| Full name: C-C motif chemokine ligand 24 | Alias Symbol: Ckb-6|MPIF-2|eotaxin-2|MPIF2 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 6369 | HGNC ID: HGNC:10623 | Ensembl Gene: ENSG00000106178 | OMIM ID: 602495 |
| Drug and gene relationship at DGIdb | |||
CCL24 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04062 | Chemokine signaling pathway |
Expression of CCL24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCL24 | 6369 | 221463_at | -0.3860 | 0.2300 | |
| GSE20347 | CCL24 | 6369 | 221463_at | -0.0663 | 0.4716 | |
| GSE23400 | CCL24 | 6369 | 221463_at | -0.2001 | 0.0000 | |
| GSE26886 | CCL24 | 6369 | 221463_at | -0.0969 | 0.5215 | |
| GSE29001 | CCL24 | 6369 | 221463_at | -0.0601 | 0.6731 | |
| GSE38129 | CCL24 | 6369 | 221463_at | -0.1243 | 0.0761 | |
| GSE45670 | CCL24 | 6369 | 221463_at | 0.1294 | 0.2785 | |
| GSE53622 | CCL24 | 6369 | 14036 | 0.0571 | 0.6596 | |
| GSE53624 | CCL24 | 6369 | 14036 | -0.2675 | 0.0008 | |
| GSE63941 | CCL24 | 6369 | 221463_at | -0.0072 | 0.9728 | |
| GSE77861 | CCL24 | 6369 | 221463_at | -0.1380 | 0.4318 | |
| GSE97050 | CCL24 | 6369 | A_23_P215491 | 0.9298 | 0.1728 | |
| SRP064894 | CCL24 | 6369 | RNAseq | 0.9058 | 0.0034 | |
| SRP133303 | CCL24 | 6369 | RNAseq | 0.7619 | 0.0005 | |
| SRP159526 | CCL24 | 6369 | RNAseq | 0.7387 | 0.2609 | |
| SRP193095 | CCL24 | 6369 | RNAseq | 0.1974 | 0.4662 | |
| SRP219564 | CCL24 | 6369 | RNAseq | 1.4707 | 0.0031 | |
| TCGA | CCL24 | 6369 | RNAseq | 1.8483 | 0.0024 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CCL24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCL24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCL24 | 6369 | 14 | 1 | 15 | |
| GSE20123 | CCL24 | 6369 | 14 | 1 | 15 | |
| GSE43470 | CCL24 | 6369 | 3 | 2 | 38 | |
| GSE46452 | CCL24 | 6369 | 12 | 0 | 47 | |
| GSE47630 | CCL24 | 6369 | 7 | 2 | 31 | |
| GSE54993 | CCL24 | 6369 | 2 | 7 | 61 | |
| GSE54994 | CCL24 | 6369 | 14 | 3 | 36 | |
| GSE60625 | CCL24 | 6369 | 0 | 0 | 11 | |
| GSE74703 | CCL24 | 6369 | 3 | 1 | 32 | |
| GSE74704 | CCL24 | 6369 | 8 | 1 | 11 | |
| TCGA | CCL24 | 6369 | 44 | 5 | 47 |
Total number of gains: 121; Total number of losses: 23; Total Number of normals: 344.
Somatic mutations of CCL24:
Generating mutation plots.
Highly correlated genes for CCL24:
Showing top 20/547 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCL24 | SPNS3 | 0.757543 | 3 | 0 | 3 |
| CCL24 | ULBP3 | 0.752853 | 3 | 0 | 3 |
| CCL24 | CARS-AS1 | 0.752729 | 3 | 0 | 3 |
| CCL24 | LINC00922 | 0.750827 | 3 | 0 | 3 |
| CCL24 | IGLL1 | 0.743788 | 4 | 0 | 4 |
| CCL24 | IGH | 0.742987 | 4 | 0 | 4 |
| CCL24 | LAMA5-AS1 | 0.737614 | 3 | 0 | 3 |
| CCL24 | LRRC29 | 0.734512 | 3 | 0 | 3 |
| CCL24 | ADAM12 | 0.728031 | 3 | 0 | 3 |
| CCL24 | VGF | 0.722819 | 3 | 0 | 3 |
| CCL24 | MYCN | 0.704531 | 3 | 0 | 3 |
| CCL24 | FAM207A | 0.704347 | 3 | 0 | 3 |
| CCL24 | CDHR5 | 0.692822 | 5 | 0 | 4 |
| CCL24 | IQCJ-SCHIP1-AS1 | 0.691094 | 3 | 0 | 3 |
| CCL24 | DDX4 | 0.690512 | 4 | 0 | 4 |
| CCL24 | NLRP6 | 0.690279 | 3 | 0 | 3 |
| CCL24 | CACNG5 | 0.685009 | 4 | 0 | 4 |
| CCL24 | SARDH | 0.681103 | 4 | 0 | 4 |
| CCL24 | RNF31 | 0.680103 | 3 | 0 | 3 |
| CCL24 | SLC6A7 | 0.67897 | 4 | 0 | 4 |
For details and further investigation, click here
