| Full name: XK related 4 | Alias Symbol: KIAA1889 | ||
| Type: protein-coding gene | Cytoband: 8q12.1 | ||
| Entrez ID: 114786 | HGNC ID: HGNC:29394 | Ensembl Gene: ENSG00000206579 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of XKR4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XKR4 | 114786 | 237802_at | -1.3194 | 0.1778 | |
| GSE26886 | XKR4 | 114786 | 237802_at | 0.1376 | 0.6528 | |
| GSE45670 | XKR4 | 114786 | 237802_at | -1.0392 | 0.0000 | |
| GSE53622 | XKR4 | 114786 | 75896 | -2.5355 | 0.0000 | |
| GSE53624 | XKR4 | 114786 | 75896 | -3.3348 | 0.0000 | |
| GSE63941 | XKR4 | 114786 | 237802_at | -0.0150 | 0.9143 | |
| GSE77861 | XKR4 | 114786 | 237802_at | 0.0374 | 0.7058 | |
| GSE97050 | XKR4 | 114786 | A_32_P134007 | -1.4228 | 0.1235 | |
| SRP064894 | XKR4 | 114786 | RNAseq | -0.6566 | 0.1031 | |
| SRP133303 | XKR4 | 114786 | RNAseq | -0.8938 | 0.0009 | |
| SRP159526 | XKR4 | 114786 | RNAseq | -1.7216 | 0.0000 | |
| SRP193095 | XKR4 | 114786 | RNAseq | -0.1480 | 0.4607 | |
| TCGA | XKR4 | 114786 | RNAseq | -2.3544 | 0.0034 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by XKR4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XKR4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XKR4 | 114786 | 14 | 1 | 15 | |
| GSE20123 | XKR4 | 114786 | 14 | 1 | 15 | |
| GSE43470 | XKR4 | 114786 | 13 | 3 | 27 | |
| GSE46452 | XKR4 | 114786 | 20 | 3 | 36 | |
| GSE47630 | XKR4 | 114786 | 23 | 1 | 16 | |
| GSE54993 | XKR4 | 114786 | 1 | 16 | 53 | |
| GSE54994 | XKR4 | 114786 | 28 | 0 | 25 | |
| GSE60625 | XKR4 | 114786 | 0 | 4 | 7 | |
| GSE74703 | XKR4 | 114786 | 12 | 2 | 22 | |
| GSE74704 | XKR4 | 114786 | 10 | 0 | 10 | |
| TCGA | XKR4 | 114786 | 43 | 8 | 45 |
Total number of gains: 178; Total number of losses: 39; Total Number of normals: 271.
Somatic mutations of XKR4:
Generating mutation plots.
Highly correlated genes for XKR4:
Showing top 20/1143 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XKR4 | SORCS1 | 0.918393 | 4 | 0 | 4 |
| XKR4 | UBXN10 | 0.898377 | 3 | 0 | 3 |
| XKR4 | LDB3 | 0.891908 | 4 | 0 | 4 |
| XKR4 | RASD2 | 0.880587 | 3 | 0 | 3 |
| XKR4 | RBPMS2 | 0.875267 | 5 | 0 | 5 |
| XKR4 | MYOC | 0.872247 | 5 | 0 | 5 |
| XKR4 | PPP1R12B | 0.869867 | 5 | 0 | 5 |
| XKR4 | CYP21A2 | 0.866525 | 3 | 0 | 3 |
| XKR4 | RAB9B | 0.860813 | 5 | 0 | 5 |
| XKR4 | PGM5 | 0.859541 | 5 | 0 | 5 |
| XKR4 | SGCA | 0.859387 | 5 | 0 | 5 |
| XKR4 | HABP4 | 0.852978 | 3 | 0 | 3 |
| XKR4 | AOC3 | 0.852437 | 5 | 0 | 5 |
| XKR4 | ANO5 | 0.851815 | 5 | 0 | 5 |
| XKR4 | CACNB2 | 0.851051 | 5 | 0 | 5 |
| XKR4 | TNS1 | 0.849695 | 5 | 0 | 5 |
| XKR4 | PARD3B | 0.849367 | 4 | 0 | 4 |
| XKR4 | MAMDC2 | 0.848847 | 5 | 0 | 5 |
| XKR4 | HPSE2 | 0.845787 | 5 | 0 | 5 |
| XKR4 | ABCA6 | 0.84495 | 5 | 0 | 5 |
For details and further investigation, click here
