| Full name: crystallin zeta like 1 | Alias Symbol: QOH-1|4P11 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 9946 | HGNC ID: HGNC:2420 | Ensembl Gene: ENSG00000205758 | OMIM ID: 603920 |
| Drug and gene relationship at DGIdb | |||
Expression of CRYZL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRYZL1 | 9946 | 226151_x_at | -0.6451 | 0.1127 | |
| GSE20347 | CRYZL1 | 9946 | 219767_s_at | -0.6742 | 0.0000 | |
| GSE23400 | CRYZL1 | 9946 | 219767_s_at | -0.1602 | 0.0793 | |
| GSE26886 | CRYZL1 | 9946 | 226151_x_at | -0.1904 | 0.4209 | |
| GSE29001 | CRYZL1 | 9946 | 219767_s_at | -0.2307 | 0.6257 | |
| GSE38129 | CRYZL1 | 9946 | 219767_s_at | -0.8579 | 0.0000 | |
| GSE45670 | CRYZL1 | 9946 | 226151_x_at | -0.7497 | 0.0000 | |
| GSE53622 | CRYZL1 | 9946 | 99171 | -0.5168 | 0.0000 | |
| GSE53624 | CRYZL1 | 9946 | 99171 | -0.5334 | 0.0000 | |
| GSE63941 | CRYZL1 | 9946 | 226151_x_at | -0.4469 | 0.2642 | |
| GSE77861 | CRYZL1 | 9946 | 226151_x_at | -0.5605 | 0.0384 | |
| GSE97050 | CRYZL1 | 9946 | A_23_P218731 | -0.6182 | 0.1074 | |
| SRP007169 | CRYZL1 | 9946 | RNAseq | -1.4166 | 0.0003 | |
| SRP008496 | CRYZL1 | 9946 | RNAseq | -0.9066 | 0.0003 | |
| SRP064894 | CRYZL1 | 9946 | RNAseq | -0.3587 | 0.0167 | |
| SRP133303 | CRYZL1 | 9946 | RNAseq | -0.6268 | 0.0042 | |
| SRP159526 | CRYZL1 | 9946 | RNAseq | -0.5198 | 0.0443 | |
| SRP193095 | CRYZL1 | 9946 | RNAseq | -0.4519 | 0.0000 | |
| SRP219564 | CRYZL1 | 9946 | RNAseq | -0.7891 | 0.0683 | |
| TCGA | CRYZL1 | 9946 | RNAseq | -0.2722 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CRYZL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRYZL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRYZL1 | 9946 | 2 | 8 | 20 | |
| GSE20123 | CRYZL1 | 9946 | 2 | 9 | 19 | |
| GSE43470 | CRYZL1 | 9946 | 3 | 9 | 31 | |
| GSE46452 | CRYZL1 | 9946 | 1 | 21 | 37 | |
| GSE47630 | CRYZL1 | 9946 | 6 | 17 | 17 | |
| GSE54993 | CRYZL1 | 9946 | 9 | 1 | 60 | |
| GSE54994 | CRYZL1 | 9946 | 1 | 9 | 43 | |
| GSE60625 | CRYZL1 | 9946 | 0 | 0 | 11 | |
| GSE74703 | CRYZL1 | 9946 | 3 | 6 | 27 | |
| GSE74704 | CRYZL1 | 9946 | 1 | 4 | 15 | |
| TCGA | CRYZL1 | 9946 | 9 | 35 | 52 |
Total number of gains: 37; Total number of losses: 119; Total Number of normals: 332.
Somatic mutations of CRYZL1:
Generating mutation plots.
Highly correlated genes for CRYZL1:
Showing top 20/1271 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRYZL1 | NDUFV3 | 0.777265 | 3 | 0 | 3 |
| CRYZL1 | C1QTNF7 | 0.77446 | 5 | 0 | 5 |
| CRYZL1 | TMEM132C | 0.768883 | 3 | 0 | 3 |
| CRYZL1 | RNASE4 | 0.752568 | 6 | 0 | 6 |
| CRYZL1 | ANO5 | 0.749642 | 5 | 0 | 5 |
| CRYZL1 | PLP1 | 0.747048 | 7 | 0 | 7 |
| CRYZL1 | RAB9B | 0.743988 | 5 | 0 | 5 |
| CRYZL1 | ZMAT1 | 0.740229 | 5 | 0 | 5 |
| CRYZL1 | JAM2 | 0.73958 | 8 | 0 | 8 |
| CRYZL1 | FIBIN | 0.732646 | 4 | 0 | 4 |
| CRYZL1 | XKR4 | 0.730922 | 5 | 0 | 5 |
| CRYZL1 | SLC30A5 | 0.730175 | 4 | 0 | 4 |
| CRYZL1 | GPRASP1 | 0.729919 | 7 | 0 | 7 |
| CRYZL1 | ZCWPW2 | 0.720194 | 4 | 0 | 4 |
| CRYZL1 | ANGPTL1 | 0.72016 | 6 | 0 | 5 |
| CRYZL1 | MOAP1 | 0.71943 | 7 | 0 | 7 |
| CRYZL1 | SNTB1 | 0.717044 | 6 | 0 | 6 |
| CRYZL1 | FBXO8 | 0.714515 | 5 | 0 | 5 |
| CRYZL1 | TCEAL6 | 0.714111 | 3 | 0 | 3 |
| CRYZL1 | FAM13C | 0.710049 | 5 | 0 | 4 |
For details and further investigation, click here
