| Full name: acylglycerol kinase | Alias Symbol: FLJ10842 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 55750 | HGNC ID: HGNC:21869 | Ensembl Gene: ENSG00000006530 | OMIM ID: 610345 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of AGK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGK | 55750 | 222132_s_at | 0.0025 | 0.9968 | |
| GSE20347 | AGK | 55750 | 222132_s_at | 0.3978 | 0.0000 | |
| GSE23400 | AGK | 55750 | 222132_s_at | 0.3000 | 0.0000 | |
| GSE26886 | AGK | 55750 | 222132_s_at | -0.1160 | 0.5512 | |
| GSE29001 | AGK | 55750 | 222132_s_at | 0.3718 | 0.0244 | |
| GSE38129 | AGK | 55750 | 222132_s_at | 0.4523 | 0.0000 | |
| GSE45670 | AGK | 55750 | 222132_s_at | 0.1933 | 0.1845 | |
| GSE53622 | AGK | 55750 | 93571 | 0.1192 | 0.0783 | |
| GSE53624 | AGK | 55750 | 93571 | 0.2750 | 0.0003 | |
| GSE63941 | AGK | 55750 | 222132_s_at | 0.7220 | 0.0955 | |
| GSE77861 | AGK | 55750 | 222132_s_at | 0.4001 | 0.0228 | |
| GSE97050 | AGK | 55750 | A_23_P309224 | 0.2335 | 0.3918 | |
| SRP007169 | AGK | 55750 | RNAseq | 0.4996 | 0.2039 | |
| SRP008496 | AGK | 55750 | RNAseq | 0.7353 | 0.0077 | |
| SRP064894 | AGK | 55750 | RNAseq | 0.1954 | 0.3561 | |
| SRP133303 | AGK | 55750 | RNAseq | 0.2625 | 0.0831 | |
| SRP159526 | AGK | 55750 | RNAseq | 0.2222 | 0.2491 | |
| SRP193095 | AGK | 55750 | RNAseq | 0.0960 | 0.3704 | |
| SRP219564 | AGK | 55750 | RNAseq | -0.1099 | 0.6969 | |
| TCGA | AGK | 55750 | RNAseq | 0.0692 | 0.2014 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AGK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGK | 55750 | 5 | 2 | 23 | |
| GSE20123 | AGK | 55750 | 5 | 2 | 23 | |
| GSE43470 | AGK | 55750 | 2 | 4 | 37 | |
| GSE46452 | AGK | 55750 | 7 | 2 | 50 | |
| GSE47630 | AGK | 55750 | 6 | 7 | 27 | |
| GSE54993 | AGK | 55750 | 3 | 5 | 62 | |
| GSE54994 | AGK | 55750 | 5 | 8 | 40 | |
| GSE60625 | AGK | 55750 | 0 | 0 | 11 | |
| GSE74703 | AGK | 55750 | 2 | 4 | 30 | |
| GSE74704 | AGK | 55750 | 1 | 2 | 17 | |
| TCGA | AGK | 55750 | 29 | 23 | 44 |
Total number of gains: 65; Total number of losses: 59; Total Number of normals: 364.
Somatic mutations of AGK:
Generating mutation plots.
Highly correlated genes for AGK:
Showing top 20/838 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGK | GMCL1 | 0.790837 | 3 | 0 | 3 |
| AGK | GABRA3 | 0.784079 | 3 | 0 | 3 |
| AGK | RNF130 | 0.765243 | 3 | 0 | 3 |
| AGK | MRPL38 | 0.758426 | 4 | 0 | 4 |
| AGK | CDKN2D | 0.749324 | 3 | 0 | 3 |
| AGK | HAS3 | 0.738491 | 3 | 0 | 3 |
| AGK | FARS2 | 0.735033 | 3 | 0 | 3 |
| AGK | TBRG4 | 0.731368 | 4 | 0 | 3 |
| AGK | LRRC14 | 0.730496 | 3 | 0 | 3 |
| AGK | TRMU | 0.726191 | 3 | 0 | 3 |
| AGK | CYB5A | 0.718433 | 3 | 0 | 3 |
| AGK | DNMBP | 0.71647 | 3 | 0 | 3 |
| AGK | DNAJB11 | 0.7118 | 3 | 0 | 3 |
| AGK | EXOC4 | 0.710851 | 4 | 0 | 4 |
| AGK | CD2BP2 | 0.710463 | 3 | 0 | 3 |
| AGK | MRPL27 | 0.708553 | 3 | 0 | 3 |
| AGK | TUFM | 0.707656 | 4 | 0 | 3 |
| AGK | SNF8 | 0.700656 | 3 | 0 | 3 |
| AGK | UCP2 | 0.698546 | 4 | 0 | 3 |
| AGK | AMMECR1L | 0.695136 | 3 | 0 | 3 |
For details and further investigation, click here
