| Full name: syntrophin beta 1 | Alias Symbol: 59-DAP|A1B|BSYN2|TIP-43|SNT2 | ||
| Type: protein-coding gene | Cytoband: 8q24.12 | ||
| Entrez ID: 6641 | HGNC ID: HGNC:11168 | Ensembl Gene: ENSG00000172164 | OMIM ID: 600026 |
| Drug and gene relationship at DGIdb | |||
Expression of SNTB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNTB1 | 6641 | 226438_at | -0.9486 | 0.3287 | |
| GSE20347 | SNTB1 | 6641 | 208608_s_at | -0.0994 | 0.2225 | |
| GSE23400 | SNTB1 | 6641 | 208608_s_at | -0.1580 | 0.0012 | |
| GSE26886 | SNTB1 | 6641 | 226438_at | -1.0033 | 0.0124 | |
| GSE29001 | SNTB1 | 6641 | 208608_s_at | -0.0034 | 0.9853 | |
| GSE38129 | SNTB1 | 6641 | 214708_at | -0.4171 | 0.0000 | |
| GSE45670 | SNTB1 | 6641 | 226438_at | -1.2545 | 0.0000 | |
| GSE53622 | SNTB1 | 6641 | 16669 | -1.0025 | 0.0000 | |
| GSE53624 | SNTB1 | 6641 | 16669 | -0.7964 | 0.0000 | |
| GSE63941 | SNTB1 | 6641 | 226438_at | -0.5308 | 0.5293 | |
| GSE77861 | SNTB1 | 6641 | 226438_at | -0.0554 | 0.8436 | |
| GSE97050 | SNTB1 | 6641 | A_23_P95029 | -1.4009 | 0.0781 | |
| SRP007169 | SNTB1 | 6641 | RNAseq | -0.2604 | 0.6862 | |
| SRP064894 | SNTB1 | 6641 | RNAseq | -0.4222 | 0.1118 | |
| SRP133303 | SNTB1 | 6641 | RNAseq | -0.7417 | 0.0103 | |
| SRP159526 | SNTB1 | 6641 | RNAseq | -0.8809 | 0.0019 | |
| SRP193095 | SNTB1 | 6641 | RNAseq | -0.3506 | 0.1804 | |
| SRP219564 | SNTB1 | 6641 | RNAseq | -0.6340 | 0.4257 | |
| TCGA | SNTB1 | 6641 | RNAseq | -0.9250 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SNTB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNTB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNTB1 | 6641 | 19 | 1 | 10 | |
| GSE20123 | SNTB1 | 6641 | 20 | 1 | 9 | |
| GSE43470 | SNTB1 | 6641 | 23 | 0 | 20 | |
| GSE46452 | SNTB1 | 6641 | 27 | 0 | 32 | |
| GSE47630 | SNTB1 | 6641 | 24 | 0 | 16 | |
| GSE54993 | SNTB1 | 6641 | 0 | 20 | 50 | |
| GSE54994 | SNTB1 | 6641 | 38 | 0 | 15 | |
| GSE60625 | SNTB1 | 6641 | 0 | 4 | 7 | |
| GSE74703 | SNTB1 | 6641 | 19 | 0 | 17 | |
| GSE74704 | SNTB1 | 6641 | 13 | 1 | 6 | |
| TCGA | SNTB1 | 6641 | 66 | 3 | 27 |
Total number of gains: 249; Total number of losses: 30; Total Number of normals: 209.
Somatic mutations of SNTB1:
Generating mutation plots.
Highly correlated genes for SNTB1:
Showing top 20/963 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNTB1 | PDCD4 | 0.811339 | 3 | 0 | 3 |
| SNTB1 | FIBIN | 0.80626 | 3 | 0 | 3 |
| SNTB1 | MYOCD | 0.79798 | 4 | 0 | 4 |
| SNTB1 | KIAA0753 | 0.792875 | 3 | 0 | 3 |
| SNTB1 | GNB4 | 0.765315 | 3 | 0 | 3 |
| SNTB1 | RBM24 | 0.764678 | 4 | 0 | 4 |
| SNTB1 | C1QTNF7 | 0.763424 | 5 | 0 | 5 |
| SNTB1 | SLMAP | 0.756166 | 5 | 0 | 4 |
| SNTB1 | ANO5 | 0.755611 | 5 | 0 | 5 |
| SNTB1 | NEGR1 | 0.75324 | 5 | 0 | 5 |
| SNTB1 | MAP1LC3A | 0.751406 | 3 | 0 | 3 |
| SNTB1 | STARD9 | 0.744961 | 5 | 0 | 5 |
| SNTB1 | SORCS1 | 0.740681 | 4 | 0 | 4 |
| SNTB1 | RAB9B | 0.740568 | 5 | 0 | 5 |
| SNTB1 | CACNA1C | 0.735847 | 5 | 0 | 4 |
| SNTB1 | ANGPTL1 | 0.735365 | 5 | 0 | 4 |
| SNTB1 | CYS1 | 0.729488 | 5 | 0 | 4 |
| SNTB1 | MTURN | 0.727556 | 4 | 0 | 4 |
| SNTB1 | DUSP3 | 0.726158 | 6 | 0 | 5 |
| SNTB1 | DMPK | 0.722419 | 5 | 0 | 4 |
For details and further investigation, click here
