| Full name: disco interacting protein 2 homolog A | Alias Symbol: Dip2|KIAA0184 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 23181 | HGNC ID: HGNC:17217 | Ensembl Gene: ENSG00000160305 | OMIM ID: 607711 |
| Drug and gene relationship at DGIdb | |||
Expression of DIP2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DIP2A | 23181 | 215529_x_at | 0.2764 | 0.6971 | |
| GSE20347 | DIP2A | 23181 | 215529_x_at | 0.4080 | 0.0230 | |
| GSE23400 | DIP2A | 23181 | 215529_x_at | 0.0768 | 0.2325 | |
| GSE26886 | DIP2A | 23181 | 215529_x_at | 0.0576 | 0.7632 | |
| GSE29001 | DIP2A | 23181 | 215529_x_at | 0.2218 | 0.2289 | |
| GSE38129 | DIP2A | 23181 | 215529_x_at | 0.1731 | 0.3702 | |
| GSE45670 | DIP2A | 23181 | 215529_x_at | 0.2738 | 0.0123 | |
| GSE53622 | DIP2A | 23181 | 68160 | -0.7742 | 0.0000 | |
| GSE53624 | DIP2A | 23181 | 68160 | -0.6884 | 0.0000 | |
| GSE63941 | DIP2A | 23181 | 215529_x_at | -0.1898 | 0.2489 | |
| GSE77861 | DIP2A | 23181 | 215529_x_at | 0.3596 | 0.2347 | |
| GSE97050 | DIP2A | 23181 | A_24_P7179 | -0.3685 | 0.1556 | |
| SRP007169 | DIP2A | 23181 | RNAseq | 0.0468 | 0.9109 | |
| SRP008496 | DIP2A | 23181 | RNAseq | 0.3990 | 0.1644 | |
| SRP064894 | DIP2A | 23181 | RNAseq | 0.0013 | 0.9954 | |
| SRP133303 | DIP2A | 23181 | RNAseq | -0.5655 | 0.0001 | |
| SRP159526 | DIP2A | 23181 | RNAseq | -0.4819 | 0.0061 | |
| SRP193095 | DIP2A | 23181 | RNAseq | -0.0651 | 0.6091 | |
| SRP219564 | DIP2A | 23181 | RNAseq | -0.2578 | 0.4946 | |
| TCGA | DIP2A | 23181 | RNAseq | -0.1575 | 0.0039 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DIP2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DIP2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DIP2A | 23181 | 3 | 9 | 18 | |
| GSE20123 | DIP2A | 23181 | 3 | 9 | 18 | |
| GSE43470 | DIP2A | 23181 | 0 | 14 | 29 | |
| GSE46452 | DIP2A | 23181 | 1 | 21 | 37 | |
| GSE47630 | DIP2A | 23181 | 6 | 17 | 17 | |
| GSE54993 | DIP2A | 23181 | 8 | 1 | 61 | |
| GSE54994 | DIP2A | 23181 | 5 | 8 | 40 | |
| GSE60625 | DIP2A | 23181 | 0 | 0 | 11 | |
| GSE74703 | DIP2A | 23181 | 0 | 10 | 26 | |
| GSE74704 | DIP2A | 23181 | 1 | 5 | 14 | |
| TCGA | DIP2A | 23181 | 10 | 37 | 49 |
Total number of gains: 37; Total number of losses: 131; Total Number of normals: 320.
Somatic mutations of DIP2A:
Generating mutation plots.
Highly correlated genes for DIP2A:
Showing top 20/255 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DIP2A | DDX59 | 0.891566 | 5 | 0 | 5 |
| DIP2A | SLC35E1 | 0.891242 | 10 | 0 | 10 |
| DIP2A | ZNF611 | 0.862152 | 9 | 0 | 8 |
| DIP2A | FBXW12 | 0.857954 | 10 | 0 | 9 |
| DIP2A | ZNF721 | 0.857282 | 11 | 0 | 10 |
| DIP2A | SLC22A3 | 0.856072 | 5 | 0 | 5 |
| DIP2A | CMBL | 0.846213 | 5 | 0 | 5 |
| DIP2A | OCIAD1 | 0.843593 | 3 | 0 | 3 |
| DIP2A | ZC3H7B | 0.831614 | 8 | 0 | 7 |
| DIP2A | UACA | 0.827254 | 4 | 0 | 4 |
| DIP2A | UBXN2A | 0.823588 | 5 | 0 | 5 |
| DIP2A | DBT | 0.815816 | 11 | 0 | 10 |
| DIP2A | FAM161B | 0.804503 | 6 | 0 | 6 |
| DIP2A | NPHP3 | 0.803703 | 3 | 0 | 3 |
| DIP2A | CHD1 | 0.790031 | 3 | 0 | 3 |
| DIP2A | FUT8-AS1 | 0.787701 | 4 | 0 | 4 |
| DIP2A | SLC25A16 | 0.775723 | 9 | 0 | 8 |
| DIP2A | TRMT10B | 0.772471 | 6 | 0 | 6 |
| DIP2A | SSBP3-AS1 | 0.752683 | 5 | 0 | 5 |
| DIP2A | IL6R | 0.752221 | 3 | 0 | 3 |
For details and further investigation, click here
