| Full name: even-skipped homeobox 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p15.2 | ||
| Entrez ID: 2128 | HGNC ID: HGNC:3506 | Ensembl Gene: ENSG00000106038 | OMIM ID: 142996 |
| Drug and gene relationship at DGIdb | |||
Expression of EVX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EVX1 | 2128 | 207914_x_at | 0.0388 | 0.8589 | |
| GSE20347 | EVX1 | 2128 | 207914_x_at | 0.0305 | 0.8030 | |
| GSE23400 | EVX1 | 2128 | 207914_x_at | -0.1656 | 0.0000 | |
| GSE26886 | EVX1 | 2128 | 207914_x_at | 0.6487 | 0.0005 | |
| GSE29001 | EVX1 | 2128 | 207914_x_at | -0.0153 | 0.9434 | |
| GSE38129 | EVX1 | 2128 | 207914_x_at | -0.1029 | 0.4347 | |
| GSE45670 | EVX1 | 2128 | 207914_x_at | -0.0757 | 0.4686 | |
| GSE53622 | EVX1 | 2128 | 12433 | 0.1238 | 0.1063 | |
| GSE53624 | EVX1 | 2128 | 12433 | 0.0177 | 0.8561 | |
| GSE63941 | EVX1 | 2128 | 207914_x_at | -0.0837 | 0.6483 | |
| GSE77861 | EVX1 | 2128 | 207914_x_at | -0.0208 | 0.9128 | |
| GSE97050 | EVX1 | 2128 | A_24_P368943 | -0.1990 | 0.4336 | |
| TCGA | EVX1 | 2128 | RNAseq | 1.3857 | 0.4956 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EVX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EVX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EVX1 | 2128 | 16 | 1 | 13 | |
| GSE20123 | EVX1 | 2128 | 16 | 1 | 13 | |
| GSE43470 | EVX1 | 2128 | 4 | 0 | 39 | |
| GSE46452 | EVX1 | 2128 | 10 | 2 | 47 | |
| GSE47630 | EVX1 | 2128 | 8 | 1 | 31 | |
| GSE54993 | EVX1 | 2128 | 0 | 6 | 64 | |
| GSE54994 | EVX1 | 2128 | 20 | 2 | 31 | |
| GSE60625 | EVX1 | 2128 | 0 | 0 | 11 | |
| GSE74703 | EVX1 | 2128 | 4 | 0 | 32 | |
| GSE74704 | EVX1 | 2128 | 10 | 1 | 9 | |
| TCGA | EVX1 | 2128 | 55 | 6 | 35 |
Total number of gains: 143; Total number of losses: 20; Total Number of normals: 325.
Somatic mutations of EVX1:
Generating mutation plots.
Highly correlated genes for EVX1:
Showing top 20/1053 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EVX1 | TSPAN11 | 0.843712 | 3 | 0 | 3 |
| EVX1 | KLRG2 | 0.823678 | 3 | 0 | 3 |
| EVX1 | C1QL2 | 0.820538 | 3 | 0 | 3 |
| EVX1 | DCDC1 | 0.816555 | 3 | 0 | 3 |
| EVX1 | STRC | 0.811792 | 3 | 0 | 3 |
| EVX1 | C2CD4D | 0.810768 | 3 | 0 | 3 |
| EVX1 | WDR90 | 0.810616 | 3 | 0 | 3 |
| EVX1 | MRGPRG | 0.804349 | 3 | 0 | 3 |
| EVX1 | ARHGAP30 | 0.797675 | 4 | 0 | 4 |
| EVX1 | YY2 | 0.796921 | 3 | 0 | 3 |
| EVX1 | MEGF11 | 0.794091 | 3 | 0 | 3 |
| EVX1 | LBX2 | 0.787884 | 3 | 0 | 3 |
| EVX1 | C19orf81 | 0.783906 | 4 | 0 | 4 |
| EVX1 | CDC34 | 0.783267 | 3 | 0 | 3 |
| EVX1 | C9orf153 | 0.783019 | 3 | 0 | 3 |
| EVX1 | WNT9A | 0.779261 | 3 | 0 | 3 |
| EVX1 | BSX | 0.777748 | 3 | 0 | 3 |
| EVX1 | MGAT5B | 0.776433 | 4 | 0 | 4 |
| EVX1 | PABPN1L | 0.769587 | 3 | 0 | 3 |
| EVX1 | MRGPRE | 0.768957 | 3 | 0 | 3 |
For details and further investigation, click here
