| Full name: carboxymethylenebutenolidase homolog | Alias Symbol: FLJ23617 | ||
| Type: protein-coding gene | Cytoband: 5p15.2 | ||
| Entrez ID: 134147 | HGNC ID: HGNC:25090 | Ensembl Gene: ENSG00000164237 | OMIM ID: 613379 |
| Drug and gene relationship at DGIdb | |||
Expression of CMBL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CMBL | 134147 | 234981_x_at | 0.3322 | 0.5238 | |
| GSE26886 | CMBL | 134147 | 234981_x_at | 0.4005 | 0.0241 | |
| GSE45670 | CMBL | 134147 | 234981_x_at | 0.2628 | 0.0169 | |
| GSE63941 | CMBL | 134147 | 234981_x_at | -0.3341 | 0.0297 | |
| GSE77861 | CMBL | 134147 | 234981_x_at | 0.6396 | 0.1375 | |
| SRP007169 | CMBL | 134147 | RNAseq | 1.9753 | 0.0039 | |
| SRP008496 | CMBL | 134147 | RNAseq | 2.5447 | 0.0000 | |
| SRP064894 | CMBL | 134147 | RNAseq | 0.5745 | 0.0842 | |
| SRP133303 | CMBL | 134147 | RNAseq | 0.6884 | 0.0484 | |
| SRP159526 | CMBL | 134147 | RNAseq | 1.3252 | 0.0044 | |
| SRP193095 | CMBL | 134147 | RNAseq | -0.3975 | 0.2271 | |
| SRP219564 | CMBL | 134147 | RNAseq | 0.6501 | 0.3580 | |
| TCGA | CMBL | 134147 | RNAseq | -0.4896 | 0.0003 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CMBL expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CMBL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CMBL | 134147 | 12 | 0 | 18 | |
| GSE20123 | CMBL | 134147 | 12 | 0 | 18 | |
| GSE43470 | CMBL | 134147 | 18 | 0 | 25 | |
| GSE46452 | CMBL | 134147 | 6 | 22 | 31 | |
| GSE47630 | CMBL | 134147 | 6 | 11 | 23 | |
| GSE54993 | CMBL | 134147 | 5 | 5 | 60 | |
| GSE54994 | CMBL | 134147 | 29 | 1 | 23 | |
| GSE60625 | CMBL | 134147 | 0 | 0 | 11 | |
| GSE74703 | CMBL | 134147 | 14 | 0 | 22 | |
| GSE74704 | CMBL | 134147 | 11 | 0 | 9 | |
| TCGA | CMBL | 134147 | 58 | 3 | 35 |
Total number of gains: 171; Total number of losses: 42; Total Number of normals: 275.
Somatic mutations of CMBL:
Generating mutation plots.
Highly correlated genes for CMBL:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CMBL | DDX59 | 0.938599 | 4 | 0 | 4 |
| CMBL | ALMS1 | 0.928732 | 3 | 0 | 3 |
| CMBL | ZNF160 | 0.918838 | 5 | 0 | 5 |
| CMBL | CDK13 | 0.914181 | 5 | 0 | 5 |
| CMBL | CCDC152 | 0.913825 | 5 | 0 | 5 |
| CMBL | MZT2B | 0.905461 | 5 | 0 | 5 |
| CMBL | NLN | 0.904385 | 5 | 0 | 5 |
| CMBL | FBXW12 | 0.902963 | 5 | 0 | 5 |
| CMBL | PGF | 0.894602 | 5 | 0 | 5 |
| CMBL | SLC35E1 | 0.891989 | 5 | 0 | 5 |
| CMBL | ZNF721 | 0.884301 | 5 | 0 | 5 |
| CMBL | ZC3H7B | 0.883681 | 3 | 0 | 3 |
| CMBL | C9orf64 | 0.867966 | 5 | 0 | 5 |
| CMBL | GTSE1 | 0.860729 | 4 | 0 | 4 |
| CMBL | DLGAP4 | 0.855367 | 5 | 0 | 5 |
| CMBL | SLC22A3 | 0.847473 | 5 | 0 | 5 |
| CMBL | DIP2A | 0.846213 | 5 | 0 | 5 |
| CMBL | ORAI2 | 0.831945 | 5 | 0 | 5 |
| CMBL | FUT8-AS1 | 0.828269 | 4 | 0 | 4 |
| CMBL | SLC25A16 | 0.826094 | 4 | 0 | 4 |
For details and further investigation, click here
