| Full name: anoctamin 5 | Alias Symbol: GDD1 | ||
| Type: protein-coding gene | Cytoband: 11p14.3 | ||
| Entrez ID: 203859 | HGNC ID: HGNC:27337 | Ensembl Gene: ENSG00000171714 | OMIM ID: 608662 |
| Drug and gene relationship at DGIdb | |||
Expression of ANO5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANO5 | 203859 | 229313_at | -1.2360 | 0.2621 | |
| GSE26886 | ANO5 | 203859 | 229313_at | 0.0381 | 0.8815 | |
| GSE45670 | ANO5 | 203859 | 229313_at | -1.3845 | 0.0000 | |
| GSE53622 | ANO5 | 203859 | 80873 | -2.3133 | 0.0000 | |
| GSE53624 | ANO5 | 203859 | 80873 | -2.2621 | 0.0000 | |
| GSE63941 | ANO5 | 203859 | 229313_at | -1.2143 | 0.0092 | |
| GSE77861 | ANO5 | 203859 | 229313_at | -0.0172 | 0.8824 | |
| GSE97050 | ANO5 | 203859 | A_24_P100996 | -0.6317 | 0.2494 | |
| SRP064894 | ANO5 | 203859 | RNAseq | -0.3742 | 0.4178 | |
| SRP133303 | ANO5 | 203859 | RNAseq | -1.8883 | 0.0000 | |
| SRP159526 | ANO5 | 203859 | RNAseq | -0.6284 | 0.2370 | |
| SRP219564 | ANO5 | 203859 | RNAseq | -0.7955 | 0.4800 | |
| TCGA | ANO5 | 203859 | RNAseq | -1.8208 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ANO5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANO5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANO5 | 203859 | 0 | 11 | 19 | |
| GSE20123 | ANO5 | 203859 | 0 | 11 | 19 | |
| GSE43470 | ANO5 | 203859 | 1 | 6 | 36 | |
| GSE46452 | ANO5 | 203859 | 7 | 5 | 47 | |
| GSE47630 | ANO5 | 203859 | 3 | 10 | 27 | |
| GSE54993 | ANO5 | 203859 | 3 | 0 | 67 | |
| GSE54994 | ANO5 | 203859 | 3 | 12 | 38 | |
| GSE60625 | ANO5 | 203859 | 0 | 0 | 11 | |
| GSE74703 | ANO5 | 203859 | 1 | 4 | 31 | |
| GSE74704 | ANO5 | 203859 | 0 | 9 | 11 | |
| TCGA | ANO5 | 203859 | 12 | 24 | 60 |
Total number of gains: 30; Total number of losses: 92; Total Number of normals: 366.
Somatic mutations of ANO5:
Generating mutation plots.
Highly correlated genes for ANO5:
Showing top 20/1130 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANO5 | SORCS1 | 0.896959 | 4 | 0 | 4 |
| ANO5 | NCAM1 | 0.882095 | 5 | 0 | 5 |
| ANO5 | XKR4 | 0.851815 | 5 | 0 | 5 |
| ANO5 | ITGA7 | 0.850186 | 5 | 0 | 5 |
| ANO5 | CACNB2 | 0.845549 | 5 | 0 | 5 |
| ANO5 | KIAA0408 | 0.834065 | 3 | 0 | 3 |
| ANO5 | DTNA | 0.8208 | 4 | 0 | 4 |
| ANO5 | HSPA12A | 0.814951 | 3 | 0 | 3 |
| ANO5 | NME5 | 0.814622 | 6 | 0 | 6 |
| ANO5 | PGR | 0.811971 | 6 | 0 | 6 |
| ANO5 | CTNNA3 | 0.810766 | 5 | 0 | 5 |
| ANO5 | PARD3B | 0.807669 | 5 | 0 | 5 |
| ANO5 | SYNM | 0.806453 | 5 | 0 | 5 |
| ANO5 | CADM2 | 0.80435 | 4 | 0 | 4 |
| ANO5 | HPSE2 | 0.804324 | 5 | 0 | 5 |
| ANO5 | ANGPTL1 | 0.803519 | 6 | 0 | 6 |
| ANO5 | ARHGAP6 | 0.803495 | 6 | 0 | 6 |
| ANO5 | CYP21A2 | 0.802938 | 3 | 0 | 3 |
| ANO5 | FAM184A | 0.801041 | 4 | 0 | 4 |
| ANO5 | PLA2G5 | 0.799748 | 4 | 0 | 4 |
For details and further investigation, click here
