| Full name: ribonuclease H2 subunit C | Alias Symbol: AYP1|AGS3 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 84153 | HGNC ID: HGNC:24116 | Ensembl Gene: ENSG00000172922 | OMIM ID: 610330 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RNASEH2C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNASEH2C | 84153 | 226453_at | -0.1871 | 0.6528 | |
| GSE26886 | RNASEH2C | 84153 | 226453_at | 1.3677 | 0.0000 | |
| GSE45670 | RNASEH2C | 84153 | 226453_at | 0.1154 | 0.5089 | |
| GSE53622 | RNASEH2C | 84153 | 7154 | 0.1468 | 0.1904 | |
| GSE53624 | RNASEH2C | 84153 | 7154 | 0.6517 | 0.0000 | |
| GSE63941 | RNASEH2C | 84153 | 226453_at | -0.0185 | 0.9806 | |
| GSE77861 | RNASEH2C | 84153 | 226453_at | 0.1313 | 0.5519 | |
| GSE97050 | RNASEH2C | 84153 | A_33_P3358977 | -0.1666 | 0.4039 | |
| SRP007169 | RNASEH2C | 84153 | RNAseq | 0.0358 | 0.9359 | |
| SRP008496 | RNASEH2C | 84153 | RNAseq | -0.1421 | 0.6161 | |
| SRP064894 | RNASEH2C | 84153 | RNAseq | -0.1187 | 0.6483 | |
| SRP133303 | RNASEH2C | 84153 | RNAseq | 0.0584 | 0.7839 | |
| SRP159526 | RNASEH2C | 84153 | RNAseq | 0.3339 | 0.1985 | |
| SRP193095 | RNASEH2C | 84153 | RNAseq | 0.0062 | 0.9529 | |
| SRP219564 | RNASEH2C | 84153 | RNAseq | -0.0899 | 0.8212 | |
| TCGA | RNASEH2C | 84153 | RNAseq | -0.0397 | 0.5253 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RNASEH2C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNASEH2C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNASEH2C | 84153 | 8 | 5 | 17 | |
| GSE20123 | RNASEH2C | 84153 | 8 | 5 | 17 | |
| GSE43470 | RNASEH2C | 84153 | 6 | 1 | 36 | |
| GSE46452 | RNASEH2C | 84153 | 11 | 3 | 45 | |
| GSE47630 | RNASEH2C | 84153 | 7 | 5 | 28 | |
| GSE54993 | RNASEH2C | 84153 | 3 | 0 | 67 | |
| GSE54994 | RNASEH2C | 84153 | 7 | 5 | 41 | |
| GSE60625 | RNASEH2C | 84153 | 0 | 3 | 8 | |
| GSE74703 | RNASEH2C | 84153 | 4 | 0 | 32 | |
| GSE74704 | RNASEH2C | 84153 | 6 | 3 | 11 | |
| TCGA | RNASEH2C | 84153 | 23 | 7 | 66 |
Total number of gains: 83; Total number of losses: 37; Total Number of normals: 368.
Somatic mutations of RNASEH2C:
Generating mutation plots.
Highly correlated genes for RNASEH2C:
Showing top 20/353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNASEH2C | ZNF579 | 0.832371 | 3 | 0 | 3 |
| RNASEH2C | SF3A2 | 0.824729 | 3 | 0 | 3 |
| RNASEH2C | CREB5 | 0.82229 | 3 | 0 | 3 |
| RNASEH2C | CDKN1C | 0.801953 | 3 | 0 | 3 |
| RNASEH2C | CTBP2 | 0.801655 | 3 | 0 | 3 |
| RNASEH2C | EIF3G | 0.796966 | 3 | 0 | 3 |
| RNASEH2C | EFEMP2 | 0.781102 | 3 | 0 | 3 |
| RNASEH2C | XYLT2 | 0.770314 | 3 | 0 | 3 |
| RNASEH2C | C19orf54 | 0.77031 | 3 | 0 | 3 |
| RNASEH2C | RRAS2 | 0.768725 | 3 | 0 | 3 |
| RNASEH2C | TMTC1 | 0.766621 | 3 | 0 | 3 |
| RNASEH2C | ACY1 | 0.763601 | 3 | 0 | 3 |
| RNASEH2C | MRPL47 | 0.762914 | 3 | 0 | 3 |
| RNASEH2C | MCAM | 0.755508 | 3 | 0 | 3 |
| RNASEH2C | TMEM184B | 0.753622 | 3 | 0 | 3 |
| RNASEH2C | DMXL2 | 0.751991 | 3 | 0 | 3 |
| RNASEH2C | PCGF2 | 0.751436 | 3 | 0 | 3 |
| RNASEH2C | JDP2 | 0.751263 | 3 | 0 | 3 |
| RNASEH2C | PLXNA1 | 0.750786 | 3 | 0 | 3 |
| RNASEH2C | RAB30 | 0.745349 | 3 | 0 | 3 |
For details and further investigation, click here
