | 13 | 18 | 65 |
Total number of gains: 53; Total number of losses: 74; Total Number of normals: 361.
Somatic mutations of GJD2:
Generating mutation plots.
Highly correlated genes for GJD2:
Showing top 20/1039 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GJD2 | CCDC116 | 0.700266 | 3 | 0 | 3 |
| GJD2 | ZNF460 | 0.693383 | 4 | 0 | 4 |
| GJD2 | NUDT7 | 0.693182 | 4 | 0 | 4 |
| GJD2 | CAPN11 | 0.690589 | 4 | 0 | 4 |
| GJD2 | GPR21 | 0.688585 | 4 | 0 | 4 |
| GJD2 | GPR12 | 0.687966 | 5 | 0 | 5 |
| GJD2 | NXPE4 | 0.687513 | 5 | 0 | 5 |
| GJD2 | ACSBG2 | 0.680114 | 6 | 0 | 5 |
| GJD2 | OR10H3 | 0.678083 | 6 | 0 | 5 |
| GJD2 | PAPOLB | 0.677362 | 3 | 0 | 3 |
| GJD2 | OR51B5 | 0.676172 | 3 | 0 | 3 |
| GJD2 | GSX1 | 0.675691 | 3 | 0 | 3 |
| GJD2 | LINC00216 | 0.6743 | 5 | 0 | 5 |
| GJD2 | CEACAM21 | 0.674129 | 4 | 0 | 4 |
| GJD2 | KCNJ10 | 0.672756 | 4 | 0 | 4 |
| GJD2 | HS6ST1 | 0.672268 | 3 | 0 | 3 |
| GJD2 | NFIA-AS2 | 0.67219 | 4 | 0 | 4 |
| GJD2 | KIR2DL2 | 0.672092 | 5 | 0 | 5 |
| GJD2 | FUT9 | 0.669965 | 3 | 0 | 3 |
| GJD2 | CCDC87 | 0.669544 | 4 | 0 | 4 |
For details and further investigation, click here
