PCDH9

 

Full name: protocadherin 9 Alias Symbol: 
Type: protein-coding gene Cytoband: 13q21.32
Entrez ID: 5101 HGNC ID: HGNC:8661 Ensembl Gene: ENSG00000184226 OMIM ID: 603581
Drug and gene relationship at DGIdb

 

Expression of PCDH9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PCDH9 5101 219737_s_at -1.0950 0.5682
GSE20347 PCDH9 5101 219737_s_at 0.1583 0.6172
GSE23400 PCDH9 5101 219737_s_at -0.5105 0.0010
GSE26886 PCDH9 5101 219737_s_at 0.3780 0.0497
GSE29001 PCDH9 5101 219737_s_at -0.1978 0.7409
GSE38129 PCDH9 5101 219737_s_at -0.9152 0.0478
GSE45670 PCDH9 5101 219737_s_at -1.7960 0.0000
GSE53622 PCDH9 5101 45517 -1.5452 0.0000
GSE53624 PCDH9 5101 45517 -1.6579 0.0000
GSE63941 PCDH9 5101 219737_s_at -3.7881 0.0002
GSE77861 PCDH9 5101 219737_s_at 0.1238 0.3073
GSE97050 PCDH9 5101 A_33_P3236661 -0.9420 0.1584
SRP007169 PCDH9 5101 RNAseq 3.6136 0.0001
SRP064894 PCDH9 5101 RNAseq 0.6179 0.1452
SRP133303 PCDH9 5101 RNAseq -0.9729 0.0012
SRP159526 PCDH9 5101 RNAseq 0.6241 0.3550
SRP193095 PCDH9 5101 RNAseq 1.3464 0.0006
SRP219564 PCDH9 5101 RNAseq -0.2211 0.8481
TCGA PCDH9 5101 RNAseq -1.5980 0.0001

Upregulated datasets: 2; Downregulated datasets: 5.  


 

Survival by PCDH9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PCDH9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PCDH9 5101 3 13 14
GSE20123 PCDH9 5101 3 12 15
GSE43470 PCDH9 5101 2 12 29
GSE46452 PCDH9 5101 0 32 27
GSE47630 PCDH9 5101 3 26 11
GSE54993 PCDH9 5101 11 3 56
GSE54994 PCDH9 5101 3 12 38
GSE60625 PCDH9 5101 0 3 8
GSE74703 PCDH9 5101 1 10 25
GSE74704 PCDH9 5101 1 11 8
TCGA PCDH9 5101 12 34 50

Total number of gains: 39; Total number of losses: 168; Total Number of normals: 281.  


 

Somatic mutations of PCDH9:

 

Generating mutation plots.

 

Highly correlated genes for PCDH9:

 

Showing top 20/1033 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PCDH9CNTN30.87457303
PCDH9MAP1A0.833515606
PCDH9KIRREL30.822258303
PCDH9ZNF6600.814788303
PCDH9ADAMTSL10.81302505
PCDH9TBX5-AS10.806876404
PCDH9SHISA30.802317404
PCDH9RBM240.788708505
PCDH9PABPC50.784682403
PCDH9LRCH10.783759404
PCDH9LRRN4CL0.781817606
PCDH9FLNC0.781471908
PCDH9OMD0.779322606
PCDH9NEGR10.776896605
PCDH9NEXN0.775131606
PCDH9EPM2A0.774236505
PCDH9HSPB70.76762909
PCDH9SGCD0.765831707
PCDH9FGL20.765064808
PCDH9NFASC0.761491606

For details and further investigation, click here