| Full name: adaptor related protein complex 3 subunit delta 1 | Alias Symbol: ADTD | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 8943 | HGNC ID: HGNC:568 | Ensembl Gene: ENSG00000065000 | OMIM ID: 607246 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of AP3D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AP3D1 | 8943 | 206592_s_at | 0.3221 | 0.2297 | |
| GSE20347 | AP3D1 | 8943 | 206592_s_at | -0.0007 | 0.9973 | |
| GSE23400 | AP3D1 | 8943 | 206592_s_at | 0.0809 | 0.1061 | |
| GSE26886 | AP3D1 | 8943 | 206592_s_at | 0.3182 | 0.0103 | |
| GSE29001 | AP3D1 | 8943 | 206592_s_at | -0.0733 | 0.7809 | |
| GSE38129 | AP3D1 | 8943 | 206592_s_at | 0.0901 | 0.3414 | |
| GSE45670 | AP3D1 | 8943 | 206592_s_at | 0.2522 | 0.0072 | |
| GSE53622 | AP3D1 | 8943 | 15293 | 0.0721 | 0.3721 | |
| GSE53624 | AP3D1 | 8943 | 15293 | 0.2626 | 0.0002 | |
| GSE63941 | AP3D1 | 8943 | 206592_s_at | -0.0520 | 0.8956 | |
| GSE77861 | AP3D1 | 8943 | 206592_s_at | 0.2600 | 0.1109 | |
| GSE97050 | AP3D1 | 8943 | A_33_P3571120 | 0.1001 | 0.8179 | |
| SRP007169 | AP3D1 | 8943 | RNAseq | 0.3422 | 0.3837 | |
| SRP008496 | AP3D1 | 8943 | RNAseq | 0.0826 | 0.7497 | |
| SRP064894 | AP3D1 | 8943 | RNAseq | 0.0511 | 0.7069 | |
| SRP133303 | AP3D1 | 8943 | RNAseq | 0.1400 | 0.4440 | |
| SRP159526 | AP3D1 | 8943 | RNAseq | 0.0364 | 0.8751 | |
| SRP193095 | AP3D1 | 8943 | RNAseq | 0.1647 | 0.1749 | |
| SRP219564 | AP3D1 | 8943 | RNAseq | 0.0230 | 0.9118 | |
| TCGA | AP3D1 | 8943 | RNAseq | -0.0457 | 0.2442 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AP3D1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AP3D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AP3D1 | 8943 | 4 | 6 | 20 | |
| GSE20123 | AP3D1 | 8943 | 4 | 5 | 21 | |
| GSE43470 | AP3D1 | 8943 | 1 | 10 | 32 | |
| GSE46452 | AP3D1 | 8943 | 47 | 1 | 11 | |
| GSE47630 | AP3D1 | 8943 | 5 | 7 | 28 | |
| GSE54993 | AP3D1 | 8943 | 16 | 3 | 51 | |
| GSE54994 | AP3D1 | 8943 | 8 | 15 | 30 | |
| GSE60625 | AP3D1 | 8943 | 9 | 0 | 2 | |
| GSE74703 | AP3D1 | 8943 | 1 | 7 | 28 | |
| GSE74704 | AP3D1 | 8943 | 3 | 3 | 14 | |
| TCGA | AP3D1 | 8943 | 6 | 25 | 65 |
Total number of gains: 104; Total number of losses: 82; Total Number of normals: 302.
Somatic mutations of AP3D1:
Generating mutation plots.
Highly correlated genes for AP3D1:
Showing top 20/708 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AP3D1 | PPHLN1 | 0.834074 | 3 | 0 | 3 |
| AP3D1 | TOPBP1 | 0.832226 | 3 | 0 | 3 |
| AP3D1 | NFE2L1 | 0.793501 | 3 | 0 | 3 |
| AP3D1 | UBQLN4 | 0.769544 | 3 | 0 | 3 |
| AP3D1 | LSM10 | 0.767297 | 3 | 0 | 3 |
| AP3D1 | DNTTIP1 | 0.763426 | 3 | 0 | 3 |
| AP3D1 | MRTO4 | 0.760586 | 3 | 0 | 3 |
| AP3D1 | CDC25A | 0.755474 | 3 | 0 | 3 |
| AP3D1 | FAF2 | 0.754739 | 4 | 0 | 4 |
| AP3D1 | C3orf33 | 0.746379 | 3 | 0 | 3 |
| AP3D1 | NACC1 | 0.74277 | 5 | 0 | 5 |
| AP3D1 | ZNF827 | 0.742333 | 4 | 0 | 4 |
| AP3D1 | INTS1 | 0.736631 | 5 | 0 | 5 |
| AP3D1 | DHX36 | 0.733255 | 3 | 0 | 3 |
| AP3D1 | ZNF496 | 0.732547 | 3 | 0 | 3 |
| AP3D1 | MSL2 | 0.732171 | 3 | 0 | 3 |
| AP3D1 | GLI3 | 0.728175 | 3 | 0 | 3 |
| AP3D1 | TRUB2 | 0.727604 | 3 | 0 | 3 |
| AP3D1 | DERL1 | 0.725158 | 4 | 0 | 4 |
| AP3D1 | KIF23 | 0.723067 | 3 | 0 | 3 |
For details and further investigation, click here
