Full name: CWC27 spliceosome associated cyclophilin | Alias Symbol: NY-CO-10|SDCCAG-10 | ||
Type: protein-coding gene | Cytoband: 5q12.3 | ||
Entrez ID: 10283 | HGNC ID: HGNC:10664 | Ensembl Gene: ENSG00000153015 | OMIM ID: 617170 |
Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CWC27:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE17351 | CWC27 | 10283 | 1555495_a_at | -0.1904 | 0.8421 | |
GSE26886 | CWC27 | 10283 | 1555495_a_at | 0.7356 | 0.0026 | |
GSE45670 | CWC27 | 10283 | 1555495_a_at | -0.0541 | 0.7401 | |
GSE53622 | CWC27 | 10283 | 71195 | -0.2434 | 0.0004 | |
GSE53624 | CWC27 | 10283 | 71195 | 0.0222 | 0.7968 | |
GSE63941 | CWC27 | 10283 | 1555495_a_at | -1.0370 | 0.0277 | |
GSE77861 | CWC27 | 10283 | 1555495_a_at | -0.1835 | 0.2769 | |
GSE97050 | CWC27 | 10283 | A_23_P92629 | -0.5068 | 0.1726 | |
SRP007169 | CWC27 | 10283 | RNAseq | 0.2797 | 0.4846 | |
SRP008496 | CWC27 | 10283 | RNAseq | 0.1704 | 0.5606 | |
SRP064894 | CWC27 | 10283 | RNAseq | -0.0413 | 0.7611 | |
SRP133303 | CWC27 | 10283 | RNAseq | -0.0492 | 0.6942 | |
SRP159526 | CWC27 | 10283 | RNAseq | 0.1441 | 0.6960 | |
SRP193095 | CWC27 | 10283 | RNAseq | -0.0261 | 0.8509 | |
SRP219564 | CWC27 | 10283 | RNAseq | -0.3923 | 0.2890 | |
TCGA | CWC27 | 10283 | RNAseq | -0.0601 | 0.2909 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CWC27 expression:
Note: Click image to view full size file.
Copy number change of CWC27:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | CWC27 | 10283 | 0 | 14 | 16 | |
GSE20123 | CWC27 | 10283 | 0 | 14 | 16 | |
GSE43470 | CWC27 | 10283 | 1 | 13 | 29 | |
GSE46452 | CWC27 | 10283 | 0 | 28 | 31 | |
GSE47630 | CWC27 | 10283 | 2 | 17 | 21 | |
GSE54993 | CWC27 | 10283 | 8 | 1 | 61 | |
GSE54994 | CWC27 | 10283 | 1 | 19 | 33 | |
GSE60625 | CWC27 | 10283 | 0 | 0 | 11 | |
GSE74703 | CWC27 | 10283 | 1 | 9 | 26 | |
GSE74704 | CWC27 | 10283 | 0 | 7 | 13 | |
TCGA | CWC27 | 10283 | 4 | 50 | 42 |
Total number of gains: 17; Total number of losses: 172; Total Number of normals: 299.
Somatic mutations of CWC27:
Generating mutation plots.
Highly correlated genes for CWC27:
Showing top 20/203 corelated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
CWC27 | MZT2B | 0.80543 | 3 | 0 | 3 |
CWC27 | RYBP | 0.799548 | 3 | 0 | 3 |
CWC27 | DDX59 | 0.779925 | 3 | 0 | 3 |
CWC27 | SLC25A29 | 0.778232 | 3 | 0 | 3 |
CWC27 | SSB | 0.750758 | 3 | 0 | 3 |
CWC27 | SEC22A | 0.750239 | 3 | 0 | 3 |
CWC27 | NAA15 | 0.748728 | 3 | 0 | 3 |
CWC27 | UBE2V2 | 0.748091 | 3 | 0 | 3 |
CWC27 | RPL14 | 0.744317 | 3 | 0 | 3 |
CWC27 | SLC35E1 | 0.735546 | 3 | 0 | 3 |
CWC27 | DNALI1 | 0.734661 | 3 | 0 | 3 |
CWC27 | FAM204A | 0.729513 | 5 | 0 | 5 |
CWC27 | PPIG | 0.729366 | 4 | 0 | 3 |
CWC27 | TOMM40L | 0.728091 | 3 | 0 | 3 |
CWC27 | PDHX | 0.725871 | 3 | 0 | 3 |
CWC27 | EDF1 | 0.720645 | 3 | 0 | 3 |
CWC27 | MAPK1IP1L | 0.720299 | 3 | 0 | 3 |
CWC27 | PET117 | 0.720158 | 3 | 0 | 3 |
CWC27 | PNMA1 | 0.716412 | 4 | 0 | 4 |
CWC27 | SRSF1 | 0.712578 | 3 | 0 | 3 |
For details and further investigation, click here