| Full name: crystallin beta B1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q12.1 | ||
| Entrez ID: 1414 | HGNC ID: HGNC:2397 | Ensembl Gene: ENSG00000100122 | OMIM ID: 600929 |
| Drug and gene relationship at DGIdb | |||
Expression of CRYBB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRYBB1 | 1414 | 206185_at | -0.0616 | 0.7852 | |
| GSE20347 | CRYBB1 | 1414 | 206185_at | -0.1743 | 0.0337 | |
| GSE23400 | CRYBB1 | 1414 | 206185_at | -0.1744 | 0.0000 | |
| GSE26886 | CRYBB1 | 1414 | 206185_at | 0.2270 | 0.1207 | |
| GSE29001 | CRYBB1 | 1414 | 206185_at | -0.1714 | 0.3162 | |
| GSE38129 | CRYBB1 | 1414 | 206185_at | -0.1408 | 0.2160 | |
| GSE45670 | CRYBB1 | 1414 | 206185_at | 0.0119 | 0.9276 | |
| GSE53622 | CRYBB1 | 1414 | 4000 | 0.1818 | 0.0281 | |
| GSE53624 | CRYBB1 | 1414 | 4000 | 0.0209 | 0.8279 | |
| GSE63941 | CRYBB1 | 1414 | 206185_at | 0.1158 | 0.4328 | |
| GSE77861 | CRYBB1 | 1414 | 206185_at | -0.0460 | 0.7843 | |
| GSE97050 | CRYBB1 | 1414 | A_23_P143621 | -0.1966 | 0.6635 | |
| TCGA | CRYBB1 | 1414 | RNAseq | 0.2966 | 0.6199 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRYBB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRYBB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRYBB1 | 1414 | 3 | 5 | 22 | |
| GSE20123 | CRYBB1 | 1414 | 3 | 4 | 23 | |
| GSE43470 | CRYBB1 | 1414 | 4 | 6 | 33 | |
| GSE46452 | CRYBB1 | 1414 | 31 | 1 | 27 | |
| GSE47630 | CRYBB1 | 1414 | 8 | 5 | 27 | |
| GSE54993 | CRYBB1 | 1414 | 3 | 6 | 61 | |
| GSE54994 | CRYBB1 | 1414 | 11 | 8 | 34 | |
| GSE60625 | CRYBB1 | 1414 | 5 | 0 | 6 | |
| GSE74703 | CRYBB1 | 1414 | 3 | 5 | 28 | |
| GSE74704 | CRYBB1 | 1414 | 0 | 1 | 19 | |
| TCGA | CRYBB1 | 1414 | 26 | 14 | 56 |
Total number of gains: 97; Total number of losses: 55; Total Number of normals: 336.
Somatic mutations of CRYBB1:
Generating mutation plots.
Highly correlated genes for CRYBB1:
Showing top 20/1170 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRYBB1 | CELF5 | 0.779866 | 3 | 0 | 3 |
| CRYBB1 | PLA2G2C | 0.764043 | 3 | 0 | 3 |
| CRYBB1 | DEFB121 | 0.75995 | 3 | 0 | 3 |
| CRYBB1 | OR2T27 | 0.757767 | 3 | 0 | 3 |
| CRYBB1 | STRC | 0.75198 | 3 | 0 | 3 |
| CRYBB1 | OR10AD1 | 0.748936 | 3 | 0 | 3 |
| CRYBB1 | FBRSL1 | 0.748027 | 3 | 0 | 3 |
| CRYBB1 | TAS2R40 | 0.743205 | 3 | 0 | 3 |
| CRYBB1 | CYLC1 | 0.739288 | 4 | 0 | 4 |
| CRYBB1 | C6orf223 | 0.725032 | 3 | 0 | 3 |
| CRYBB1 | YY2 | 0.72476 | 3 | 0 | 3 |
| CRYBB1 | FUT9 | 0.716867 | 3 | 0 | 3 |
| CRYBB1 | CECR9 | 0.716421 | 3 | 0 | 3 |
| CRYBB1 | OR2A5 | 0.715462 | 3 | 0 | 3 |
| CRYBB1 | KRTAP10-12 | 0.714392 | 3 | 0 | 3 |
| CRYBB1 | DCDC1 | 0.714382 | 3 | 0 | 3 |
| CRYBB1 | KCP | 0.713706 | 4 | 0 | 4 |
| CRYBB1 | C3orf36 | 0.712536 | 6 | 0 | 6 |
| CRYBB1 | BTNL2 | 0.711494 | 9 | 0 | 8 |
| CRYBB1 | CHST13 | 0.7075 | 5 | 0 | 5 |
For details and further investigation, click here
