PLP1

 

Full name: proteolipid protein 1 Alias Symbol: GPM6C
Type: protein-coding gene Cytoband: Xq22.2
Entrez ID: 5354 HGNC ID: HGNC:9086 Ensembl Gene: ENSG00000123560 OMIM ID: 300401
Drug and gene relationship at DGIdb

 

Expression of PLP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PLP1 5354 210198_s_at -2.3861 0.1143
GSE20347 PLP1 5354 210198_s_at -0.8322 0.0022
GSE23400 PLP1 5354 210198_s_at -0.4805 0.0001
GSE26886 PLP1 5354 210198_s_at 0.1597 0.4687
GSE29001 PLP1 5354 210198_s_at -0.7626 0.0116
GSE38129 PLP1 5354 210198_s_at -1.9209 0.0000
GSE45670 PLP1 5354 210198_s_at -3.3337 0.0000
GSE53622 PLP1 5354 7584 -1.1097 0.0000
GSE53624 PLP1 5354 7584 -1.3007 0.0000
GSE63941 PLP1 5354 210198_s_at -0.0595 0.7019
GSE77861 PLP1 5354 210198_s_at 0.0281 0.7260
GSE97050 PLP1 5354 A_33_P3334630 -0.7696 0.1733
SRP064894 PLP1 5354 RNAseq -1.1865 0.0258
SRP133303 PLP1 5354 RNAseq -2.1738 0.0099
SRP159526 PLP1 5354 RNAseq -2.3098 0.0000
TCGA PLP1 5354 RNAseq -2.1088 0.0002

Upregulated datasets: 0; Downregulated datasets: 8.  

 

Survival by PLP1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PLP1:

 

No record found for this gene.

 

Somatic mutations of PLP1:

 

Generating mutation plots.

 

Highly correlated genes for PLP1:

 

Showing top 20/1167 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PLP1EPM2A0.826743505
PLP1MYOCD0.824378606
PLP1SLIT20.80594707
PLP1MYOC0.803162909
PLP1MAMDC20.796485505
PLP1LMOD10.79247511011
PLP1CASQ20.78906810010
PLP1PDZRN40.78657810010
PLP1ARHGAP60.785877908
PLP1PEG30.78417707
PLP1CDH190.778994908
PLP1DAAM20.7743781009
PLP1CCDC690.773791909
PLP1CHRDL10.77281009
PLP1LINC012790.770906303
PLP1VMAC0.76959303
PLP1BHMT20.769078908
PLP1ANGPTL10.768696606
PLP1ABCA80.768691909
PLP1SVEP10.766795505

For details and further investigation, click here