| Full name: caudal type homeobox 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q12.2 | ||
| Entrez ID: 1045 | HGNC ID: HGNC:1806 | Ensembl Gene: ENSG00000165556 | OMIM ID: 600297 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CDX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDX2 | 1045 | 206387_at | 0.0789 | 0.8664 | |
| GSE20347 | CDX2 | 1045 | 206387_at | -0.0708 | 0.4357 | |
| GSE23400 | CDX2 | 1045 | 206387_at | -0.1691 | 0.0009 | |
| GSE26886 | CDX2 | 1045 | 206387_at | 0.2579 | 0.0077 | |
| GSE29001 | CDX2 | 1045 | 206387_at | -0.4776 | 0.0178 | |
| GSE38129 | CDX2 | 1045 | 206387_at | -0.1376 | 0.2417 | |
| GSE45670 | CDX2 | 1045 | 206387_at | -0.1524 | 0.2853 | |
| GSE53622 | CDX2 | 1045 | 21618 | 0.2307 | 0.0136 | |
| GSE53624 | CDX2 | 1045 | 21618 | 0.6130 | 0.0000 | |
| GSE63941 | CDX2 | 1045 | 206387_at | 0.7176 | 0.0423 | |
| GSE77861 | CDX2 | 1045 | 206387_at | -0.1752 | 0.2765 | |
| GSE97050 | CDX2 | 1045 | A_33_P3304501 | 0.1079 | 0.5869 | |
| TCGA | CDX2 | 1045 | RNAseq | 2.2619 | 0.0032 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CDX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDX2 | 1045 | 1 | 14 | 15 | |
| GSE20123 | CDX2 | 1045 | 1 | 12 | 17 | |
| GSE43470 | CDX2 | 1045 | 2 | 12 | 29 | |
| GSE46452 | CDX2 | 1045 | 0 | 33 | 26 | |
| GSE47630 | CDX2 | 1045 | 3 | 26 | 11 | |
| GSE54993 | CDX2 | 1045 | 11 | 2 | 57 | |
| GSE54994 | CDX2 | 1045 | 1 | 13 | 39 | |
| GSE60625 | CDX2 | 1045 | 0 | 3 | 8 | |
| GSE74703 | CDX2 | 1045 | 2 | 9 | 25 | |
| GSE74704 | CDX2 | 1045 | 0 | 10 | 10 | |
| TCGA | CDX2 | 1045 | 7 | 39 | 50 |
Total number of gains: 28; Total number of losses: 173; Total Number of normals: 287.
Somatic mutations of CDX2:
Generating mutation plots.
Highly correlated genes for CDX2:
Showing top 20/684 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDX2 | PGC | 0.809062 | 3 | 0 | 3 |
| CDX2 | GPR182 | 0.800284 | 4 | 0 | 4 |
| CDX2 | MGAT5B | 0.784466 | 3 | 0 | 3 |
| CDX2 | APOM | 0.776398 | 4 | 0 | 4 |
| CDX2 | ST8SIA3 | 0.769109 | 3 | 0 | 3 |
| CDX2 | SNORA71A | 0.761838 | 3 | 0 | 3 |
| CDX2 | CUZD1 | 0.740223 | 3 | 0 | 3 |
| CDX2 | FERD3L | 0.739493 | 3 | 0 | 3 |
| CDX2 | EVX1 | 0.731341 | 5 | 0 | 5 |
| CDX2 | CLCN1 | 0.730112 | 5 | 0 | 5 |
| CDX2 | RNF215 | 0.726333 | 3 | 0 | 3 |
| CDX2 | ATG16L1 | 0.724486 | 3 | 0 | 3 |
| CDX2 | TBKBP1 | 0.723549 | 7 | 0 | 7 |
| CDX2 | AICDA | 0.722003 | 3 | 0 | 3 |
| CDX2 | MMP17 | 0.719505 | 4 | 0 | 3 |
| CDX2 | JSRP1 | 0.718088 | 4 | 0 | 4 |
| CDX2 | SBNO2 | 0.716642 | 4 | 0 | 3 |
| CDX2 | C10orf90 | 0.715246 | 3 | 0 | 3 |
| CDX2 | BTNL2 | 0.712966 | 6 | 0 | 6 |
| CDX2 | NPPA | 0.712847 | 6 | 0 | 5 |
For details and further investigation, click here
