| Full name: factor interacting with PAPOLA and CPSF1 | Alias Symbol: DKFZp586K0717|FIP1 | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 81608 | HGNC ID: HGNC:19124 | Ensembl Gene: ENSG00000145216 | OMIM ID: 607686 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FIP1L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FIP1L1 | 81608 | 221007_s_at | 0.1272 | 0.8033 | |
| GSE20347 | FIP1L1 | 81608 | 221007_s_at | 0.0566 | 0.5889 | |
| GSE23400 | FIP1L1 | 81608 | 221007_s_at | 0.1293 | 0.0068 | |
| GSE26886 | FIP1L1 | 81608 | 221007_s_at | 1.0097 | 0.0000 | |
| GSE29001 | FIP1L1 | 81608 | 221007_s_at | 0.4749 | 0.3015 | |
| GSE38129 | FIP1L1 | 81608 | 221007_s_at | 0.2988 | 0.2375 | |
| GSE45670 | FIP1L1 | 81608 | 221007_s_at | 0.1505 | 0.4855 | |
| GSE63941 | FIP1L1 | 81608 | 221007_s_at | -0.7573 | 0.1320 | |
| GSE77861 | FIP1L1 | 81608 | 221007_s_at | 0.0758 | 0.7542 | |
| GSE97050 | FIP1L1 | 81608 | A_23_P58337 | -0.0838 | 0.7232 | |
| SRP007169 | FIP1L1 | 81608 | RNAseq | 0.0491 | 0.9023 | |
| SRP008496 | FIP1L1 | 81608 | RNAseq | 0.3015 | 0.1974 | |
| SRP064894 | FIP1L1 | 81608 | RNAseq | 0.3796 | 0.0308 | |
| SRP133303 | FIP1L1 | 81608 | RNAseq | 0.1421 | 0.3555 | |
| SRP159526 | FIP1L1 | 81608 | RNAseq | 0.3310 | 0.1692 | |
| SRP193095 | FIP1L1 | 81608 | RNAseq | 0.0541 | 0.6472 | |
| SRP219564 | FIP1L1 | 81608 | RNAseq | 0.0792 | 0.7504 | |
| TCGA | FIP1L1 | 81608 | RNAseq | 0.1462 | 0.0067 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FIP1L1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FIP1L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FIP1L1 | 81608 | 3 | 11 | 16 | |
| GSE20123 | FIP1L1 | 81608 | 2 | 11 | 17 | |
| GSE43470 | FIP1L1 | 81608 | 0 | 14 | 29 | |
| GSE46452 | FIP1L1 | 81608 | 1 | 36 | 22 | |
| GSE47630 | FIP1L1 | 81608 | 1 | 18 | 21 | |
| GSE54993 | FIP1L1 | 81608 | 7 | 0 | 63 | |
| GSE54994 | FIP1L1 | 81608 | 2 | 10 | 41 | |
| GSE60625 | FIP1L1 | 81608 | 0 | 0 | 11 | |
| GSE74703 | FIP1L1 | 81608 | 0 | 12 | 24 | |
| GSE74704 | FIP1L1 | 81608 | 1 | 6 | 13 | |
| TCGA | FIP1L1 | 81608 | 21 | 26 | 49 |
Total number of gains: 38; Total number of losses: 144; Total Number of normals: 306.
Somatic mutations of FIP1L1:
Generating mutation plots.
Highly correlated genes for FIP1L1:
Showing top 20/455 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FIP1L1 | SLC25A29 | 0.869795 | 3 | 0 | 3 |
| FIP1L1 | ALKBH6 | 0.848561 | 3 | 0 | 3 |
| FIP1L1 | SURF6 | 0.833412 | 3 | 0 | 3 |
| FIP1L1 | KRTCAP2 | 0.824794 | 3 | 0 | 3 |
| FIP1L1 | DHX36 | 0.810926 | 3 | 0 | 3 |
| FIP1L1 | WDR81 | 0.800291 | 3 | 0 | 3 |
| FIP1L1 | ZNF584 | 0.796884 | 3 | 0 | 3 |
| FIP1L1 | LRP5L | 0.792169 | 3 | 0 | 3 |
| FIP1L1 | NAF1 | 0.792098 | 3 | 0 | 3 |
| FIP1L1 | ZNF251 | 0.789648 | 3 | 0 | 3 |
| FIP1L1 | UTP20 | 0.781924 | 3 | 0 | 3 |
| FIP1L1 | INTS8 | 0.776659 | 3 | 0 | 3 |
| FIP1L1 | KLHL24 | 0.77532 | 3 | 0 | 3 |
| FIP1L1 | SFSWAP | 0.772289 | 4 | 0 | 4 |
| FIP1L1 | CCAR1 | 0.77226 | 4 | 0 | 3 |
| FIP1L1 | ZFYVE27 | 0.768859 | 3 | 0 | 3 |
| FIP1L1 | SSBP4 | 0.765383 | 3 | 0 | 3 |
| FIP1L1 | MSTO1 | 0.765147 | 3 | 0 | 3 |
| FIP1L1 | RPL22L1 | 0.761229 | 3 | 0 | 3 |
| FIP1L1 | MRPL36 | 0.758735 | 3 | 0 | 3 |
For details and further investigation, click here
