| Full name: derlin 2 | Alias Symbol: F-LAN-1|FLANa|F-LANa|CGI-101|derlin-2 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 51009 | HGNC ID: HGNC:17943 | Ensembl Gene: ENSG00000072849 | OMIM ID: 610304 |
| Drug and gene relationship at DGIdb | |||
Expression of DERL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DERL2 | 51009 | 218333_at | 0.1650 | 0.6261 | |
| GSE20347 | DERL2 | 51009 | 218333_at | 0.0206 | 0.8949 | |
| GSE23400 | DERL2 | 51009 | 218333_at | 0.3643 | 0.0000 | |
| GSE26886 | DERL2 | 51009 | 218333_at | 0.5238 | 0.0011 | |
| GSE29001 | DERL2 | 51009 | 218333_at | 0.1637 | 0.6514 | |
| GSE38129 | DERL2 | 51009 | 218333_at | 0.2533 | 0.0275 | |
| GSE45670 | DERL2 | 51009 | 218333_at | 0.3086 | 0.0218 | |
| GSE53622 | DERL2 | 51009 | 36560 | 0.2605 | 0.0002 | |
| GSE53624 | DERL2 | 51009 | 36560 | 0.2804 | 0.0001 | |
| GSE63941 | DERL2 | 51009 | 218333_at | -0.2776 | 0.3314 | |
| GSE77861 | DERL2 | 51009 | 218333_at | 0.2595 | 0.3509 | |
| GSE97050 | DERL2 | 51009 | A_23_P118749 | 0.6703 | 0.1057 | |
| SRP007169 | DERL2 | 51009 | RNAseq | -0.1821 | 0.6355 | |
| SRP008496 | DERL2 | 51009 | RNAseq | 0.0188 | 0.9280 | |
| SRP064894 | DERL2 | 51009 | RNAseq | 0.2116 | 0.2201 | |
| SRP133303 | DERL2 | 51009 | RNAseq | 0.2371 | 0.1927 | |
| SRP159526 | DERL2 | 51009 | RNAseq | 0.3112 | 0.0350 | |
| SRP193095 | DERL2 | 51009 | RNAseq | 0.0491 | 0.5748 | |
| SRP219564 | DERL2 | 51009 | RNAseq | 0.6365 | 0.1283 | |
| TCGA | DERL2 | 51009 | RNAseq | -0.0296 | 0.5928 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DERL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DERL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DERL2 | 51009 | 5 | 2 | 23 | |
| GSE20123 | DERL2 | 51009 | 5 | 3 | 22 | |
| GSE43470 | DERL2 | 51009 | 1 | 6 | 36 | |
| GSE46452 | DERL2 | 51009 | 34 | 1 | 24 | |
| GSE47630 | DERL2 | 51009 | 7 | 1 | 32 | |
| GSE54993 | DERL2 | 51009 | 4 | 3 | 63 | |
| GSE54994 | DERL2 | 51009 | 5 | 8 | 40 | |
| GSE60625 | DERL2 | 51009 | 4 | 0 | 7 | |
| GSE74703 | DERL2 | 51009 | 1 | 3 | 32 | |
| GSE74704 | DERL2 | 51009 | 3 | 1 | 16 | |
| TCGA | DERL2 | 51009 | 18 | 20 | 58 |
Total number of gains: 87; Total number of losses: 48; Total Number of normals: 353.
Somatic mutations of DERL2:
Generating mutation plots.
Highly correlated genes for DERL2:
Showing top 20/679 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DERL2 | TYW5 | 0.785946 | 3 | 0 | 3 |
| DERL2 | ZNF121 | 0.760612 | 3 | 0 | 3 |
| DERL2 | FIP1L1 | 0.753437 | 4 | 0 | 4 |
| DERL2 | GNS | 0.752481 | 3 | 0 | 3 |
| DERL2 | NUDT19 | 0.744743 | 3 | 0 | 3 |
| DERL2 | TMEM237 | 0.737647 | 4 | 0 | 3 |
| DERL2 | NUAK1 | 0.732729 | 3 | 0 | 3 |
| DERL2 | GNA13 | 0.731659 | 3 | 0 | 3 |
| DERL2 | UGGT2 | 0.727798 | 3 | 0 | 3 |
| DERL2 | TOMM5 | 0.720511 | 3 | 0 | 3 |
| DERL2 | RICTOR | 0.71722 | 3 | 0 | 3 |
| DERL2 | XXYLT1 | 0.715763 | 3 | 0 | 3 |
| DERL2 | AP3D1 | 0.714032 | 3 | 0 | 3 |
| DERL2 | SPCS2 | 0.711337 | 3 | 0 | 3 |
| DERL2 | RILPL2 | 0.708388 | 3 | 0 | 3 |
| DERL2 | RIMKLB | 0.707314 | 3 | 0 | 3 |
| DERL2 | CHCHD3 | 0.694438 | 3 | 0 | 3 |
| DERL2 | ZGPAT | 0.694364 | 3 | 0 | 3 |
| DERL2 | PSMG4 | 0.690719 | 3 | 0 | 3 |
| DERL2 | WDR81 | 0.689695 | 4 | 0 | 4 |
For details and further investigation, click here
