| Full name: formin homology 2 domain containing 3 | Alias Symbol: FHOS2|KIAA1695|FLJ22297|FLJ22717 | ||
| Type: protein-coding gene | Cytoband: 18q12.2 | ||
| Entrez ID: 80206 | HGNC ID: HGNC:26178 | Ensembl Gene: ENSG00000134775 | OMIM ID: 609691 |
| Drug and gene relationship at DGIdb | |||
Expression of FHOD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FHOD3 | 80206 | 218980_at | -0.7325 | 0.3862 | |
| GSE20347 | FHOD3 | 80206 | 218980_at | 0.5276 | 0.0791 | |
| GSE23400 | FHOD3 | 80206 | 218980_at | 0.1014 | 0.3993 | |
| GSE26886 | FHOD3 | 80206 | 218980_at | 2.0684 | 0.0000 | |
| GSE29001 | FHOD3 | 80206 | 218980_at | 0.3413 | 0.3333 | |
| GSE38129 | FHOD3 | 80206 | 218980_at | 0.0799 | 0.8176 | |
| GSE45670 | FHOD3 | 80206 | 218980_at | -1.3601 | 0.0022 | |
| GSE63941 | FHOD3 | 80206 | 218980_at | -2.5687 | 0.0209 | |
| GSE77861 | FHOD3 | 80206 | 218980_at | 0.0235 | 0.9243 | |
| GSE97050 | FHOD3 | 80206 | A_32_P34444 | -0.2115 | 0.4985 | |
| SRP007169 | FHOD3 | 80206 | RNAseq | 1.4866 | 0.0563 | |
| SRP008496 | FHOD3 | 80206 | RNAseq | 2.8578 | 0.0000 | |
| SRP064894 | FHOD3 | 80206 | RNAseq | -0.2461 | 0.3635 | |
| SRP133303 | FHOD3 | 80206 | RNAseq | -0.0498 | 0.8808 | |
| SRP159526 | FHOD3 | 80206 | RNAseq | -0.1902 | 0.6436 | |
| SRP193095 | FHOD3 | 80206 | RNAseq | 0.6082 | 0.0373 | |
| SRP219564 | FHOD3 | 80206 | RNAseq | -0.5805 | 0.3476 | |
| TCGA | FHOD3 | 80206 | RNAseq | 0.1377 | 0.4480 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by FHOD3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FHOD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FHOD3 | 80206 | 2 | 5 | 23 | |
| GSE20123 | FHOD3 | 80206 | 2 | 5 | 23 | |
| GSE43470 | FHOD3 | 80206 | 0 | 3 | 40 | |
| GSE46452 | FHOD3 | 80206 | 1 | 25 | 33 | |
| GSE47630 | FHOD3 | 80206 | 5 | 20 | 15 | |
| GSE54993 | FHOD3 | 80206 | 8 | 1 | 61 | |
| GSE54994 | FHOD3 | 80206 | 1 | 16 | 36 | |
| GSE60625 | FHOD3 | 80206 | 0 | 4 | 7 | |
| GSE74703 | FHOD3 | 80206 | 0 | 3 | 33 | |
| GSE74704 | FHOD3 | 80206 | 1 | 4 | 15 | |
| TCGA | FHOD3 | 80206 | 15 | 43 | 38 |
Total number of gains: 35; Total number of losses: 129; Total Number of normals: 324.
Somatic mutations of FHOD3:
Generating mutation plots.
Highly correlated genes for FHOD3:
Showing top 20/647 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FHOD3 | POLR2G | 0.769457 | 3 | 0 | 3 |
| FHOD3 | C12orf57 | 0.76703 | 3 | 0 | 3 |
| FHOD3 | CLMP | 0.757044 | 3 | 0 | 3 |
| FHOD3 | SNX18 | 0.748574 | 3 | 0 | 3 |
| FHOD3 | SWAP70 | 0.740783 | 3 | 0 | 3 |
| FHOD3 | LRRC23 | 0.737258 | 3 | 0 | 3 |
| FHOD3 | KLHL13 | 0.733289 | 3 | 0 | 3 |
| FHOD3 | TCP11L1 | 0.729643 | 3 | 0 | 3 |
| FHOD3 | ZNF358 | 0.7286 | 3 | 0 | 3 |
| FHOD3 | SLC25A30 | 0.726843 | 3 | 0 | 3 |
| FHOD3 | FXN | 0.72268 | 3 | 0 | 3 |
| FHOD3 | MAP2K5 | 0.720673 | 3 | 0 | 3 |
| FHOD3 | CDON | 0.718367 | 3 | 0 | 3 |
| FHOD3 | C12orf65 | 0.707794 | 3 | 0 | 3 |
| FHOD3 | STAG2 | 0.704523 | 3 | 0 | 3 |
| FHOD3 | RNASEH2C | 0.702718 | 3 | 0 | 3 |
| FHOD3 | POLR3GL | 0.701998 | 3 | 0 | 3 |
| FHOD3 | G6PC3 | 0.699186 | 3 | 0 | 3 |
| FHOD3 | NFU1 | 0.698694 | 4 | 0 | 4 |
| FHOD3 | RNF214 | 0.698511 | 3 | 0 | 3 |
For details and further investigation, click here
