| Full name: mitochondrial carrier 2 | Alias Symbol: SLC25A50 | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 23788 | HGNC ID: HGNC:17587 | Ensembl Gene: ENSG00000109919 | OMIM ID: 613221 |
Screen Evidence:
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Expression of MTCH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTCH2 | 23788 | 217772_s_at | 0.2885 | 0.4454 | |
| GSE20347 | MTCH2 | 23788 | 217772_s_at | -0.2110 | 0.4009 | |
| GSE23400 | MTCH2 | 23788 | 217772_s_at | 0.1918 | 0.0181 | |
| GSE26886 | MTCH2 | 23788 | 217772_s_at | -0.2375 | 0.2817 | |
| GSE29001 | MTCH2 | 23788 | 217772_s_at | -0.2909 | 0.4577 | |
| GSE38129 | MTCH2 | 23788 | 217772_s_at | 0.1632 | 0.4979 | |
| GSE45670 | MTCH2 | 23788 | 217772_s_at | 0.1776 | 0.2202 | |
| GSE63941 | MTCH2 | 23788 | 217772_s_at | 0.1276 | 0.8121 | |
| GSE77861 | MTCH2 | 23788 | 217772_s_at | 0.0205 | 0.9546 | |
| GSE97050 | MTCH2 | 23788 | A_24_P934563 | -0.0805 | 0.7316 | |
| SRP007169 | MTCH2 | 23788 | RNAseq | -0.8468 | 0.0124 | |
| SRP008496 | MTCH2 | 23788 | RNAseq | -0.3978 | 0.1841 | |
| SRP064894 | MTCH2 | 23788 | RNAseq | -0.0109 | 0.9386 | |
| SRP133303 | MTCH2 | 23788 | RNAseq | 0.0103 | 0.9330 | |
| SRP159526 | MTCH2 | 23788 | RNAseq | -0.1342 | 0.5637 | |
| SRP193095 | MTCH2 | 23788 | RNAseq | -0.6250 | 0.0000 | |
| SRP219564 | MTCH2 | 23788 | RNAseq | -0.2965 | 0.1723 | |
| TCGA | MTCH2 | 23788 | RNAseq | 0.1479 | 0.0027 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MTCH2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MTCH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTCH2 | 23788 | 3 | 7 | 20 | |
| GSE20123 | MTCH2 | 23788 | 3 | 6 | 21 | |
| GSE43470 | MTCH2 | 23788 | 1 | 4 | 38 | |
| GSE46452 | MTCH2 | 23788 | 8 | 5 | 46 | |
| GSE47630 | MTCH2 | 23788 | 3 | 9 | 28 | |
| GSE54993 | MTCH2 | 23788 | 3 | 0 | 67 | |
| GSE54994 | MTCH2 | 23788 | 1 | 11 | 41 | |
| GSE60625 | MTCH2 | 23788 | 0 | 0 | 11 | |
| GSE74703 | MTCH2 | 23788 | 1 | 2 | 33 | |
| GSE74704 | MTCH2 | 23788 | 2 | 4 | 14 | |
| TCGA | MTCH2 | 23788 | 10 | 20 | 66 |
Total number of gains: 35; Total number of losses: 68; Total Number of normals: 385.
Somatic mutations of MTCH2:
Generating mutation plots.
Highly correlated genes for MTCH2:
Showing top 20/545 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTCH2 | ZNF184 | 0.806957 | 3 | 0 | 3 |
| MTCH2 | UBP1 | 0.775294 | 3 | 0 | 3 |
| MTCH2 | POLDIP2 | 0.769793 | 4 | 0 | 4 |
| MTCH2 | FAM53B | 0.761494 | 3 | 0 | 3 |
| MTCH2 | UNC5CL | 0.751475 | 3 | 0 | 3 |
| MTCH2 | MDH1 | 0.745545 | 3 | 0 | 3 |
| MTCH2 | MEX3C | 0.742028 | 3 | 0 | 3 |
| MTCH2 | CDYL | 0.742007 | 4 | 0 | 3 |
| MTCH2 | MRRF | 0.740891 | 3 | 0 | 3 |
| MTCH2 | VPS26B | 0.733367 | 3 | 0 | 3 |
| MTCH2 | NF2 | 0.732546 | 3 | 0 | 3 |
| MTCH2 | ZKSCAN4 | 0.732036 | 3 | 0 | 3 |
| MTCH2 | MRPL30 | 0.731627 | 3 | 0 | 3 |
| MTCH2 | SSR1 | 0.727747 | 3 | 0 | 3 |
| MTCH2 | ALG2 | 0.7276 | 3 | 0 | 3 |
| MTCH2 | MAGED1 | 0.724357 | 3 | 0 | 3 |
| MTCH2 | RTF1 | 0.723806 | 3 | 0 | 3 |
| MTCH2 | ERP29 | 0.722809 | 3 | 0 | 3 |
| MTCH2 | HAVCR2 | 0.722293 | 3 | 0 | 3 |
| MTCH2 | MCCC2 | 0.721644 | 3 | 0 | 3 |
For details and further investigation, click here
