| Full name: immediate early response 3 interacting protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 51124 | HGNC ID: HGNC:18550 | Ensembl Gene: ENSG00000134049 | OMIM ID: 609382 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of IER3IP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IER3IP1 | 51124 | 223071_at | -0.0150 | 0.9813 | |
| GSE20347 | IER3IP1 | 51124 | 211406_at | -0.1630 | 0.1021 | |
| GSE23400 | IER3IP1 | 51124 | 211406_at | -0.0777 | 0.1402 | |
| GSE26886 | IER3IP1 | 51124 | 223071_at | -0.6671 | 0.0006 | |
| GSE29001 | IER3IP1 | 51124 | 211406_at | -0.2465 | 0.4191 | |
| GSE38129 | IER3IP1 | 51124 | 211406_at | 0.0266 | 0.9094 | |
| GSE45670 | IER3IP1 | 51124 | 223071_at | 0.0667 | 0.7060 | |
| GSE63941 | IER3IP1 | 51124 | 223071_at | -0.3462 | 0.3871 | |
| GSE77861 | IER3IP1 | 51124 | 223071_at | 0.2563 | 0.5082 | |
| GSE97050 | IER3IP1 | 51124 | A_23_P4474 | 0.2959 | 0.2539 | |
| SRP007169 | IER3IP1 | 51124 | RNAseq | -0.6480 | 0.0991 | |
| SRP008496 | IER3IP1 | 51124 | RNAseq | 0.2048 | 0.5881 | |
| SRP064894 | IER3IP1 | 51124 | RNAseq | 0.2786 | 0.0535 | |
| SRP133303 | IER3IP1 | 51124 | RNAseq | 0.4232 | 0.0532 | |
| SRP159526 | IER3IP1 | 51124 | RNAseq | 0.3169 | 0.3709 | |
| SRP193095 | IER3IP1 | 51124 | RNAseq | -0.1748 | 0.2186 | |
| SRP219564 | IER3IP1 | 51124 | RNAseq | 0.0331 | 0.9242 | |
| TCGA | IER3IP1 | 51124 | RNAseq | 0.0483 | 0.4157 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IER3IP1 expression:
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| TCGA |
Note: Click image to view full size file.
Copy number change of IER3IP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IER3IP1 | 51124 | 1 | 8 | 21 | |
| GSE20123 | IER3IP1 | 51124 | 1 | 8 | 21 | |
| GSE43470 | IER3IP1 | 51124 | 0 | 5 | 38 | |
| GSE46452 | IER3IP1 | 51124 | 1 | 26 | 32 | |
| GSE47630 | IER3IP1 | 51124 | 5 | 20 | 15 | |
| GSE54993 | IER3IP1 | 51124 | 8 | 1 | 61 | |
| GSE54994 | IER3IP1 | 51124 | 2 | 15 | 36 | |
| GSE60625 | IER3IP1 | 51124 | 0 | 4 | 7 | |
| GSE74703 | IER3IP1 | 51124 | 0 | 4 | 32 | |
| GSE74704 | IER3IP1 | 51124 | 0 | 6 | 14 | |
| TCGA | IER3IP1 | 51124 | 15 | 39 | 42 |
Total number of gains: 33; Total number of losses: 136; Total Number of normals: 319.
Somatic mutations of IER3IP1:
Generating mutation plots.
Highly correlated genes for IER3IP1:
Showing top 20/452 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IER3IP1 | PRKCH | 0.8057 | 3 | 0 | 3 |
| IER3IP1 | SMC5 | 0.780656 | 3 | 0 | 3 |
| IER3IP1 | RTN4IP1 | 0.778054 | 3 | 0 | 3 |
| IER3IP1 | UBA3 | 0.772869 | 3 | 0 | 3 |
| IER3IP1 | DNAJB6 | 0.771612 | 3 | 0 | 3 |
| IER3IP1 | LCMT1 | 0.752925 | 3 | 0 | 3 |
| IER3IP1 | LPAR6 | 0.749221 | 3 | 0 | 3 |
| IER3IP1 | PLAA | 0.748498 | 4 | 0 | 4 |
| IER3IP1 | SMAP2 | 0.73747 | 3 | 0 | 3 |
| IER3IP1 | SLCO2B1 | 0.734617 | 3 | 0 | 3 |
| IER3IP1 | NAA20 | 0.731874 | 3 | 0 | 3 |
| IER3IP1 | CAPRIN1 | 0.731725 | 3 | 0 | 3 |
| IER3IP1 | SREBF2 | 0.729471 | 3 | 0 | 3 |
| IER3IP1 | MAD2L1BP | 0.726667 | 3 | 0 | 3 |
| IER3IP1 | PLD1 | 0.724468 | 3 | 0 | 3 |
| IER3IP1 | COPS5 | 0.724401 | 3 | 0 | 3 |
| IER3IP1 | HS6ST1 | 0.720141 | 3 | 0 | 3 |
| IER3IP1 | THAP2 | 0.716772 | 3 | 0 | 3 |
| IER3IP1 | MRPL46 | 0.71498 | 3 | 0 | 3 |
| IER3IP1 | DNAJC19 | 0.714727 | 3 | 0 | 3 |
For details and further investigation, click here
