| Full name: carboxypeptidase Q | Alias Symbol: LDP|PGCP | ||
| Type: protein-coding gene | Cytoband: 8q22.1 | ||
| Entrez ID: 10404 | HGNC ID: HGNC:16910 | Ensembl Gene: ENSG00000104324 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CPQ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPQ | 10404 | 208454_s_at | -0.2930 | 0.7745 | |
| GSE20347 | CPQ | 10404 | 208454_s_at | -0.0133 | 0.9009 | |
| GSE23400 | CPQ | 10404 | 208454_s_at | -0.0572 | 0.4377 | |
| GSE26886 | CPQ | 10404 | 208454_s_at | 0.6616 | 0.0055 | |
| GSE29001 | CPQ | 10404 | 203501_at | -0.0733 | 0.7840 | |
| GSE38129 | CPQ | 10404 | 208454_s_at | -0.2995 | 0.1727 | |
| GSE45670 | CPQ | 10404 | 208454_s_at | -1.2408 | 0.0000 | |
| GSE53622 | CPQ | 10404 | 142836 | -0.0743 | 0.5944 | |
| GSE53624 | CPQ | 10404 | 142836 | -0.2293 | 0.1350 | |
| GSE63941 | CPQ | 10404 | 208454_s_at | -3.3313 | 0.0000 | |
| GSE77861 | CPQ | 10404 | 208454_s_at | -0.1250 | 0.2457 | |
| SRP007169 | CPQ | 10404 | RNAseq | 1.0111 | 0.0432 | |
| SRP008496 | CPQ | 10404 | RNAseq | 1.3271 | 0.0001 | |
| SRP064894 | CPQ | 10404 | RNAseq | -0.0450 | 0.8880 | |
| SRP133303 | CPQ | 10404 | RNAseq | -0.1613 | 0.5596 | |
| SRP159526 | CPQ | 10404 | RNAseq | 0.3198 | 0.2408 | |
| SRP193095 | CPQ | 10404 | RNAseq | 0.2015 | 0.5244 | |
| SRP219564 | CPQ | 10404 | RNAseq | -0.0684 | 0.9222 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by CPQ expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CPQ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPQ | 10404 | 16 | 0 | 14 | |
| GSE20123 | CPQ | 10404 | 17 | 0 | 13 | |
| GSE43470 | CPQ | 10404 | 21 | 1 | 21 | |
| GSE46452 | CPQ | 10404 | 23 | 0 | 36 | |
| GSE47630 | CPQ | 10404 | 24 | 0 | 16 | |
| GSE54993 | CPQ | 10404 | 0 | 20 | 50 | |
| GSE54994 | CPQ | 10404 | 35 | 1 | 17 | |
| GSE60625 | CPQ | 10404 | 0 | 4 | 7 | |
| GSE74703 | CPQ | 10404 | 18 | 1 | 17 | |
| GSE74704 | CPQ | 10404 | 12 | 0 | 8 | |
| TCGA | CPQ | 10404 | 56 | 3 | 37 |
Total number of gains: 222; Total number of losses: 30; Total Number of normals: 236.
Somatic mutations of CPQ:
Generating mutation plots.
Highly correlated genes for CPQ:
Showing top 20/665 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPQ | FIBIN | 0.830819 | 3 | 0 | 3 |
| CPQ | TIMP3 | 0.805346 | 5 | 0 | 5 |
| CPQ | MGARP | 0.779799 | 3 | 0 | 3 |
| CPQ | GNG2 | 0.759057 | 4 | 0 | 4 |
| CPQ | ZCCHC18 | 0.739232 | 4 | 0 | 4 |
| CPQ | GPC6 | 0.739135 | 5 | 0 | 5 |
| CPQ | ZFPM2 | 0.726785 | 8 | 0 | 8 |
| CPQ | DNM3OS | 0.724754 | 3 | 0 | 3 |
| CPQ | OLFML3 | 0.724397 | 7 | 0 | 7 |
| CPQ | LINC00968 | 0.715194 | 4 | 0 | 4 |
| CPQ | SYT11 | 0.706861 | 9 | 0 | 8 |
| CPQ | PCDH9 | 0.704494 | 6 | 0 | 5 |
| CPQ | SPATA9 | 0.702871 | 3 | 0 | 3 |
| CPQ | ZCCHC24 | 0.702311 | 8 | 0 | 8 |
| CPQ | STARD9 | 0.701914 | 4 | 0 | 4 |
| CPQ | TBX5 | 0.699656 | 5 | 0 | 5 |
| CPQ | MAGI2-AS3 | 0.699161 | 5 | 0 | 5 |
| CPQ | TMEM204 | 0.697649 | 5 | 0 | 5 |
| CPQ | ARMCX1 | 0.696977 | 8 | 0 | 8 |
| CPQ | BICC1 | 0.695251 | 7 | 0 | 6 |
For details and further investigation, click here
