| Full name: F-box protein 8 | Alias Symbol: FBX8|FBS | ||
| Type: protein-coding gene | Cytoband: 4q34.1 | ||
| Entrez ID: 26269 | HGNC ID: HGNC:13587 | Ensembl Gene: ENSG00000164117 | OMIM ID: 605649 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO8 | 26269 | 1554806_a_at | -0.9786 | 0.0393 | |
| GSE26886 | FBXO8 | 26269 | 223240_at | -1.0629 | 0.0000 | |
| GSE45670 | FBXO8 | 26269 | 223240_at | -0.5126 | 0.0143 | |
| GSE53622 | FBXO8 | 26269 | 11028 | -0.6149 | 0.0000 | |
| GSE53624 | FBXO8 | 26269 | 11028 | -0.8690 | 0.0000 | |
| GSE63941 | FBXO8 | 26269 | 1554806_a_at | -0.0828 | 0.7986 | |
| GSE77861 | FBXO8 | 26269 | 1554806_a_at | -0.7952 | 0.0846 | |
| GSE97050 | FBXO8 | 26269 | A_23_P136012 | -0.2044 | 0.3684 | |
| SRP007169 | FBXO8 | 26269 | RNAseq | -1.0946 | 0.0026 | |
| SRP008496 | FBXO8 | 26269 | RNAseq | -1.0381 | 0.0000 | |
| SRP064894 | FBXO8 | 26269 | RNAseq | -0.7677 | 0.0000 | |
| SRP133303 | FBXO8 | 26269 | RNAseq | -0.1398 | 0.5468 | |
| SRP159526 | FBXO8 | 26269 | RNAseq | -0.7767 | 0.0057 | |
| SRP193095 | FBXO8 | 26269 | RNAseq | -0.9153 | 0.0000 | |
| SRP219564 | FBXO8 | 26269 | RNAseq | -0.8820 | 0.0016 | |
| TCGA | FBXO8 | 26269 | RNAseq | -0.1234 | 0.0275 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by FBXO8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO8 | 26269 | 1 | 10 | 19 | |
| GSE20123 | FBXO8 | 26269 | 1 | 10 | 19 | |
| GSE43470 | FBXO8 | 26269 | 0 | 13 | 30 | |
| GSE46452 | FBXO8 | 26269 | 1 | 36 | 22 | |
| GSE47630 | FBXO8 | 26269 | 0 | 22 | 18 | |
| GSE54993 | FBXO8 | 26269 | 10 | 0 | 60 | |
| GSE54994 | FBXO8 | 26269 | 2 | 12 | 39 | |
| GSE60625 | FBXO8 | 26269 | 0 | 0 | 11 | |
| GSE74703 | FBXO8 | 26269 | 0 | 11 | 25 | |
| GSE74704 | FBXO8 | 26269 | 0 | 5 | 15 | |
| TCGA | FBXO8 | 26269 | 11 | 37 | 48 |
Total number of gains: 26; Total number of losses: 156; Total Number of normals: 306.
Somatic mutations of FBXO8:
Generating mutation plots.
Highly correlated genes for FBXO8:
Showing top 20/1731 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO8 | EMCN | 0.816348 | 3 | 0 | 3 |
| FBXO8 | HBP1 | 0.815054 | 5 | 0 | 5 |
| FBXO8 | GGA3 | 0.813037 | 3 | 0 | 3 |
| FBXO8 | AK3 | 0.80731 | 7 | 0 | 7 |
| FBXO8 | COX15 | 0.800244 | 3 | 0 | 3 |
| FBXO8 | MSRA | 0.782309 | 6 | 0 | 6 |
| FBXO8 | FYTTD1 | 0.780249 | 4 | 0 | 4 |
| FBXO8 | SYTL4 | 0.779208 | 3 | 0 | 3 |
| FBXO8 | CETN2 | 0.774821 | 3 | 0 | 3 |
| FBXO8 | FCER1A | 0.771736 | 6 | 0 | 6 |
| FBXO8 | BRK1 | 0.768415 | 7 | 0 | 7 |
| FBXO8 | GALNT11 | 0.767188 | 3 | 0 | 3 |
| FBXO8 | GPD1L | 0.762531 | 7 | 0 | 7 |
| FBXO8 | KDM3A | 0.76026 | 3 | 0 | 3 |
| FBXO8 | WBP2 | 0.757396 | 3 | 0 | 3 |
| FBXO8 | PPP1R2 | 0.756581 | 3 | 0 | 3 |
| FBXO8 | HPGD | 0.756424 | 7 | 0 | 7 |
| FBXO8 | UFSP2 | 0.754583 | 8 | 0 | 7 |
| FBXO8 | ROR1 | 0.754263 | 5 | 0 | 5 |
| FBXO8 | SCP2 | 0.753682 | 7 | 0 | 6 |
For details and further investigation, click here
