| Full name: cytochrome b5 type A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18q22.3 | ||
| Entrez ID: 1528 | HGNC ID: HGNC:2570 | Ensembl Gene: ENSG00000166347 | OMIM ID: 613218 |
| Drug and gene relationship at DGIdb | |||
Expression of CYB5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYB5A | 1528 | 209366_x_at | -0.2384 | 0.6325 | |
| GSE20347 | CYB5A | 1528 | 209366_x_at | -0.4062 | 0.0639 | |
| GSE23400 | CYB5A | 1528 | 209366_x_at | -0.2288 | 0.0279 | |
| GSE26886 | CYB5A | 1528 | 209366_x_at | -0.5565 | 0.0212 | |
| GSE29001 | CYB5A | 1528 | 209366_x_at | -0.4370 | 0.2573 | |
| GSE38129 | CYB5A | 1528 | 209366_x_at | -0.2234 | 0.2112 | |
| GSE45670 | CYB5A | 1528 | 209366_x_at | -0.1641 | 0.5051 | |
| GSE53622 | CYB5A | 1528 | 127003 | -0.5099 | 0.0000 | |
| GSE53624 | CYB5A | 1528 | 127003 | -0.4669 | 0.0000 | |
| GSE63941 | CYB5A | 1528 | 209366_x_at | -1.8752 | 0.3071 | |
| GSE77861 | CYB5A | 1528 | 209366_x_at | -0.4480 | 0.5247 | |
| GSE97050 | CYB5A | 1528 | A_23_P101208 | -0.0245 | 0.9544 | |
| SRP007169 | CYB5A | 1528 | RNAseq | -0.2808 | 0.5100 | |
| SRP008496 | CYB5A | 1528 | RNAseq | -0.5984 | 0.1612 | |
| SRP064894 | CYB5A | 1528 | RNAseq | -0.2208 | 0.2437 | |
| SRP133303 | CYB5A | 1528 | RNAseq | -0.3699 | 0.0784 | |
| SRP159526 | CYB5A | 1528 | RNAseq | 0.3743 | 0.4996 | |
| SRP193095 | CYB5A | 1528 | RNAseq | -0.7411 | 0.0000 | |
| SRP219564 | CYB5A | 1528 | RNAseq | -0.8008 | 0.0031 | |
| TCGA | CYB5A | 1528 | RNAseq | -0.4133 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CYB5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYB5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYB5A | 1528 | 0 | 11 | 19 | |
| GSE20123 | CYB5A | 1528 | 0 | 11 | 19 | |
| GSE43470 | CYB5A | 1528 | 0 | 6 | 37 | |
| GSE46452 | CYB5A | 1528 | 1 | 26 | 32 | |
| GSE47630 | CYB5A | 1528 | 5 | 21 | 14 | |
| GSE54993 | CYB5A | 1528 | 9 | 0 | 61 | |
| GSE54994 | CYB5A | 1528 | 1 | 18 | 34 | |
| GSE60625 | CYB5A | 1528 | 0 | 4 | 7 | |
| GSE74703 | CYB5A | 1528 | 0 | 6 | 30 | |
| GSE74704 | CYB5A | 1528 | 0 | 9 | 11 | |
| TCGA | CYB5A | 1528 | 7 | 46 | 43 |
Total number of gains: 23; Total number of losses: 158; Total Number of normals: 307.
Somatic mutations of CYB5A:
Generating mutation plots.
Highly correlated genes for CYB5A:
Showing top 20/315 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYB5A | CIAPIN1 | 0.749999 | 3 | 0 | 3 |
| CYB5A | ARL6IP4 | 0.748159 | 3 | 0 | 3 |
| CYB5A | SLC35D2 | 0.739703 | 3 | 0 | 3 |
| CYB5A | ATP6V1H | 0.727433 | 4 | 0 | 4 |
| CYB5A | AGK | 0.718433 | 3 | 0 | 3 |
| CYB5A | GALNT11 | 0.707065 | 4 | 0 | 3 |
| CYB5A | TXLNG | 0.697247 | 3 | 0 | 3 |
| CYB5A | YAP1 | 0.694802 | 3 | 0 | 3 |
| CYB5A | MTCH2 | 0.69337 | 4 | 0 | 3 |
| CYB5A | RPA2 | 0.690498 | 3 | 0 | 3 |
| CYB5A | COPS3 | 0.69008 | 3 | 0 | 3 |
| CYB5A | APOO | 0.680857 | 3 | 0 | 3 |
| CYB5A | CD99 | 0.677993 | 3 | 0 | 3 |
| CYB5A | PAPSS2 | 0.677836 | 3 | 0 | 3 |
| CYB5A | PLAA | 0.675229 | 5 | 0 | 5 |
| CYB5A | CYFIP1 | 0.669294 | 4 | 0 | 3 |
| CYB5A | B4GALT5 | 0.668091 | 5 | 0 | 4 |
| CYB5A | HDHD2 | 0.667861 | 4 | 0 | 3 |
| CYB5A | UXT | 0.66621 | 5 | 0 | 4 |
| CYB5A | IER3IP1 | 0.6571 | 4 | 0 | 3 |
For details and further investigation, click here
