| Full name: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B | Alias Symbol: GnT-IX|FLJ25132|GnT-VB | ||
| Type: protein-coding gene | Cytoband: 17q25.2 | ||
| Entrez ID: 146664 | HGNC ID: HGNC:24140 | Ensembl Gene: ENSG00000167889 | OMIM ID: 612441 |
| Drug and gene relationship at DGIdb | |||
Expression of MGAT5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MGAT5B | 146664 | 238445_x_at | -0.1093 | 0.6360 | |
| GSE26886 | MGAT5B | 146664 | 238445_x_at | 0.6560 | 0.0004 | |
| GSE45670 | MGAT5B | 146664 | 238445_x_at | 0.0008 | 0.9962 | |
| GSE53622 | MGAT5B | 146664 | 10226 | -0.0557 | 0.5278 | |
| GSE53624 | MGAT5B | 146664 | 10226 | -0.6958 | 0.0000 | |
| GSE63941 | MGAT5B | 146664 | 238445_x_at | 0.6046 | 0.1335 | |
| GSE77861 | MGAT5B | 146664 | 238445_x_at | -0.0879 | 0.7418 | |
| GSE97050 | MGAT5B | 146664 | A_24_P138784 | 0.0623 | 0.8183 | |
| SRP159526 | MGAT5B | 146664 | RNAseq | 2.8253 | 0.0000 | |
| SRP219564 | MGAT5B | 146664 | RNAseq | 3.8033 | 0.0000 | |
| TCGA | MGAT5B | 146664 | RNAseq | 0.3414 | 0.4051 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MGAT5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MGAT5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MGAT5B | 146664 | 7 | 2 | 21 | |
| GSE20123 | MGAT5B | 146664 | 7 | 2 | 21 | |
| GSE43470 | MGAT5B | 146664 | 4 | 3 | 36 | |
| GSE46452 | MGAT5B | 146664 | 33 | 1 | 25 | |
| GSE47630 | MGAT5B | 146664 | 8 | 1 | 31 | |
| GSE54993 | MGAT5B | 146664 | 2 | 5 | 63 | |
| GSE54994 | MGAT5B | 146664 | 10 | 4 | 39 | |
| GSE60625 | MGAT5B | 146664 | 6 | 0 | 5 | |
| GSE74703 | MGAT5B | 146664 | 4 | 1 | 31 | |
| GSE74704 | MGAT5B | 146664 | 5 | 1 | 14 | |
| TCGA | MGAT5B | 146664 | 31 | 9 | 56 |
Total number of gains: 117; Total number of losses: 29; Total Number of normals: 342.
Somatic mutations of MGAT5B:
Generating mutation plots.
Highly correlated genes for MGAT5B:
Showing top 20/335 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MGAT5B | MEX3D | 0.881685 | 3 | 0 | 3 |
| MGAT5B | HDAC10 | 0.831296 | 3 | 0 | 3 |
| MGAT5B | LIM2 | 0.829451 | 3 | 0 | 3 |
| MGAT5B | BARHL2 | 0.807099 | 3 | 0 | 3 |
| MGAT5B | RPP25 | 0.801911 | 3 | 0 | 3 |
| MGAT5B | CLEC18C | 0.799074 | 3 | 0 | 3 |
| MGAT5B | RASL10B | 0.79892 | 4 | 0 | 4 |
| MGAT5B | NOX1 | 0.798326 | 3 | 0 | 3 |
| MGAT5B | ARFIP2 | 0.795857 | 3 | 0 | 3 |
| MGAT5B | ZIC1 | 0.794631 | 3 | 0 | 3 |
| MGAT5B | ARHGAP30 | 0.792103 | 3 | 0 | 3 |
| MGAT5B | DOHH | 0.789074 | 3 | 0 | 3 |
| MGAT5B | GNL1 | 0.786773 | 3 | 0 | 3 |
| MGAT5B | CDX2 | 0.784466 | 3 | 0 | 3 |
| MGAT5B | LRFN3 | 0.784463 | 3 | 0 | 3 |
| MGAT5B | GRIN1 | 0.783773 | 3 | 0 | 3 |
| MGAT5B | GPHB5 | 0.778792 | 4 | 0 | 4 |
| MGAT5B | PROC | 0.776905 | 3 | 0 | 3 |
| MGAT5B | ADM2 | 0.776579 | 3 | 0 | 3 |
| MGAT5B | EVX1 | 0.776433 | 4 | 0 | 4 |
For details and further investigation, click here
