| Full name: keratin associated protein 10-12 | Alias Symbol: KRTAP18.12|KAP10.12 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 386685 | HGNC ID: HGNC:20533 | Ensembl Gene: ENSG00000189169 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP10-12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | KRTAP10-12 | 386685 | 118112 | 0.2897 | 0.0335 | |
| GSE53624 | KRTAP10-12 | 386685 | 118112 | -0.0033 | 0.9769 | |
| GSE97050 | KRTAP10-12 | 386685 | A_33_P3357651 | -0.0894 | 0.7835 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP10-12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP10-12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP10-12 | 386685 | 2 | 8 | 20 | |
| GSE20123 | KRTAP10-12 | 386685 | 2 | 8 | 20 | |
| GSE43470 | KRTAP10-12 | 386685 | 0 | 13 | 30 | |
| GSE46452 | KRTAP10-12 | 386685 | 1 | 21 | 37 | |
| GSE47630 | KRTAP10-12 | 386685 | 6 | 17 | 17 | |
| GSE54993 | KRTAP10-12 | 386685 | 8 | 1 | 61 | |
| GSE54994 | KRTAP10-12 | 386685 | 4 | 8 | 41 | |
| GSE60625 | KRTAP10-12 | 386685 | 0 | 0 | 11 | |
| GSE74703 | KRTAP10-12 | 386685 | 0 | 10 | 26 | |
| GSE74704 | KRTAP10-12 | 386685 | 1 | 4 | 15 |
Total number of gains: 24; Total number of losses: 90; Total Number of normals: 278.
Somatic mutations of KRTAP10-12:
Generating mutation plots.
Highly correlated genes for KRTAP10-12:
Showing top 20/314 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP10-12 | KRTAP4-8 | 0.877013 | 3 | 0 | 3 |
| KRTAP10-12 | WDR87 | 0.871439 | 3 | 0 | 3 |
| KRTAP10-12 | SLC26A1 | 0.869704 | 3 | 0 | 3 |
| KRTAP10-12 | TMEM105 | 0.864971 | 3 | 0 | 3 |
| KRTAP10-12 | SYCN | 0.848166 | 3 | 0 | 3 |
| KRTAP10-12 | BTNL2 | 0.847583 | 3 | 0 | 3 |
| KRTAP10-12 | F2RL3 | 0.841445 | 3 | 0 | 3 |
| KRTAP10-12 | SERPINA10 | 0.839971 | 3 | 0 | 3 |
| KRTAP10-12 | FOXE3 | 0.83824 | 3 | 0 | 3 |
| KRTAP10-12 | ST8SIA3 | 0.838111 | 3 | 0 | 3 |
| KRTAP10-12 | DEFB108B | 0.833701 | 3 | 0 | 3 |
| KRTAP10-12 | GHSR | 0.83178 | 3 | 0 | 3 |
| KRTAP10-12 | ZNF763 | 0.830972 | 3 | 0 | 3 |
| KRTAP10-12 | KCNH3 | 0.828694 | 3 | 0 | 3 |
| KRTAP10-12 | SIM1 | 0.828153 | 3 | 0 | 3 |
| KRTAP10-12 | PLA2G2C | 0.827299 | 3 | 0 | 3 |
| KRTAP10-12 | AQP8 | 0.826802 | 3 | 0 | 3 |
| KRTAP10-12 | CLDN9 | 0.826694 | 3 | 0 | 3 |
| KRTAP10-12 | YY2 | 0.826107 | 3 | 0 | 3 |
| KRTAP10-12 | SLC22A31 | 0.82174 | 3 | 0 | 3 |
For details and further investigation, click here
