| Full name: kinesin family member C2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 90990 | HGNC ID: HGNC:29530 | Ensembl Gene: ENSG00000167702 | OMIM ID: 615216 |
| Drug and gene relationship at DGIdb | |||
Expression of KIFC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIFC2 | 90990 | 226792_s_at | 0.4239 | 0.6528 | |
| GSE26886 | KIFC2 | 90990 | 226792_s_at | 0.2073 | 0.3798 | |
| GSE45670 | KIFC2 | 90990 | 226792_s_at | 0.0838 | 0.6555 | |
| GSE53622 | KIFC2 | 90990 | 7629 | 0.4748 | 0.0000 | |
| GSE53624 | KIFC2 | 90990 | 7629 | 0.5496 | 0.0000 | |
| GSE63941 | KIFC2 | 90990 | 226792_s_at | 0.2792 | 0.3838 | |
| GSE77861 | KIFC2 | 90990 | 226792_s_at | -0.0032 | 0.9903 | |
| GSE97050 | KIFC2 | 90990 | A_33_P3414683 | 0.2237 | 0.3333 | |
| SRP007169 | KIFC2 | 90990 | RNAseq | -0.6755 | 0.2315 | |
| SRP008496 | KIFC2 | 90990 | RNAseq | 0.2325 | 0.5794 | |
| SRP064894 | KIFC2 | 90990 | RNAseq | 0.4349 | 0.2265 | |
| SRP133303 | KIFC2 | 90990 | RNAseq | -0.3436 | 0.1090 | |
| SRP159526 | KIFC2 | 90990 | RNAseq | -0.4772 | 0.1699 | |
| SRP193095 | KIFC2 | 90990 | RNAseq | 0.0126 | 0.9509 | |
| SRP219564 | KIFC2 | 90990 | RNAseq | 0.5368 | 0.5311 | |
| TCGA | KIFC2 | 90990 | RNAseq | 0.3043 | 0.0038 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KIFC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIFC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIFC2 | 90990 | 17 | 1 | 12 | |
| GSE20123 | KIFC2 | 90990 | 17 | 1 | 12 | |
| GSE43470 | KIFC2 | 90990 | 16 | 2 | 25 | |
| GSE46452 | KIFC2 | 90990 | 28 | 0 | 31 | |
| GSE47630 | KIFC2 | 90990 | 25 | 1 | 14 | |
| GSE54993 | KIFC2 | 90990 | 0 | 25 | 45 | |
| GSE54994 | KIFC2 | 90990 | 39 | 1 | 13 | |
| GSE60625 | KIFC2 | 90990 | 3 | 4 | 4 | |
| GSE74703 | KIFC2 | 90990 | 14 | 1 | 21 | |
| GSE74704 | KIFC2 | 90990 | 10 | 0 | 10 | |
| TCGA | KIFC2 | 90990 | 63 | 2 | 31 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of KIFC2:
Generating mutation plots.
Highly correlated genes for KIFC2:
Showing top 20/257 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIFC2 | WDPCP | 0.767023 | 3 | 0 | 3 |
| KIFC2 | STX1B | 0.759092 | 4 | 0 | 4 |
| KIFC2 | TBX19 | 0.757945 | 3 | 0 | 3 |
| KIFC2 | TAOK2 | 0.727953 | 7 | 0 | 7 |
| KIFC2 | CDK13 | 0.726073 | 4 | 0 | 4 |
| KIFC2 | MYOZ3 | 0.724244 | 3 | 0 | 3 |
| KIFC2 | GNB3 | 0.722441 | 4 | 0 | 4 |
| KIFC2 | MEGF11 | 0.716439 | 4 | 0 | 4 |
| KIFC2 | GRIPAP1 | 0.710573 | 3 | 0 | 3 |
| KIFC2 | ARHGEF1 | 0.709865 | 4 | 0 | 3 |
| KIFC2 | CIB3 | 0.709143 | 3 | 0 | 3 |
| KIFC2 | NKAIN4 | 0.706886 | 3 | 0 | 3 |
| KIFC2 | PARP10 | 0.702335 | 3 | 0 | 3 |
| KIFC2 | ST8SIA1 | 0.699732 | 3 | 0 | 3 |
| KIFC2 | MS4A18 | 0.695795 | 3 | 0 | 3 |
| KIFC2 | HAP1 | 0.695392 | 4 | 0 | 4 |
| KIFC2 | SLC39A5 | 0.695251 | 3 | 0 | 3 |
| KIFC2 | PSMB11 | 0.692964 | 4 | 0 | 3 |
| KIFC2 | SALL4 | 0.689749 | 3 | 0 | 3 |
| KIFC2 | ZNRF4 | 0.687792 | 3 | 0 | 3 |
For details and further investigation, click here
