| Full name: repulsive guidance molecule BMP co-receptor b | Alias Symbol: FLJ90406|DRAGON | ||
| Type: protein-coding gene | Cytoband: 5q15 | ||
| Entrez ID: 285704 | HGNC ID: HGNC:26896 | Ensembl Gene: ENSG00000174136 | OMIM ID: 612687 |
| Drug and gene relationship at DGIdb | |||
Expression of RGMB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGMB | 285704 | 226989_at | -0.4732 | 0.6371 | |
| GSE26886 | RGMB | 285704 | 226989_at | 1.1547 | 0.0145 | |
| GSE45670 | RGMB | 285704 | 226989_at | -0.4532 | 0.2042 | |
| GSE53622 | RGMB | 285704 | 147057 | -0.7143 | 0.0000 | |
| GSE53624 | RGMB | 285704 | 147057 | -0.2511 | 0.0169 | |
| GSE63941 | RGMB | 285704 | 226989_at | -2.4248 | 0.0050 | |
| GSE77861 | RGMB | 285704 | 226989_at | -0.1689 | 0.3105 | |
| GSE97050 | RGMB | 285704 | A_24_P363100 | -1.0859 | 0.1140 | |
| SRP007169 | RGMB | 285704 | RNAseq | 1.0227 | 0.0943 | |
| SRP008496 | RGMB | 285704 | RNAseq | 1.1956 | 0.0022 | |
| SRP064894 | RGMB | 285704 | RNAseq | 0.4177 | 0.1150 | |
| SRP133303 | RGMB | 285704 | RNAseq | -0.5552 | 0.0008 | |
| SRP159526 | RGMB | 285704 | RNAseq | -0.1335 | 0.7729 | |
| SRP193095 | RGMB | 285704 | RNAseq | -0.5236 | 0.0028 | |
| SRP219564 | RGMB | 285704 | RNAseq | -0.0302 | 0.9755 | |
| TCGA | RGMB | 285704 | RNAseq | -0.6348 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by RGMB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGMB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGMB | 285704 | 1 | 13 | 16 | |
| GSE20123 | RGMB | 285704 | 1 | 13 | 16 | |
| GSE43470 | RGMB | 285704 | 3 | 9 | 31 | |
| GSE46452 | RGMB | 285704 | 0 | 28 | 31 | |
| GSE47630 | RGMB | 285704 | 0 | 20 | 20 | |
| GSE54993 | RGMB | 285704 | 8 | 1 | 61 | |
| GSE54994 | RGMB | 285704 | 1 | 18 | 34 | |
| GSE60625 | RGMB | 285704 | 0 | 0 | 11 | |
| GSE74703 | RGMB | 285704 | 2 | 7 | 27 | |
| GSE74704 | RGMB | 285704 | 1 | 7 | 12 | |
| TCGA | RGMB | 285704 | 3 | 43 | 50 |
Total number of gains: 20; Total number of losses: 159; Total Number of normals: 309.
Somatic mutations of RGMB:
Generating mutation plots.
Highly correlated genes for RGMB:
Showing top 20/827 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGMB | HABP4 | 0.874284 | 3 | 0 | 3 |
| RGMB | UBXN10 | 0.846901 | 3 | 0 | 3 |
| RGMB | TLN1 | 0.83129 | 3 | 0 | 3 |
| RGMB | AFF3 | 0.812019 | 3 | 0 | 3 |
| RGMB | MAP4 | 0.804246 | 3 | 0 | 3 |
| RGMB | ZBTB26 | 0.803419 | 3 | 0 | 3 |
| RGMB | ESRRG | 0.802901 | 3 | 0 | 3 |
| RGMB | ILK | 0.802109 | 4 | 0 | 4 |
| RGMB | ZFAND5 | 0.800384 | 3 | 0 | 3 |
| RGMB | FYCO1 | 0.780278 | 4 | 0 | 4 |
| RGMB | TIMP3 | 0.779105 | 3 | 0 | 3 |
| RGMB | CDS2 | 0.77902 | 3 | 0 | 3 |
| RGMB | MYEF2 | 0.774513 | 3 | 0 | 3 |
| RGMB | SYNC | 0.769816 | 4 | 0 | 3 |
| RGMB | TOR1AIP1 | 0.765724 | 4 | 0 | 4 |
| RGMB | FAM124A | 0.760026 | 4 | 0 | 4 |
| RGMB | PDHB | 0.754225 | 3 | 0 | 3 |
| RGMB | PLA2G5 | 0.753644 | 3 | 0 | 3 |
| RGMB | PGRMC1 | 0.7535 | 3 | 0 | 3 |
| RGMB | PTPN21 | 0.75323 | 3 | 0 | 3 |
For details and further investigation, click here
