| Full name: anaphase promoting complex subunit 16 | Alias Symbol: bA570G20.3|FLJ33728|APC16|CENP-27 | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 119504 | HGNC ID: HGNC:26976 | Ensembl Gene: ENSG00000166295 | OMIM ID: 613427 |
| Drug and gene relationship at DGIdb | |||
Expression of ANAPC16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANAPC16 | 119504 | 224664_at | -0.4118 | 0.2928 | |
| GSE26886 | ANAPC16 | 119504 | 224664_at | -0.0171 | 0.9456 | |
| GSE45670 | ANAPC16 | 119504 | 224667_x_at | 0.1789 | 0.0853 | |
| GSE53622 | ANAPC16 | 119504 | 116112 | -0.8031 | 0.0000 | |
| GSE53624 | ANAPC16 | 119504 | 116112 | -0.4455 | 0.0000 | |
| GSE63941 | ANAPC16 | 119504 | 224664_at | 0.6802 | 0.0961 | |
| GSE77861 | ANAPC16 | 119504 | 224664_at | -0.3216 | 0.2854 | |
| GSE97050 | ANAPC16 | 119504 | A_33_P3216955 | -0.8856 | 0.0631 | |
| SRP007169 | ANAPC16 | 119504 | RNAseq | -0.6456 | 0.1035 | |
| SRP008496 | ANAPC16 | 119504 | RNAseq | -0.2566 | 0.2333 | |
| SRP064894 | ANAPC16 | 119504 | RNAseq | -0.5482 | 0.0036 | |
| SRP133303 | ANAPC16 | 119504 | RNAseq | -0.1863 | 0.0307 | |
| SRP159526 | ANAPC16 | 119504 | RNAseq | -0.4023 | 0.1190 | |
| SRP193095 | ANAPC16 | 119504 | RNAseq | -0.4430 | 0.0000 | |
| SRP219564 | ANAPC16 | 119504 | RNAseq | -0.5796 | 0.1406 | |
| TCGA | ANAPC16 | 119504 | RNAseq | -0.2002 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANAPC16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANAPC16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANAPC16 | 119504 | 3 | 4 | 23 | |
| GSE20123 | ANAPC16 | 119504 | 3 | 3 | 24 | |
| GSE43470 | ANAPC16 | 119504 | 1 | 8 | 34 | |
| GSE46452 | ANAPC16 | 119504 | 0 | 11 | 48 | |
| GSE47630 | ANAPC16 | 119504 | 2 | 14 | 24 | |
| GSE54993 | ANAPC16 | 119504 | 7 | 0 | 63 | |
| GSE54994 | ANAPC16 | 119504 | 2 | 11 | 40 | |
| GSE60625 | ANAPC16 | 119504 | 0 | 0 | 11 | |
| GSE74703 | ANAPC16 | 119504 | 1 | 5 | 30 | |
| GSE74704 | ANAPC16 | 119504 | 2 | 1 | 17 | |
| TCGA | ANAPC16 | 119504 | 11 | 23 | 62 |
Total number of gains: 32; Total number of losses: 80; Total Number of normals: 376.
Somatic mutations of ANAPC16:
Generating mutation plots.
Highly correlated genes for ANAPC16:
Showing top 20/468 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANAPC16 | ZBTB16 | 0.827933 | 3 | 0 | 3 |
| ANAPC16 | ZNF510 | 0.790644 | 3 | 0 | 3 |
| ANAPC16 | CHRDL1 | 0.790283 | 3 | 0 | 3 |
| ANAPC16 | PIK3C2A | 0.784696 | 4 | 0 | 4 |
| ANAPC16 | MAOB | 0.777173 | 4 | 0 | 4 |
| ANAPC16 | MEF2D | 0.77514 | 3 | 0 | 3 |
| ANAPC16 | ANKRA2 | 0.773846 | 3 | 0 | 3 |
| ANAPC16 | KAT6B | 0.773025 | 4 | 0 | 4 |
| ANAPC16 | SOBP | 0.770354 | 3 | 0 | 3 |
| ANAPC16 | BCAS2 | 0.768631 | 3 | 0 | 3 |
| ANAPC16 | EZH1 | 0.767664 | 4 | 0 | 4 |
| ANAPC16 | DET1 | 0.764874 | 3 | 0 | 3 |
| ANAPC16 | CDON | 0.761154 | 3 | 0 | 3 |
| ANAPC16 | LYRM1 | 0.756416 | 3 | 0 | 3 |
| ANAPC16 | SEC31B | 0.75596 | 3 | 0 | 3 |
| ANAPC16 | TGFBR3 | 0.751508 | 4 | 0 | 3 |
| ANAPC16 | LIMCH1 | 0.749305 | 3 | 0 | 3 |
| ANAPC16 | CSDE1 | 0.747319 | 5 | 0 | 4 |
| ANAPC16 | TSPYL2 | 0.746105 | 3 | 0 | 3 |
| ANAPC16 | PDS5B | 0.744231 | 3 | 0 | 3 |
For details and further investigation, click here
