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Multi-Omics Database of ESCC

 

DNALI1

 

Full name: dynein axonemal light intermediate chain 1 Alias Symbol: P28|hp28|dJ423B22.5
Type: protein-coding gene Cytoband: 1p34.3
Entrez ID: 7802 HGNC ID: HGNC:14353 Ensembl Gene: ENSG00000163879 OMIM ID: 602135
Drug and gene relationship at DGIdb

 

Expression of DNALI1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DNALI1 7802 227081_at -1.2818 0.2394
GSE20347 DNALI1 7802 205186_at -0.1462 0.0232
GSE23400 DNALI1 7802 205186_at -0.2072 0.0000
GSE26886 DNALI1 7802 205186_at 0.1068 0.5684
GSE29001 DNALI1 7802 205186_at 0.0011 0.9940
GSE38129 DNALI1 7802 205186_at -0.3388 0.0564
GSE45670 DNALI1 7802 205186_at -0.3234 0.0468
GSE53622 DNALI1 7802 39967 -0.4175 0.0001
GSE53624 DNALI1 7802 10501 -0.4008 0.0002
GSE63941 DNALI1 7802 205186_at -1.4675 0.0003
GSE77861 DNALI1 7802 205186_at -0.0883 0.3983
GSE97050 DNALI1 7802 A_33_P3289227 -0.1846 0.4854
SRP064894 DNALI1 7802 RNAseq -0.2210 0.5926
SRP133303 DNALI1 7802 RNAseq -0.4464 0.1826
SRP159526 DNALI1 7802 RNAseq -0.8305 0.1322
SRP193095 DNALI1 7802 RNAseq -0.0550 0.8664
SRP219564 DNALI1 7802 RNAseq -0.6182 0.4796
TCGA DNALI1 7802 RNAseq -1.5896 0.0000

Upregulated datasets: 0; Downregulated datasets: 2.  


 

Survival by DNALI1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of DNALI1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DNALI1 7802 2 4 24
GSE20123 DNALI1 7802 2 3 25
GSE43470 DNALI1 7802 7 3 33
GSE46452 DNALI1 7802 4 1 54
GSE47630 DNALI1 7802 8 3 29
GSE54993 DNALI1 7802 1 1 68
GSE54994 DNALI1 7802 11 2 40
GSE60625 DNALI1 7802 0 0 11
GSE74703 DNALI1 7802 6 2 28
GSE74704 DNALI1 7802 1 0 19
TCGA DNALI1 7802 12 16 68

Total number of gains: 54; Total number of losses: 35; Total Number of normals: 399.  


 

Somatic mutations of DNALI1:

 

Generating mutation plots.

 

Highly correlated genes for DNALI1:

 

Showing top 20/847 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DNALI1SYNC0.813815505
DNALI1TCEAL60.784733303
DNALI1PRICKLE20.783879505
DNALI1FNIP20.771492303
DNALI1NEK10.760588303
DNALI1MAN2B20.759192303
DNALI1PTPN210.753146303
DNALI1MAP40.75189505
DNALI1TNFAIP60.747892303
DNALI1RGMB0.74593504
DNALI1NFASC0.744107606
DNALI1ZNF3470.74106303
DNALI1FOXN30.740077404
DNALI1FKBP70.738006303
DNALI1CNST0.736277303
DNALI1CWC270.734661303
DNALI1MIER10.732724303
DNALI1ST6GALNAC60.732609404
DNALI1DCHS10.72877605
DNALI1TNFSF120.72874303

For details and further investigation, click here