| Full name: uveal autoantigen with coiled-coil domains and ankyrin repeats | Alias Symbol: FLJ10128|KIAA1561 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 55075 | HGNC ID: HGNC:15947 | Ensembl Gene: ENSG00000137831 | OMIM ID: 612516 |
| Drug and gene relationship at DGIdb | |||
Expression of UACA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UACA | 55075 | 223279_s_at | -1.0920 | 0.0394 | |
| GSE26886 | UACA | 55075 | 236715_x_at | 0.1317 | 0.4309 | |
| GSE45670 | UACA | 55075 | 236715_x_at | 0.1307 | 0.2694 | |
| GSE53622 | UACA | 55075 | 63054 | -0.3915 | 0.0028 | |
| GSE53624 | UACA | 55075 | 63054 | -0.3889 | 0.0077 | |
| GSE63941 | UACA | 55075 | 236715_x_at | -0.7098 | 0.0007 | |
| GSE77861 | UACA | 55075 | 236715_x_at | 0.3469 | 0.1389 | |
| SRP007169 | UACA | 55075 | RNAseq | -1.1155 | 0.0090 | |
| SRP008496 | UACA | 55075 | RNAseq | -0.8109 | 0.0105 | |
| SRP064894 | UACA | 55075 | RNAseq | -1.1973 | 0.0000 | |
| SRP133303 | UACA | 55075 | RNAseq | -0.7802 | 0.0000 | |
| SRP159526 | UACA | 55075 | RNAseq | -1.4496 | 0.0000 | |
| SRP193095 | UACA | 55075 | RNAseq | -1.3561 | 0.0000 | |
| SRP219564 | UACA | 55075 | RNAseq | -1.3196 | 0.0005 | |
| TCGA | UACA | 55075 | RNAseq | -0.2744 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by UACA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UACA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UACA | 55075 | 7 | 1 | 22 | |
| GSE20123 | UACA | 55075 | 7 | 1 | 22 | |
| GSE43470 | UACA | 55075 | 4 | 6 | 33 | |
| GSE46452 | UACA | 55075 | 3 | 7 | 49 | |
| GSE47630 | UACA | 55075 | 8 | 10 | 22 | |
| GSE54993 | UACA | 55075 | 5 | 6 | 59 | |
| GSE54994 | UACA | 55075 | 5 | 8 | 40 | |
| GSE60625 | UACA | 55075 | 4 | 4 | 3 | |
| GSE74703 | UACA | 55075 | 4 | 3 | 29 | |
| GSE74704 | UACA | 55075 | 3 | 1 | 16 | |
| TCGA | UACA | 55075 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 62; Total Number of normals: 366.
Somatic mutations of UACA:
Generating mutation plots.
Highly correlated genes for UACA:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UACA | HAUS2 | 0.917662 | 3 | 0 | 3 |
| UACA | ZNF160 | 0.848299 | 4 | 0 | 4 |
| UACA | C9orf64 | 0.847506 | 4 | 0 | 4 |
| UACA | FUT8-AS1 | 0.828751 | 3 | 0 | 3 |
| UACA | DIP2A | 0.827254 | 4 | 0 | 4 |
| UACA | CCDC152 | 0.823141 | 4 | 0 | 4 |
| UACA | CDK13 | 0.819754 | 4 | 0 | 4 |
| UACA | FBXW12 | 0.813075 | 4 | 0 | 4 |
| UACA | PGF | 0.80505 | 4 | 0 | 4 |
| UACA | MZT2B | 0.800823 | 4 | 0 | 4 |
| UACA | SLC22A3 | 0.800187 | 4 | 0 | 4 |
| UACA | DBT | 0.796306 | 4 | 0 | 4 |
| UACA | DLGAP4 | 0.79158 | 4 | 0 | 4 |
| UACA | NLN | 0.7888 | 4 | 0 | 3 |
| UACA | PECR | 0.78383 | 3 | 0 | 3 |
| UACA | SSBP3-AS1 | 0.768007 | 4 | 0 | 4 |
| UACA | UBXN2A | 0.756789 | 3 | 0 | 3 |
| UACA | SLC35E1 | 0.75473 | 4 | 0 | 3 |
| UACA | MAGI1 | 0.741613 | 3 | 0 | 3 |
| UACA | TRMT10B | 0.729067 | 3 | 0 | 3 |
For details and further investigation, click here
