| Full name: PNMA family member 1 | Alias Symbol: MA1 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 9240 | HGNC ID: HGNC:9158 | Ensembl Gene: ENSG00000176903 | OMIM ID: 604010 |
| Drug and gene relationship at DGIdb | |||
Expression of PNMA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNMA1 | 9240 | 218224_at | -0.1435 | 0.8880 | |
| GSE20347 | PNMA1 | 9240 | 218224_at | 0.5840 | 0.0247 | |
| GSE23400 | PNMA1 | 9240 | 218224_at | 0.3264 | 0.0487 | |
| GSE26886 | PNMA1 | 9240 | 218224_at | 0.6032 | 0.0368 | |
| GSE29001 | PNMA1 | 9240 | 218224_at | 0.8058 | 0.0397 | |
| GSE38129 | PNMA1 | 9240 | 218224_at | 0.1389 | 0.6571 | |
| GSE45670 | PNMA1 | 9240 | 218224_at | -0.3094 | 0.3863 | |
| GSE53622 | PNMA1 | 9240 | 51921 | 0.0622 | 0.6448 | |
| GSE53624 | PNMA1 | 9240 | 51921 | 0.1799 | 0.0144 | |
| GSE63941 | PNMA1 | 9240 | 218224_at | -1.0042 | 0.1032 | |
| GSE77861 | PNMA1 | 9240 | 218224_at | 0.8565 | 0.2623 | |
| GSE97050 | PNMA1 | 9240 | A_23_P99771 | -0.3486 | 0.5552 | |
| SRP007169 | PNMA1 | 9240 | RNAseq | 0.5073 | 0.3307 | |
| SRP008496 | PNMA1 | 9240 | RNAseq | 1.0895 | 0.0052 | |
| SRP064894 | PNMA1 | 9240 | RNAseq | 0.3146 | 0.0082 | |
| SRP133303 | PNMA1 | 9240 | RNAseq | 0.2619 | 0.2834 | |
| SRP159526 | PNMA1 | 9240 | RNAseq | 0.2473 | 0.4990 | |
| SRP193095 | PNMA1 | 9240 | RNAseq | 0.5085 | 0.0164 | |
| SRP219564 | PNMA1 | 9240 | RNAseq | -0.2676 | 0.6935 | |
| TCGA | PNMA1 | 9240 | RNAseq | -0.1133 | 0.1157 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PNMA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNMA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNMA1 | 9240 | 8 | 2 | 20 | |
| GSE20123 | PNMA1 | 9240 | 8 | 2 | 20 | |
| GSE43470 | PNMA1 | 9240 | 8 | 3 | 32 | |
| GSE46452 | PNMA1 | 9240 | 16 | 3 | 40 | |
| GSE47630 | PNMA1 | 9240 | 11 | 8 | 21 | |
| GSE54993 | PNMA1 | 9240 | 3 | 8 | 59 | |
| GSE54994 | PNMA1 | 9240 | 18 | 4 | 31 | |
| GSE60625 | PNMA1 | 9240 | 0 | 2 | 9 | |
| GSE74703 | PNMA1 | 9240 | 7 | 3 | 26 | |
| GSE74704 | PNMA1 | 9240 | 3 | 2 | 15 | |
| TCGA | PNMA1 | 9240 | 31 | 16 | 49 |
Total number of gains: 113; Total number of losses: 53; Total Number of normals: 322.
Somatic mutations of PNMA1:
Generating mutation plots.
Highly correlated genes for PNMA1:
Showing top 20/715 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNMA1 | DMAP1 | 0.773463 | 3 | 0 | 3 |
| PNMA1 | GNPAT | 0.728564 | 3 | 0 | 3 |
| PNMA1 | ZNF609 | 0.71837 | 3 | 0 | 3 |
| PNMA1 | CWC27 | 0.716412 | 4 | 0 | 4 |
| PNMA1 | CWC22 | 0.711716 | 3 | 0 | 3 |
| PNMA1 | PSIP1 | 0.710368 | 3 | 0 | 3 |
| PNMA1 | UAP1 | 0.695456 | 3 | 0 | 3 |
| PNMA1 | LIN7B | 0.687005 | 3 | 0 | 3 |
| PNMA1 | CHMP1B | 0.6864 | 3 | 0 | 3 |
| PNMA1 | SMOX | 0.684701 | 3 | 0 | 3 |
| PNMA1 | TCEA2 | 0.683418 | 5 | 0 | 5 |
| PNMA1 | C11orf96 | 0.68231 | 3 | 0 | 3 |
| PNMA1 | MYO9B | 0.678233 | 3 | 0 | 3 |
| PNMA1 | U2SURP | 0.675726 | 3 | 0 | 3 |
| PNMA1 | ANG | 0.674465 | 5 | 0 | 4 |
| PNMA1 | KIF2A | 0.672433 | 3 | 0 | 3 |
| PNMA1 | DNAAF2 | 0.671542 | 4 | 0 | 4 |
| PNMA1 | PTPN21 | 0.669444 | 4 | 0 | 3 |
| PNMA1 | CRIM1 | 0.664745 | 4 | 0 | 4 |
| PNMA1 | TTC7B | 0.660558 | 8 | 0 | 7 |
For details and further investigation, click here
