| Full name: cell adhesion associated, oncogene regulated | Alias Symbol: ORCAM|CDO|CDON1 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 50937 | HGNC ID: HGNC:17104 | Ensembl Gene: ENSG00000064309 | OMIM ID: 608707 |
| Drug and gene relationship at DGIdb | |||
CDON involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04340 | Hedgehog signaling pathway |
Expression of CDON:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDON | 50937 | 227526_at | -0.2426 | 0.7045 | |
| GSE20347 | CDON | 50937 | 207230_at | 0.0684 | 0.5026 | |
| GSE23400 | CDON | 50937 | 207230_at | -0.0737 | 0.0404 | |
| GSE26886 | CDON | 50937 | 207230_at | 0.2731 | 0.0051 | |
| GSE29001 | CDON | 50937 | 207230_at | 0.1123 | 0.4857 | |
| GSE38129 | CDON | 50937 | 207230_at | -0.0534 | 0.5538 | |
| GSE45670 | CDON | 50937 | 207230_at | 0.1148 | 0.1550 | |
| GSE53622 | CDON | 50937 | 59069 | -1.2930 | 0.0000 | |
| GSE53624 | CDON | 50937 | 59069 | -0.6953 | 0.0000 | |
| GSE63941 | CDON | 50937 | 227526_at | -1.5105 | 0.0086 | |
| GSE77861 | CDON | 50937 | 207230_at | 0.0469 | 0.7482 | |
| GSE97050 | CDON | 50937 | A_32_P172141 | -0.6327 | 0.2665 | |
| SRP007169 | CDON | 50937 | RNAseq | 0.3095 | 0.6948 | |
| SRP064894 | CDON | 50937 | RNAseq | 0.2884 | 0.3755 | |
| SRP133303 | CDON | 50937 | RNAseq | -0.7661 | 0.0293 | |
| SRP159526 | CDON | 50937 | RNAseq | -0.0072 | 0.9885 | |
| SRP193095 | CDON | 50937 | RNAseq | -0.3567 | 0.1004 | |
| SRP219564 | CDON | 50937 | RNAseq | 0.1024 | 0.9058 | |
| TCGA | CDON | 50937 | RNAseq | -0.5561 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CDON expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDON:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDON | 50937 | 0 | 13 | 17 | |
| GSE20123 | CDON | 50937 | 0 | 13 | 17 | |
| GSE43470 | CDON | 50937 | 2 | 7 | 34 | |
| GSE46452 | CDON | 50937 | 3 | 26 | 30 | |
| GSE47630 | CDON | 50937 | 2 | 19 | 19 | |
| GSE54993 | CDON | 50937 | 10 | 0 | 60 | |
| GSE54994 | CDON | 50937 | 5 | 19 | 29 | |
| GSE60625 | CDON | 50937 | 0 | 3 | 8 | |
| GSE74703 | CDON | 50937 | 1 | 5 | 30 | |
| GSE74704 | CDON | 50937 | 0 | 9 | 11 | |
| TCGA | CDON | 50937 | 7 | 50 | 39 |
Total number of gains: 30; Total number of losses: 164; Total Number of normals: 294.
Somatic mutations of CDON:
Generating mutation plots.
Highly correlated genes for CDON:
Showing top 20/707 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDON | EMD | 0.790829 | 3 | 0 | 3 |
| CDON | MRPL33 | 0.774257 | 3 | 0 | 3 |
| CDON | TRIM47 | 0.767303 | 3 | 0 | 3 |
| CDON | SAG | 0.763653 | 5 | 0 | 5 |
| CDON | ANAPC16 | 0.761154 | 3 | 0 | 3 |
| CDON | BRI3 | 0.755054 | 3 | 0 | 3 |
| CDON | RNASEH2C | 0.743032 | 3 | 0 | 3 |
| CDON | NENF | 0.728227 | 3 | 0 | 3 |
| CDON | SLC25A23 | 0.728089 | 3 | 0 | 3 |
| CDON | CD151 | 0.721677 | 4 | 0 | 4 |
| CDON | NINJ1 | 0.720551 | 3 | 0 | 3 |
| CDON | FHOD3 | 0.718367 | 3 | 0 | 3 |
| CDON | ZNF358 | 0.716228 | 4 | 0 | 3 |
| CDON | CLIP2 | 0.71377 | 3 | 0 | 3 |
| CDON | PAQR3 | 0.709862 | 3 | 0 | 3 |
| CDON | SLC38A10 | 0.703573 | 3 | 0 | 3 |
| CDON | CHAT | 0.702424 | 4 | 0 | 4 |
| CDON | RGMB | 0.699503 | 4 | 0 | 3 |
| CDON | KRTCAP2 | 0.696412 | 3 | 0 | 3 |
| CDON | CKMT2 | 0.696269 | 4 | 0 | 3 |
For details and further investigation, click here
