| Full name: BicC family RNA binding protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q21.1 | ||
| Entrez ID: 80114 | HGNC ID: HGNC:19351 | Ensembl Gene: ENSG00000122870 | OMIM ID: 614295 |
| Drug and gene relationship at DGIdb | |||
Expression of BICC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BICC1 | 80114 | 213429_at | -0.2210 | 0.8683 | |
| GSE20347 | BICC1 | 80114 | 213429_at | 0.5262 | 0.0152 | |
| GSE23400 | BICC1 | 80114 | 213429_at | 0.0059 | 0.9585 | |
| GSE26886 | BICC1 | 80114 | 220580_at | -0.0017 | 0.9912 | |
| GSE29001 | BICC1 | 80114 | 213429_at | -0.0877 | 0.7380 | |
| GSE38129 | BICC1 | 80114 | 213429_at | 0.2539 | 0.5465 | |
| GSE45670 | BICC1 | 80114 | 213429_at | -1.6351 | 0.0018 | |
| GSE53622 | BICC1 | 80114 | 12733 | 0.6878 | 0.0001 | |
| GSE53624 | BICC1 | 80114 | 12733 | 0.9857 | 0.0000 | |
| GSE63941 | BICC1 | 80114 | 213429_at | -6.7757 | 0.0000 | |
| GSE77861 | BICC1 | 80114 | 220580_at | -0.0165 | 0.8818 | |
| GSE97050 | BICC1 | 80114 | A_33_P3293913 | -0.0190 | 0.9684 | |
| SRP007169 | BICC1 | 80114 | RNAseq | 2.4699 | 0.0007 | |
| SRP008496 | BICC1 | 80114 | RNAseq | 3.0130 | 0.0000 | |
| SRP064894 | BICC1 | 80114 | RNAseq | 1.1870 | 0.0007 | |
| SRP133303 | BICC1 | 80114 | RNAseq | 1.1484 | 0.0007 | |
| SRP159526 | BICC1 | 80114 | RNAseq | 0.6390 | 0.0193 | |
| SRP193095 | BICC1 | 80114 | RNAseq | 2.3041 | 0.0000 | |
| SRP219564 | BICC1 | 80114 | RNAseq | 1.0555 | 0.1993 | |
| TCGA | BICC1 | 80114 | RNAseq | -0.1401 | 0.6190 |
Upregulated datasets: 5; Downregulated datasets: 2.
Survival by BICC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BICC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BICC1 | 80114 | 2 | 6 | 22 | |
| GSE20123 | BICC1 | 80114 | 2 | 6 | 22 | |
| GSE43470 | BICC1 | 80114 | 2 | 5 | 36 | |
| GSE46452 | BICC1 | 80114 | 1 | 11 | 47 | |
| GSE47630 | BICC1 | 80114 | 4 | 12 | 24 | |
| GSE54993 | BICC1 | 80114 | 9 | 0 | 61 | |
| GSE54994 | BICC1 | 80114 | 3 | 10 | 40 | |
| GSE60625 | BICC1 | 80114 | 0 | 0 | 11 | |
| GSE74703 | BICC1 | 80114 | 2 | 3 | 31 | |
| GSE74704 | BICC1 | 80114 | 1 | 4 | 15 | |
| TCGA | BICC1 | 80114 | 10 | 23 | 63 |
Total number of gains: 36; Total number of losses: 80; Total Number of normals: 372.
Somatic mutations of BICC1:
Generating mutation plots.
Highly correlated genes for BICC1:
Showing top 20/1122 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BICC1 | DNM3OS | 0.850841 | 3 | 0 | 3 |
| BICC1 | DAB2 | 0.807367 | 9 | 0 | 9 |
| BICC1 | FBN1 | 0.801263 | 8 | 0 | 7 |
| BICC1 | ZEB2 | 0.798543 | 7 | 0 | 7 |
| BICC1 | SLC39A13 | 0.780441 | 4 | 0 | 4 |
| BICC1 | GPC6 | 0.779336 | 7 | 0 | 6 |
| BICC1 | IQGAP2 | 0.772141 | 5 | 0 | 5 |
| BICC1 | NAP1L3 | 0.769197 | 8 | 0 | 8 |
| BICC1 | ANXA6 | 0.767027 | 9 | 0 | 9 |
| BICC1 | FSTL1 | 0.763394 | 10 | 0 | 9 |
| BICC1 | C11orf96 | 0.754905 | 4 | 0 | 3 |
| BICC1 | PRKG1 | 0.747285 | 7 | 0 | 6 |
| BICC1 | MRVI1 | 0.746673 | 5 | 0 | 5 |
| BICC1 | COLEC12 | 0.746667 | 10 | 0 | 9 |
| BICC1 | GLT8D2 | 0.74438 | 10 | 0 | 9 |
| BICC1 | COL6A1 | 0.743772 | 10 | 0 | 9 |
| BICC1 | DPYSL2 | 0.743104 | 9 | 0 | 9 |
| BICC1 | AXL | 0.742087 | 9 | 0 | 8 |
| BICC1 | PMP22 | 0.741493 | 11 | 0 | 9 |
| BICC1 | LIX1L | 0.739227 | 6 | 0 | 6 |
For details and further investigation, click here
