| Full name: mitochondrial ribosomal protein L33 | Alias Symbol: RPL33L | ||
| Type: protein-coding gene | Cytoband: 2p23.2 | ||
| Entrez ID: 9553 | HGNC ID: HGNC:14487 | Ensembl Gene: ENSG00000243147 | OMIM ID: 610059 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPL33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL33 | 9553 | 203781_at | -0.2100 | 0.6325 | |
| GSE20347 | MRPL33 | 9553 | 203781_at | 0.2570 | 0.1108 | |
| GSE23400 | MRPL33 | 9553 | 203781_at | 0.1375 | 0.0135 | |
| GSE26886 | MRPL33 | 9553 | 203781_at | 0.7368 | 0.0001 | |
| GSE29001 | MRPL33 | 9553 | 203781_at | 0.2501 | 0.2953 | |
| GSE38129 | MRPL33 | 9553 | 203781_at | 0.1471 | 0.2718 | |
| GSE45670 | MRPL33 | 9553 | 203781_at | 0.0786 | 0.6458 | |
| GSE53622 | MRPL33 | 9553 | 26756 | 0.1175 | 0.1400 | |
| GSE53624 | MRPL33 | 9553 | 26756 | 0.2304 | 0.0007 | |
| GSE63941 | MRPL33 | 9553 | 203781_at | 0.1548 | 0.7023 | |
| GSE77861 | MRPL33 | 9553 | 203781_at | 0.2983 | 0.0708 | |
| GSE97050 | MRPL33 | 9553 | A_24_P285480 | -0.2191 | 0.6004 | |
| SRP007169 | MRPL33 | 9553 | RNAseq | -0.2648 | 0.4983 | |
| SRP008496 | MRPL33 | 9553 | RNAseq | -0.0659 | 0.7858 | |
| SRP064894 | MRPL33 | 9553 | RNAseq | 0.2811 | 0.3184 | |
| SRP133303 | MRPL33 | 9553 | RNAseq | 0.2340 | 0.1374 | |
| SRP159526 | MRPL33 | 9553 | RNAseq | 0.5875 | 0.0103 | |
| SRP193095 | MRPL33 | 9553 | RNAseq | 0.1157 | 0.3744 | |
| SRP219564 | MRPL33 | 9553 | RNAseq | -0.5356 | 0.3325 | |
| TCGA | MRPL33 | 9553 | RNAseq | -0.0859 | 0.1200 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL33 | 9553 | 11 | 2 | 17 | |
| GSE20123 | MRPL33 | 9553 | 11 | 2 | 17 | |
| GSE43470 | MRPL33 | 9553 | 3 | 1 | 39 | |
| GSE46452 | MRPL33 | 9553 | 2 | 4 | 53 | |
| GSE47630 | MRPL33 | 9553 | 8 | 0 | 32 | |
| GSE54993 | MRPL33 | 9553 | 0 | 6 | 64 | |
| GSE54994 | MRPL33 | 9553 | 10 | 0 | 43 | |
| GSE60625 | MRPL33 | 9553 | 0 | 3 | 8 | |
| GSE74703 | MRPL33 | 9553 | 3 | 0 | 33 | |
| GSE74704 | MRPL33 | 9553 | 9 | 1 | 10 | |
| TCGA | MRPL33 | 9553 | 36 | 2 | 58 |
Total number of gains: 93; Total number of losses: 21; Total Number of normals: 374.
Somatic mutations of MRPL33:
Generating mutation plots.
Highly correlated genes for MRPL33:
Showing top 20/729 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL33 | GPR3 | 0.798444 | 3 | 0 | 3 |
| MRPL33 | MRGPRF | 0.789385 | 3 | 0 | 3 |
| MRPL33 | RDH14 | 0.787983 | 3 | 0 | 3 |
| MRPL33 | PRKG2 | 0.778866 | 3 | 0 | 3 |
| MRPL33 | CDON | 0.774257 | 3 | 0 | 3 |
| MRPL33 | KLHL31 | 0.771251 | 3 | 0 | 3 |
| MRPL33 | PET117 | 0.766475 | 3 | 0 | 3 |
| MRPL33 | ARHGEF33 | 0.752934 | 3 | 0 | 3 |
| MRPL33 | CDKN1C | 0.746516 | 3 | 0 | 3 |
| MRPL33 | MYADM | 0.732498 | 3 | 0 | 3 |
| MRPL33 | PSMG3 | 0.729716 | 3 | 0 | 3 |
| MRPL33 | ZBTB26 | 0.728114 | 3 | 0 | 3 |
| MRPL33 | MAK16 | 0.728069 | 5 | 0 | 5 |
| MRPL33 | TMEM184B | 0.727784 | 3 | 0 | 3 |
| MRPL33 | C19orf54 | 0.726582 | 3 | 0 | 3 |
| MRPL33 | FARS2 | 0.724756 | 3 | 0 | 3 |
| MRPL33 | DEGS1 | 0.724742 | 3 | 0 | 3 |
| MRPL33 | RASSF3 | 0.717832 | 3 | 0 | 3 |
| MRPL33 | MYCT1 | 0.712691 | 3 | 0 | 3 |
| MRPL33 | ANO6 | 0.710245 | 5 | 0 | 5 |
For details and further investigation, click here
