| Full name: fibrosin like 1 | Alias Symbol: KIAA1545 | ||
| Type: protein-coding gene | Cytoband: 12q24.33 | ||
| Entrez ID: 57666 | HGNC ID: HGNC:29308 | Ensembl Gene: ENSG00000112787 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FBRSL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBRSL1 | 57666 | 225703_at | 0.9733 | 0.1750 | |
| GSE26886 | FBRSL1 | 57666 | 225703_at | 1.5210 | 0.0000 | |
| GSE45670 | FBRSL1 | 57666 | 225703_at | 0.6603 | 0.0074 | |
| GSE53622 | FBRSL1 | 57666 | 86637 | 0.1027 | 0.1415 | |
| GSE53624 | FBRSL1 | 57666 | 86637 | 0.1327 | 0.1357 | |
| GSE63941 | FBRSL1 | 57666 | 225703_at | 0.0667 | 0.8939 | |
| GSE77861 | FBRSL1 | 57666 | 225703_at | 1.2215 | 0.0023 | |
| GSE97050 | FBRSL1 | 57666 | A_24_P280497 | -0.1174 | 0.5556 | |
| SRP007169 | FBRSL1 | 57666 | RNAseq | 2.2343 | 0.0006 | |
| SRP008496 | FBRSL1 | 57666 | RNAseq | 1.7930 | 0.0001 | |
| SRP064894 | FBRSL1 | 57666 | RNAseq | 0.2677 | 0.1545 | |
| SRP133303 | FBRSL1 | 57666 | RNAseq | 0.0743 | 0.5904 | |
| SRP159526 | FBRSL1 | 57666 | RNAseq | 0.8934 | 0.0258 | |
| SRP193095 | FBRSL1 | 57666 | RNAseq | 0.8427 | 0.0000 | |
| SRP219564 | FBRSL1 | 57666 | RNAseq | 0.1238 | 0.7552 | |
| TCGA | FBRSL1 | 57666 | RNAseq | -0.0321 | 0.5092 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by FBRSL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBRSL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBRSL1 | 57666 | 4 | 5 | 21 | |
| GSE20123 | FBRSL1 | 57666 | 4 | 5 | 21 | |
| GSE43470 | FBRSL1 | 57666 | 3 | 3 | 37 | |
| GSE46452 | FBRSL1 | 57666 | 8 | 3 | 48 | |
| GSE47630 | FBRSL1 | 57666 | 9 | 3 | 28 | |
| GSE54993 | FBRSL1 | 57666 | 0 | 6 | 64 | |
| GSE54994 | FBRSL1 | 57666 | 4 | 8 | 41 | |
| GSE60625 | FBRSL1 | 57666 | 1 | 0 | 10 | |
| GSE74703 | FBRSL1 | 57666 | 2 | 3 | 31 | |
| GSE74704 | FBRSL1 | 57666 | 2 | 3 | 15 | |
| TCGA | FBRSL1 | 57666 | 21 | 15 | 60 |
Total number of gains: 58; Total number of losses: 54; Total Number of normals: 376.
Somatic mutations of FBRSL1:
Generating mutation plots.
Highly correlated genes for FBRSL1:
Showing top 20/641 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBRSL1 | SHARPIN | 0.910967 | 3 | 0 | 3 |
| FBRSL1 | GRIK4 | 0.896603 | 3 | 0 | 3 |
| FBRSL1 | STRC | 0.896042 | 3 | 0 | 3 |
| FBRSL1 | DCDC1 | 0.882404 | 3 | 0 | 3 |
| FBRSL1 | GH1 | 0.873795 | 3 | 0 | 3 |
| FBRSL1 | FOXE3 | 0.869305 | 3 | 0 | 3 |
| FBRSL1 | PLA2G2C | 0.864627 | 3 | 0 | 3 |
| FBRSL1 | SHISA7 | 0.854816 | 3 | 0 | 3 |
| FBRSL1 | LRIT1 | 0.854549 | 3 | 0 | 3 |
| FBRSL1 | MRGPRG | 0.846557 | 3 | 0 | 3 |
| FBRSL1 | C2CD4D | 0.844479 | 3 | 0 | 3 |
| FBRSL1 | C19orf44 | 0.843972 | 4 | 0 | 4 |
| FBRSL1 | PLA2G2D | 0.842299 | 3 | 0 | 3 |
| FBRSL1 | CD72 | 0.839931 | 3 | 0 | 3 |
| FBRSL1 | SLC18A3 | 0.839104 | 3 | 0 | 3 |
| FBRSL1 | YY2 | 0.837929 | 3 | 0 | 3 |
| FBRSL1 | C9orf153 | 0.83782 | 3 | 0 | 3 |
| FBRSL1 | TTC12 | 0.835346 | 3 | 0 | 3 |
| FBRSL1 | CA6 | 0.828895 | 3 | 0 | 3 |
| FBRSL1 | LBX2 | 0.828183 | 3 | 0 | 3 |
For details and further investigation, click here
