| Full name: UL16 binding protein 3 | Alias Symbol: RAET1N | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 79465 | HGNC ID: HGNC:14895 | Ensembl Gene: ENSG00000131019 | OMIM ID: 605699 |
| Drug and gene relationship at DGIdb | |||
ULBP3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity |
Expression of ULBP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ULBP3 | 79465 | 231748_at | -0.2802 | 0.3839 | |
| GSE26886 | ULBP3 | 79465 | 231748_at | 0.0792 | 0.3962 | |
| GSE45670 | ULBP3 | 79465 | 231748_at | -0.0678 | 0.5276 | |
| GSE53622 | ULBP3 | 79465 | 7905 | 0.9822 | 0.0000 | |
| GSE53624 | ULBP3 | 79465 | 7905 | 0.2876 | 0.0059 | |
| GSE63941 | ULBP3 | 79465 | 231748_at | 0.4377 | 0.2195 | |
| GSE77861 | ULBP3 | 79465 | 231748_at | -0.2666 | 0.1019 | |
| GSE97050 | ULBP3 | 79465 | A_23_P134100 | 1.2101 | 0.1456 | |
| SRP007169 | ULBP3 | 79465 | RNAseq | 1.1457 | 0.0016 | |
| SRP008496 | ULBP3 | 79465 | RNAseq | 1.0658 | 0.0077 | |
| SRP064894 | ULBP3 | 79465 | RNAseq | 0.8657 | 0.0054 | |
| SRP133303 | ULBP3 | 79465 | RNAseq | 0.9531 | 0.0001 | |
| SRP159526 | ULBP3 | 79465 | RNAseq | 1.0152 | 0.0161 | |
| SRP193095 | ULBP3 | 79465 | RNAseq | 0.3361 | 0.0503 | |
| SRP219564 | ULBP3 | 79465 | RNAseq | 0.1289 | 0.8442 | |
| TCGA | ULBP3 | 79465 | RNAseq | 0.6240 | 0.0001 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ULBP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ULBP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ULBP3 | 79465 | 2 | 4 | 24 | |
| GSE20123 | ULBP3 | 79465 | 2 | 3 | 25 | |
| GSE43470 | ULBP3 | 79465 | 4 | 0 | 39 | |
| GSE46452 | ULBP3 | 79465 | 3 | 10 | 46 | |
| GSE47630 | ULBP3 | 79465 | 9 | 4 | 27 | |
| GSE54993 | ULBP3 | 79465 | 3 | 2 | 65 | |
| GSE54994 | ULBP3 | 79465 | 8 | 8 | 37 | |
| GSE60625 | ULBP3 | 79465 | 0 | 1 | 10 | |
| GSE74703 | ULBP3 | 79465 | 4 | 0 | 32 | |
| GSE74704 | ULBP3 | 79465 | 0 | 1 | 19 | |
| TCGA | ULBP3 | 79465 | 12 | 21 | 63 |
Total number of gains: 47; Total number of losses: 54; Total Number of normals: 387.
Somatic mutations of ULBP3:
Generating mutation plots.
Highly correlated genes for ULBP3:
Showing top 20/54 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ULBP3 | CCL24 | 0.752853 | 3 | 0 | 3 |
| ULBP3 | ACTR5 | 0.752027 | 3 | 0 | 3 |
| ULBP3 | FAM131C | 0.728152 | 3 | 0 | 3 |
| ULBP3 | PTTG2 | 0.695647 | 4 | 0 | 4 |
| ULBP3 | INSL3 | 0.676069 | 3 | 0 | 3 |
| ULBP3 | OPRL1 | 0.657024 | 3 | 0 | 3 |
| ULBP3 | NRG1 | 0.639809 | 5 | 0 | 4 |
| ULBP3 | SMIM24 | 0.63297 | 3 | 0 | 3 |
| ULBP3 | FAM222A-AS1 | 0.628372 | 3 | 0 | 3 |
| ULBP3 | SNHG10 | 0.627499 | 3 | 0 | 3 |
| ULBP3 | NOXA1 | 0.625594 | 3 | 0 | 3 |
| ULBP3 | SNX8 | 0.620939 | 5 | 0 | 3 |
| ULBP3 | TPD52L1 | 0.61343 | 3 | 0 | 3 |
| ULBP3 | ST18 | 0.613369 | 3 | 0 | 3 |
| ULBP3 | NDOR1 | 0.612273 | 4 | 0 | 3 |
| ULBP3 | SLC22A7 | 0.612071 | 3 | 0 | 3 |
| ULBP3 | IQCJ-SCHIP1-AS1 | 0.608544 | 3 | 0 | 3 |
| ULBP3 | CHRNG | 0.604833 | 3 | 0 | 3 |
| ULBP3 | SMAGP | 0.60268 | 4 | 0 | 4 |
| ULBP3 | SPATA21 | 0.596282 | 3 | 0 | 3 |
For details and further investigation, click here
