| Full name: solute carrier family 6 member 7 | Alias Symbol: PROT | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 6534 | HGNC ID: HGNC:11054 | Ensembl Gene: ENSG00000011083 | OMIM ID: 606205 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC6A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A7 | 6534 | 208494_at | 0.0636 | 0.7899 | |
| GSE20347 | SLC6A7 | 6534 | 208494_at | -0.0719 | 0.2880 | |
| GSE23400 | SLC6A7 | 6534 | 208494_at | -0.0741 | 0.0313 | |
| GSE26886 | SLC6A7 | 6534 | 208494_at | 0.0726 | 0.5581 | |
| GSE29001 | SLC6A7 | 6534 | 208494_at | -0.1741 | 0.2233 | |
| GSE38129 | SLC6A7 | 6534 | 208494_at | -0.0621 | 0.3306 | |
| GSE45670 | SLC6A7 | 6534 | 208494_at | -0.0854 | 0.3579 | |
| GSE53622 | SLC6A7 | 6534 | 12600 | 0.5394 | 0.0000 | |
| GSE53624 | SLC6A7 | 6534 | 12600 | 1.5199 | 0.0000 | |
| GSE63941 | SLC6A7 | 6534 | 208494_at | -0.1023 | 0.4851 | |
| GSE77861 | SLC6A7 | 6534 | 208494_at | -0.2579 | 0.0301 | |
| TCGA | SLC6A7 | 6534 | RNAseq | 2.7904 | 0.0015 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SLC6A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A7 | 6534 | 1 | 12 | 17 | |
| GSE20123 | SLC6A7 | 6534 | 1 | 12 | 17 | |
| GSE43470 | SLC6A7 | 6534 | 1 | 10 | 32 | |
| GSE46452 | SLC6A7 | 6534 | 0 | 27 | 32 | |
| GSE47630 | SLC6A7 | 6534 | 0 | 20 | 20 | |
| GSE54993 | SLC6A7 | 6534 | 9 | 1 | 60 | |
| GSE54994 | SLC6A7 | 6534 | 2 | 15 | 36 | |
| GSE60625 | SLC6A7 | 6534 | 0 | 0 | 11 | |
| GSE74703 | SLC6A7 | 6534 | 1 | 7 | 28 | |
| GSE74704 | SLC6A7 | 6534 | 1 | 7 | 12 | |
| TCGA | SLC6A7 | 6534 | 5 | 38 | 53 |
Total number of gains: 21; Total number of losses: 149; Total Number of normals: 318.
Somatic mutations of SLC6A7:
Generating mutation plots.
Highly correlated genes for SLC6A7:
Showing top 20/458 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A7 | C4BPB | 0.693418 | 4 | 0 | 3 |
| SLC6A7 | CCL24 | 0.67897 | 4 | 0 | 4 |
| SLC6A7 | CEACAM21 | 0.676174 | 6 | 0 | 6 |
| SLC6A7 | PGLYRP1 | 0.669157 | 5 | 0 | 4 |
| SLC6A7 | PRKACG | 0.666996 | 4 | 0 | 3 |
| SLC6A7 | CISH | 0.666853 | 3 | 0 | 3 |
| SLC6A7 | LMAN1L | 0.666642 | 5 | 0 | 5 |
| SLC6A7 | XKR8 | 0.663348 | 3 | 0 | 3 |
| SLC6A7 | MUC8 | 0.663243 | 4 | 0 | 3 |
| SLC6A7 | GALR1 | 0.662167 | 3 | 0 | 3 |
| SLC6A7 | RAMP2 | 0.662042 | 3 | 0 | 3 |
| SLC6A7 | MS4A3 | 0.659736 | 4 | 0 | 3 |
| SLC6A7 | MYH8 | 0.652059 | 4 | 0 | 4 |
| SLC6A7 | HCG9 | 0.649748 | 4 | 0 | 3 |
| SLC6A7 | PRDM14 | 0.64469 | 4 | 0 | 4 |
| SLC6A7 | KRTAP19-3 | 0.644021 | 3 | 0 | 3 |
| SLC6A7 | NEURL1 | 0.643597 | 5 | 0 | 4 |
| SLC6A7 | ACTL6B | 0.642823 | 4 | 0 | 3 |
| SLC6A7 | GRAP2 | 0.642076 | 4 | 0 | 3 |
| SLC6A7 | ABCC8 | 0.641358 | 5 | 0 | 5 |
For details and further investigation, click here
