| Full name: F-box and WD repeat domain containing 12 | Alias Symbol: Fbw12 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 285231 | HGNC ID: HGNC:20729 | Ensembl Gene: ENSG00000164049 | OMIM ID: 609075 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXW12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXW12 | 285231 | 215600_x_at | 0.2103 | 0.8117 | |
| GSE20347 | FBXW12 | 285231 | 215600_x_at | 0.4755 | 0.0316 | |
| GSE23400 | FBXW12 | 285231 | 215600_x_at | 0.0379 | 0.6875 | |
| GSE26886 | FBXW12 | 285231 | 215600_x_at | 0.5728 | 0.0167 | |
| GSE29001 | FBXW12 | 285231 | 215600_x_at | 0.2540 | 0.2004 | |
| GSE38129 | FBXW12 | 285231 | 215600_x_at | 0.2031 | 0.4314 | |
| GSE45670 | FBXW12 | 285231 | 215600_x_at | 0.2254 | 0.0773 | |
| GSE53622 | FBXW12 | 285231 | 53531 | -0.2970 | 0.0001 | |
| GSE53624 | FBXW12 | 285231 | 53531 | -0.3380 | 0.0003 | |
| GSE63941 | FBXW12 | 285231 | 215600_x_at | -0.1699 | 0.5379 | |
| GSE77861 | FBXW12 | 285231 | 215600_x_at | 0.5429 | 0.1052 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXW12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXW12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXW12 | 285231 | 0 | 18 | 12 | |
| GSE20123 | FBXW12 | 285231 | 0 | 19 | 11 | |
| GSE43470 | FBXW12 | 285231 | 0 | 19 | 24 | |
| GSE46452 | FBXW12 | 285231 | 2 | 17 | 40 | |
| GSE47630 | FBXW12 | 285231 | 1 | 24 | 15 | |
| GSE54993 | FBXW12 | 285231 | 6 | 2 | 62 | |
| GSE54994 | FBXW12 | 285231 | 0 | 36 | 17 | |
| GSE60625 | FBXW12 | 285231 | 5 | 0 | 6 | |
| GSE74703 | FBXW12 | 285231 | 0 | 15 | 21 | |
| GSE74704 | FBXW12 | 285231 | 0 | 12 | 8 | |
| TCGA | FBXW12 | 285231 | 0 | 77 | 19 |
Total number of gains: 14; Total number of losses: 239; Total Number of normals: 235.
Somatic mutations of FBXW12:
Generating mutation plots.
Highly correlated genes for FBXW12:
Showing top 20/264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXW12 | SLC35E1 | 0.934392 | 9 | 0 | 9 |
| FBXW12 | PGF | 0.922101 | 9 | 0 | 9 |
| FBXW12 | ALMS1 | 0.918136 | 7 | 0 | 7 |
| FBXW12 | ZC3H7B | 0.914515 | 6 | 0 | 6 |
| FBXW12 | SLC22A3 | 0.906518 | 5 | 0 | 5 |
| FBXW12 | CMBL | 0.902963 | 5 | 0 | 5 |
| FBXW12 | ZNF160 | 0.885102 | 10 | 0 | 10 |
| FBXW12 | ZNF721 | 0.884556 | 10 | 0 | 9 |
| FBXW12 | FUT8-AS1 | 0.865145 | 4 | 0 | 4 |
| FBXW12 | DIP2A | 0.857954 | 10 | 0 | 9 |
| FBXW12 | ZNF611 | 0.849646 | 9 | 0 | 8 |
| FBXW12 | ARHGEF1 | 0.815393 | 5 | 0 | 5 |
| FBXW12 | UACA | 0.813075 | 4 | 0 | 4 |
| FBXW12 | ANKRD10-IT1 | 0.796984 | 9 | 0 | 8 |
| FBXW12 | FAM161B | 0.794194 | 5 | 0 | 5 |
| FBXW12 | TNRC6C-AS1 | 0.77801 | 5 | 0 | 5 |
| FBXW12 | SH2B2 | 0.752694 | 8 | 0 | 8 |
| FBXW12 | SSBP3-AS1 | 0.750092 | 5 | 0 | 5 |
| FBXW12 | MAGI1 | 0.737939 | 4 | 0 | 3 |
| FBXW12 | TRMT10B | 0.733864 | 5 | 0 | 4 |
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