| Full name: progestin and adipoQ receptor family member 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.21 | ||
| Entrez ID: 152559 | HGNC ID: HGNC:30130 | Ensembl Gene: ENSG00000163291 | OMIM ID: 614577 |
| Drug and gene relationship at DGIdb | |||
Expression of PAQR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAQR3 | 152559 | 213372_at | 0.3583 | 0.7000 | |
| GSE20347 | PAQR3 | 152559 | 213372_at | 0.1444 | 0.5733 | |
| GSE23400 | PAQR3 | 152559 | 213372_at | 0.2321 | 0.0685 | |
| GSE26886 | PAQR3 | 152559 | 213372_at | 0.8396 | 0.0053 | |
| GSE29001 | PAQR3 | 152559 | 213372_at | 0.5277 | 0.1815 | |
| GSE38129 | PAQR3 | 152559 | 213372_at | 0.1909 | 0.3758 | |
| GSE45670 | PAQR3 | 152559 | 213372_at | 0.2330 | 0.4269 | |
| GSE53622 | PAQR3 | 152559 | 112583 | 0.2238 | 0.0361 | |
| GSE53624 | PAQR3 | 152559 | 112583 | 0.4069 | 0.0000 | |
| GSE63941 | PAQR3 | 152559 | 213372_at | -0.4029 | 0.4823 | |
| GSE77861 | PAQR3 | 152559 | 213372_at | 1.0570 | 0.0441 | |
| GSE97050 | PAQR3 | 152559 | A_23_P337875 | -0.0908 | 0.8519 | |
| SRP007169 | PAQR3 | 152559 | RNAseq | 0.3992 | 0.2486 | |
| SRP008496 | PAQR3 | 152559 | RNAseq | 0.5530 | 0.0016 | |
| SRP064894 | PAQR3 | 152559 | RNAseq | -0.2026 | 0.4437 | |
| SRP133303 | PAQR3 | 152559 | RNAseq | 0.2002 | 0.3271 | |
| SRP159526 | PAQR3 | 152559 | RNAseq | -0.3897 | 0.0420 | |
| SRP193095 | PAQR3 | 152559 | RNAseq | -0.2368 | 0.0557 | |
| SRP219564 | PAQR3 | 152559 | RNAseq | -0.3001 | 0.3551 | |
| TCGA | PAQR3 | 152559 | RNAseq | 0.1015 | 0.1788 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PAQR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAQR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAQR3 | 152559 | 1 | 10 | 19 | |
| GSE20123 | PAQR3 | 152559 | 1 | 10 | 19 | |
| GSE43470 | PAQR3 | 152559 | 0 | 13 | 30 | |
| GSE46452 | PAQR3 | 152559 | 1 | 36 | 22 | |
| GSE47630 | PAQR3 | 152559 | 1 | 19 | 20 | |
| GSE54993 | PAQR3 | 152559 | 8 | 0 | 62 | |
| GSE54994 | PAQR3 | 152559 | 0 | 9 | 44 | |
| GSE60625 | PAQR3 | 152559 | 0 | 0 | 11 | |
| GSE74703 | PAQR3 | 152559 | 0 | 11 | 25 | |
| GSE74704 | PAQR3 | 152559 | 1 | 6 | 13 | |
| TCGA | PAQR3 | 152559 | 12 | 33 | 51 |
Total number of gains: 25; Total number of losses: 147; Total Number of normals: 316.
Somatic mutations of PAQR3:
Generating mutation plots.
Highly correlated genes for PAQR3:
Showing top 20/671 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAQR3 | IGSF11 | 0.830819 | 3 | 0 | 3 |
| PAQR3 | DZIP3 | 0.774315 | 3 | 0 | 3 |
| PAQR3 | TBC1D19 | 0.744579 | 3 | 0 | 3 |
| PAQR3 | MTRR | 0.735672 | 3 | 0 | 3 |
| PAQR3 | PHIP | 0.735117 | 5 | 0 | 4 |
| PAQR3 | FAM13B | 0.729109 | 3 | 0 | 3 |
| PAQR3 | CDON | 0.709862 | 3 | 0 | 3 |
| PAQR3 | POLR1B | 0.703353 | 3 | 0 | 3 |
| PAQR3 | TGOLN2 | 0.701979 | 3 | 0 | 3 |
| PAQR3 | POLA1 | 0.701181 | 3 | 0 | 3 |
| PAQR3 | NPTN | 0.689933 | 4 | 0 | 4 |
| PAQR3 | NAP1L5 | 0.689793 | 3 | 0 | 3 |
| PAQR3 | KLHL24 | 0.688245 | 3 | 0 | 3 |
| PAQR3 | ZDHHC4 | 0.683788 | 4 | 0 | 3 |
| PAQR3 | DHRSX | 0.682108 | 3 | 0 | 3 |
| PAQR3 | ZDHHC7 | 0.678767 | 3 | 0 | 3 |
| PAQR3 | TNFRSF10B | 0.678536 | 3 | 0 | 3 |
| PAQR3 | ZBTB26 | 0.674489 | 3 | 0 | 3 |
| PAQR3 | WDR81 | 0.673415 | 3 | 0 | 3 |
| PAQR3 | CTDSPL2 | 0.670232 | 4 | 0 | 4 |
For details and further investigation, click here
