| Full name: RING1 and YY1 binding protein | Alias Symbol: YEAF1|AAP1|DEDAF | ||
| Type: protein-coding gene | Cytoband: 3p13 | ||
| Entrez ID: 23429 | HGNC ID: HGNC:10480 | Ensembl Gene: ENSG00000163602 | OMIM ID: 607535 |
| Drug and gene relationship at DGIdb | |||
Expression of RYBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RYBP | 23429 | 201845_s_at | -0.1057 | 0.6928 | |
| GSE20347 | RYBP | 23429 | 201844_s_at | -0.3541 | 0.0196 | |
| GSE23400 | RYBP | 23429 | 201846_s_at | -0.2146 | 0.0034 | |
| GSE26886 | RYBP | 23429 | 201845_s_at | -0.0736 | 0.7329 | |
| GSE29001 | RYBP | 23429 | 201844_s_at | -0.4007 | 0.2881 | |
| GSE38129 | RYBP | 23429 | 201844_s_at | -0.4809 | 0.0017 | |
| GSE45670 | RYBP | 23429 | 201845_s_at | -0.2706 | 0.0521 | |
| GSE63941 | RYBP | 23429 | 201845_s_at | -1.2795 | 0.0328 | |
| GSE77861 | RYBP | 23429 | 201846_s_at | 0.3532 | 0.3084 | |
| GSE97050 | RYBP | 23429 | A_23_P29365 | -0.5823 | 0.0828 | |
| SRP007169 | RYBP | 23429 | RNAseq | -0.9752 | 0.0031 | |
| SRP008496 | RYBP | 23429 | RNAseq | -0.4252 | 0.1264 | |
| SRP064894 | RYBP | 23429 | RNAseq | -0.5527 | 0.0018 | |
| SRP133303 | RYBP | 23429 | RNAseq | -0.0478 | 0.7391 | |
| SRP159526 | RYBP | 23429 | RNAseq | -0.3673 | 0.0726 | |
| SRP193095 | RYBP | 23429 | RNAseq | -0.4218 | 0.0000 | |
| SRP219564 | RYBP | 23429 | RNAseq | -0.6935 | 0.0019 | |
| TCGA | RYBP | 23429 | RNAseq | -0.1665 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RYBP expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RYBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RYBP | 23429 | 1 | 20 | 9 | |
| GSE20123 | RYBP | 23429 | 1 | 20 | 9 | |
| GSE43470 | RYBP | 23429 | 0 | 21 | 22 | |
| GSE46452 | RYBP | 23429 | 2 | 17 | 40 | |
| GSE47630 | RYBP | 23429 | 1 | 23 | 16 | |
| GSE54993 | RYBP | 23429 | 4 | 3 | 63 | |
| GSE54994 | RYBP | 23429 | 1 | 31 | 21 | |
| GSE60625 | RYBP | 23429 | 3 | 1 | 7 | |
| GSE74703 | RYBP | 23429 | 0 | 17 | 19 | |
| GSE74704 | RYBP | 23429 | 1 | 13 | 6 | |
| TCGA | RYBP | 23429 | 1 | 79 | 16 |
Total number of gains: 15; Total number of losses: 245; Total Number of normals: 228.
Somatic mutations of RYBP:
Generating mutation plots.
Highly correlated genes for RYBP:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RYBP | CWC27 | 0.799548 | 3 | 0 | 3 |
| RYBP | MED29 | 0.772091 | 3 | 0 | 3 |
| RYBP | CDADC1 | 0.756404 | 3 | 0 | 3 |
| RYBP | ZFYVE1 | 0.752831 | 3 | 0 | 3 |
| RYBP | ZNF397 | 0.735158 | 3 | 0 | 3 |
| RYBP | BRD2 | 0.723496 | 3 | 0 | 3 |
| RYBP | MPHOSPH8 | 0.715894 | 4 | 0 | 3 |
| RYBP | RBM41 | 0.713371 | 3 | 0 | 3 |
| RYBP | NEK7 | 0.706689 | 4 | 0 | 4 |
| RYBP | TRIM23 | 0.70173 | 5 | 0 | 4 |
| RYBP | RBFOX2 | 0.701272 | 3 | 0 | 3 |
| RYBP | PNPLA8 | 0.70102 | 3 | 0 | 3 |
| RYBP | STK38L | 0.698995 | 3 | 0 | 3 |
| RYBP | KIF5B | 0.692772 | 4 | 0 | 4 |
| RYBP | FASTKD2 | 0.692608 | 3 | 0 | 3 |
| RYBP | ANG | 0.692003 | 3 | 0 | 3 |
| RYBP | EXOC6 | 0.690215 | 3 | 0 | 3 |
| RYBP | NBEAL1 | 0.687619 | 3 | 0 | 3 |
| RYBP | CHUK | 0.687289 | 3 | 0 | 3 |
| RYBP | SNX13 | 0.683924 | 4 | 0 | 3 |
For details and further investigation, click here
