| Full name: synaptotagmin 11 | Alias Symbol: KIAA0080|MGC10881|MGC17226|DKFZp781D015 | ||
| Type: protein-coding gene | Cytoband: 1q22 | ||
| Entrez ID: 23208 | HGNC ID: HGNC:19239 | Ensembl Gene: ENSG00000132718 | OMIM ID: 608741 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT11 | 23208 | 209197_at | -0.4022 | 0.6916 | |
| GSE20347 | SYT11 | 23208 | 209197_at | 0.1982 | 0.0705 | |
| GSE23400 | SYT11 | 23208 | 209197_at | -0.1451 | 0.0160 | |
| GSE26886 | SYT11 | 23208 | 232677_at | 0.2001 | 0.0696 | |
| GSE29001 | SYT11 | 23208 | 209197_at | 0.0967 | 0.6998 | |
| GSE38129 | SYT11 | 23208 | 209197_at | -0.2807 | 0.3041 | |
| GSE45670 | SYT11 | 23208 | 209197_at | -0.7946 | 0.0073 | |
| GSE53622 | SYT11 | 23208 | 30618 | -0.0040 | 0.9796 | |
| GSE53624 | SYT11 | 23208 | 30618 | 0.0533 | 0.7486 | |
| GSE63941 | SYT11 | 23208 | 209197_at | -4.3234 | 0.0000 | |
| GSE77861 | SYT11 | 23208 | 209197_at | 0.0380 | 0.7661 | |
| GSE97050 | SYT11 | 23208 | A_24_P248240 | 0.2069 | 0.5360 | |
| SRP007169 | SYT11 | 23208 | RNAseq | 2.8130 | 0.0000 | |
| SRP008496 | SYT11 | 23208 | RNAseq | 1.9200 | 0.0000 | |
| SRP064894 | SYT11 | 23208 | RNAseq | 0.3261 | 0.2392 | |
| SRP133303 | SYT11 | 23208 | RNAseq | 0.0729 | 0.7312 | |
| SRP159526 | SYT11 | 23208 | RNAseq | 0.3478 | 0.3416 | |
| SRP193095 | SYT11 | 23208 | RNAseq | 0.7280 | 0.0000 | |
| SRP219564 | SYT11 | 23208 | RNAseq | 0.0324 | 0.9685 | |
| TCGA | SYT11 | 23208 | RNAseq | -0.3668 | 0.0072 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by SYT11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYT11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT11 | 23208 | 14 | 0 | 16 | |
| GSE20123 | SYT11 | 23208 | 13 | 0 | 17 | |
| GSE43470 | SYT11 | 23208 | 7 | 2 | 34 | |
| GSE46452 | SYT11 | 23208 | 2 | 1 | 56 | |
| GSE47630 | SYT11 | 23208 | 14 | 0 | 26 | |
| GSE54993 | SYT11 | 23208 | 0 | 5 | 65 | |
| GSE54994 | SYT11 | 23208 | 16 | 0 | 37 | |
| GSE60625 | SYT11 | 23208 | 0 | 0 | 11 | |
| GSE74703 | SYT11 | 23208 | 7 | 2 | 27 | |
| GSE74704 | SYT11 | 23208 | 6 | 0 | 14 | |
| TCGA | SYT11 | 23208 | 38 | 2 | 56 |
Total number of gains: 117; Total number of losses: 12; Total Number of normals: 359.
Somatic mutations of SYT11:
Generating mutation plots.
Highly correlated genes for SYT11:
Showing top 20/944 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT11 | DNM3OS | 0.800111 | 3 | 0 | 3 |
| SYT11 | NAP1L3 | 0.768617 | 9 | 0 | 9 |
| SYT11 | ZCCHC18 | 0.764575 | 3 | 0 | 3 |
| SYT11 | PABPC5 | 0.761898 | 5 | 0 | 5 |
| SYT11 | LINC01279 | 0.744266 | 3 | 0 | 3 |
| SYT11 | FIBIN | 0.744137 | 4 | 0 | 3 |
| SYT11 | MAGI2-AS3 | 0.727388 | 5 | 0 | 4 |
| SYT11 | PEAK1 | 0.723926 | 7 | 0 | 6 |
| SYT11 | GALNT15 | 0.718743 | 5 | 0 | 5 |
| SYT11 | FAT4 | 0.716913 | 7 | 0 | 5 |
| SYT11 | CLIP3 | 0.716042 | 10 | 0 | 9 |
| SYT11 | PARVA | 0.707577 | 7 | 0 | 7 |
| SYT11 | CPQ | 0.706861 | 9 | 0 | 8 |
| SYT11 | SYNE1 | 0.706687 | 9 | 0 | 8 |
| SYT11 | ANK2 | 0.702491 | 8 | 0 | 7 |
| SYT11 | KCNJ8 | 0.700488 | 12 | 0 | 10 |
| SYT11 | CNRIP1 | 0.695634 | 7 | 0 | 5 |
| SYT11 | SMIM20 | 0.694646 | 3 | 0 | 3 |
| SYT11 | LRCH2 | 0.694367 | 7 | 0 | 6 |
| SYT11 | ACTC1 | 0.69402 | 6 | 0 | 6 |
For details and further investigation, click here
