| Full name: modulator of apoptosis 1 | Alias Symbol: MAP-1|PNMA4 | ||
| Type: protein-coding gene | Cytoband: 14q32.12 | ||
| Entrez ID: 64112 | HGNC ID: HGNC:16658 | Ensembl Gene: ENSG00000165943 | OMIM ID: 609485 |
| Drug and gene relationship at DGIdb | |||
Expression of MOAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOAP1 | 64112 | 212508_at | -0.7434 | 0.2152 | |
| GSE20347 | MOAP1 | 64112 | 212508_at | -0.0124 | 0.9541 | |
| GSE23400 | MOAP1 | 64112 | 212508_at | 0.0545 | 0.6908 | |
| GSE26886 | MOAP1 | 64112 | 212508_at | 0.8241 | 0.0001 | |
| GSE29001 | MOAP1 | 64112 | 212508_at | 0.2696 | 0.3179 | |
| GSE38129 | MOAP1 | 64112 | 212508_at | -0.2528 | 0.3843 | |
| GSE45670 | MOAP1 | 64112 | 212508_at | -0.8608 | 0.0000 | |
| GSE53622 | MOAP1 | 64112 | 31427 | -0.5612 | 0.0000 | |
| GSE53624 | MOAP1 | 64112 | 31427 | -0.5968 | 0.0000 | |
| GSE63941 | MOAP1 | 64112 | 212508_at | -0.2156 | 0.6837 | |
| GSE77861 | MOAP1 | 64112 | 212508_at | 0.3242 | 0.3592 | |
| GSE97050 | MOAP1 | 64112 | A_23_P205389 | -0.4565 | 0.2544 | |
| SRP007169 | MOAP1 | 64112 | RNAseq | 0.8481 | 0.1153 | |
| SRP008496 | MOAP1 | 64112 | RNAseq | 0.7699 | 0.0419 | |
| SRP064894 | MOAP1 | 64112 | RNAseq | -0.6205 | 0.0002 | |
| SRP133303 | MOAP1 | 64112 | RNAseq | -0.3786 | 0.0566 | |
| SRP159526 | MOAP1 | 64112 | RNAseq | -0.1600 | 0.3970 | |
| SRP193095 | MOAP1 | 64112 | RNAseq | 0.0988 | 0.4839 | |
| SRP219564 | MOAP1 | 64112 | RNAseq | -0.8759 | 0.0689 | |
| TCGA | MOAP1 | 64112 | RNAseq | -0.4094 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MOAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOAP1 | 64112 | 8 | 5 | 17 | |
| GSE20123 | MOAP1 | 64112 | 8 | 4 | 18 | |
| GSE43470 | MOAP1 | 64112 | 7 | 3 | 33 | |
| GSE46452 | MOAP1 | 64112 | 16 | 3 | 40 | |
| GSE47630 | MOAP1 | 64112 | 11 | 8 | 21 | |
| GSE54993 | MOAP1 | 64112 | 3 | 8 | 59 | |
| GSE54994 | MOAP1 | 64112 | 20 | 4 | 29 | |
| GSE60625 | MOAP1 | 64112 | 0 | 2 | 9 | |
| GSE74703 | MOAP1 | 64112 | 6 | 3 | 27 | |
| GSE74704 | MOAP1 | 64112 | 4 | 3 | 13 | |
| TCGA | MOAP1 | 64112 | 29 | 21 | 46 |
Total number of gains: 112; Total number of losses: 64; Total Number of normals: 312.
Somatic mutations of MOAP1:
Generating mutation plots.
Highly correlated genes for MOAP1:
Showing top 20/1108 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOAP1 | NEGR1 | 0.796835 | 5 | 0 | 5 |
| MOAP1 | PDE4DIP | 0.796416 | 3 | 0 | 3 |
| MOAP1 | ANO5 | 0.791276 | 5 | 0 | 5 |
| MOAP1 | IQUB | 0.782288 | 3 | 0 | 3 |
| MOAP1 | CLASP1 | 0.777317 | 3 | 0 | 3 |
| MOAP1 | SORCS1 | 0.769926 | 4 | 0 | 4 |
| MOAP1 | TCEAL1 | 0.769546 | 11 | 0 | 11 |
| MOAP1 | ZNF354A | 0.767647 | 3 | 0 | 3 |
| MOAP1 | MRPS6 | 0.759515 | 3 | 0 | 3 |
| MOAP1 | SGCD | 0.758283 | 6 | 0 | 6 |
| MOAP1 | ASB5 | 0.756784 | 5 | 0 | 5 |
| MOAP1 | CBX7 | 0.754555 | 7 | 0 | 7 |
| MOAP1 | DCAF8 | 0.754162 | 4 | 0 | 4 |
| MOAP1 | ZNF609 | 0.751784 | 3 | 0 | 3 |
| MOAP1 | BOD1 | 0.747016 | 3 | 0 | 3 |
| MOAP1 | SPOP | 0.746054 | 6 | 0 | 6 |
| MOAP1 | RP9 | 0.745611 | 3 | 0 | 3 |
| MOAP1 | KLHL23 | 0.745611 | 4 | 0 | 4 |
| MOAP1 | ZFP90 | 0.745169 | 3 | 0 | 3 |
| MOAP1 | LRRN4CL | 0.743528 | 5 | 0 | 5 |
For details and further investigation, click here
