| Full name: transmembrane protein 132C | Alias Symbol: DKFZp761O2018|PPP1R152 | ||
| Type: protein-coding gene | Cytoband: 12q24.32 | ||
| Entrez ID: 92293 | HGNC ID: HGNC:25436 | Ensembl Gene: ENSG00000181234 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM132C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM132C | 92293 | 232313_at | -0.5975 | 0.0858 | |
| GSE26886 | TMEM132C | 92293 | 232313_at | 0.3720 | 0.2568 | |
| GSE45670 | TMEM132C | 92293 | 232313_at | -1.6601 | 0.0000 | |
| GSE53622 | TMEM132C | 92293 | 49074 | -0.0932 | 0.5708 | |
| GSE53624 | TMEM132C | 92293 | 49074 | -0.1855 | 0.2343 | |
| GSE63941 | TMEM132C | 92293 | 232313_at | 0.2117 | 0.1111 | |
| GSE77861 | TMEM132C | 92293 | 232313_at | 0.0287 | 0.7815 | |
| GSE97050 | TMEM132C | 92293 | A_23_P151232 | -0.0314 | 0.9551 | |
| SRP064894 | TMEM132C | 92293 | RNAseq | -2.8319 | 0.0000 | |
| SRP133303 | TMEM132C | 92293 | RNAseq | -3.9892 | 0.0000 | |
| SRP159526 | TMEM132C | 92293 | RNAseq | -0.2259 | 0.8608 | |
| SRP219564 | TMEM132C | 92293 | RNAseq | -2.0204 | 0.0688 | |
| TCGA | TMEM132C | 92293 | RNAseq | -2.8234 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TMEM132C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM132C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM132C | 92293 | 3 | 4 | 23 | |
| GSE20123 | TMEM132C | 92293 | 3 | 4 | 23 | |
| GSE43470 | TMEM132C | 92293 | 2 | 0 | 41 | |
| GSE46452 | TMEM132C | 92293 | 9 | 1 | 49 | |
| GSE47630 | TMEM132C | 92293 | 9 | 3 | 28 | |
| GSE54993 | TMEM132C | 92293 | 0 | 5 | 65 | |
| GSE54994 | TMEM132C | 92293 | 4 | 7 | 42 | |
| GSE60625 | TMEM132C | 92293 | 0 | 0 | 11 | |
| GSE74703 | TMEM132C | 92293 | 2 | 0 | 34 | |
| GSE74704 | TMEM132C | 92293 | 2 | 3 | 15 | |
| TCGA | TMEM132C | 92293 | 22 | 13 | 61 |
Total number of gains: 56; Total number of losses: 40; Total Number of normals: 392.
Somatic mutations of TMEM132C:
Generating mutation plots.
Highly correlated genes for TMEM132C:
Showing top 20/331 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM132C | TMSB4Y | 0.791914 | 3 | 0 | 3 |
| TMEM132C | FNBP1 | 0.787453 | 3 | 0 | 3 |
| TMEM132C | ITPR1 | 0.781212 | 3 | 0 | 3 |
| TMEM132C | TSPYL4 | 0.77873 | 3 | 0 | 3 |
| TMEM132C | CASQ2 | 0.778202 | 3 | 0 | 3 |
| TMEM132C | FAM172A | 0.77685 | 3 | 0 | 3 |
| TMEM132C | UFSP2 | 0.77225 | 3 | 0 | 3 |
| TMEM132C | RAP1A | 0.769801 | 3 | 0 | 3 |
| TMEM132C | MEF2D | 0.769027 | 3 | 0 | 3 |
| TMEM132C | CRYZL1 | 0.768883 | 3 | 0 | 3 |
| TMEM132C | SPAG8 | 0.768776 | 3 | 0 | 3 |
| TMEM132C | KCNAB1 | 0.768191 | 3 | 0 | 3 |
| TMEM132C | CRBN | 0.766625 | 3 | 0 | 3 |
| TMEM132C | REV3L | 0.765908 | 3 | 0 | 3 |
| TMEM132C | SIRT1 | 0.759712 | 3 | 0 | 3 |
| TMEM132C | KIAA1191 | 0.756583 | 3 | 0 | 3 |
| TMEM132C | NDUFB8 | 0.756187 | 3 | 0 | 3 |
| TMEM132C | PDCD4 | 0.754993 | 3 | 0 | 3 |
| TMEM132C | SOCS2 | 0.754353 | 3 | 0 | 3 |
| TMEM132C | ACAT1 | 0.750795 | 3 | 0 | 3 |
For details and further investigation, click here
