ZC3H7B

 

Full name: zinc finger CCCH-type containing 7B Alias Symbol: RoXaN|FLJ13787|DKFZp434K0920|KIAA1031
Type: protein-coding gene Cytoband: 22q13.2
Entrez ID: 23264 HGNC ID: HGNC:30869 Ensembl Gene: ENSG00000100403 OMIM ID: 618206
Drug and gene relationship at DGIdb

 

Expression of ZC3H7B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZC3H7B 23264 213323_s_at 0.5253 0.0498
GSE20347 ZC3H7B 23264 206169_x_at 0.4815 0.1035
GSE23400 ZC3H7B 23264 213323_s_at 0.2146 0.0000
GSE26886 ZC3H7B 23264 206169_x_at 0.5509 0.0270
GSE29001 ZC3H7B 23264 206169_x_at 0.4411 0.2219
GSE38129 ZC3H7B 23264 206169_x_at 0.2399 0.3757
GSE45670 ZC3H7B 23264 206169_x_at 0.3392 0.0254
GSE53622 ZC3H7B 23264 89963 0.0872 0.4450
GSE53624 ZC3H7B 23264 89963 0.1711 0.0195
GSE63941 ZC3H7B 23264 205877_s_at -1.1999 0.0011
GSE77861 ZC3H7B 23264 206169_x_at 0.0763 0.8396
GSE97050 ZC3H7B 23264 A_23_P218807 -0.5638 0.0794
SRP007169 ZC3H7B 23264 RNAseq 0.4436 0.2378
SRP008496 ZC3H7B 23264 RNAseq 0.4546 0.0307
SRP064894 ZC3H7B 23264 RNAseq 0.3486 0.0465
SRP133303 ZC3H7B 23264 RNAseq 0.1761 0.1189
SRP159526 ZC3H7B 23264 RNAseq 0.6684 0.0405
SRP193095 ZC3H7B 23264 RNAseq 0.5254 0.0000
SRP219564 ZC3H7B 23264 RNAseq 0.2970 0.3434
TCGA ZC3H7B 23264 RNAseq -0.0563 0.1816

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by ZC3H7B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZC3H7B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZC3H7B 23264 6 5 19
GSE20123 ZC3H7B 23264 6 4 20
GSE43470 ZC3H7B 23264 5 6 32
GSE46452 ZC3H7B 23264 31 2 26
GSE47630 ZC3H7B 23264 9 4 27
GSE54993 ZC3H7B 23264 3 6 61
GSE54994 ZC3H7B 23264 11 8 34
GSE60625 ZC3H7B 23264 5 0 6
GSE74703 ZC3H7B 23264 5 4 27
GSE74704 ZC3H7B 23264 3 2 15
TCGA ZC3H7B 23264 27 14 55

Total number of gains: 111; Total number of losses: 55; Total Number of normals: 322.  

 

Somatic mutations of ZC3H7B:

 

Generating mutation plots.

 

Highly correlated genes for ZC3H7B:

 

Showing top 20/463 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZC3H7BMZT2B0.938995707
ZC3H7BSLC35E10.915818707
ZC3H7BFBXW120.914515606
ZC3H7BHAUS20.901872707
ZC3H7BCMBL0.883681303
ZC3H7BDDX590.873785404
ZC3H7BSLC22A30.864226303
ZC3H7BZNF7210.848185807
ZC3H7BDIP2A0.831614807
ZC3H7BZNF1600.825137706
ZC3H7BKLHL240.819019807
ZC3H7BC9orf640.816713504
ZC3H7BPRR110.804124706
ZC3H7BZNF6110.793728706
ZC3H7BGLS0.781977303
ZC3H7BUBE3C0.777877303
ZC3H7BNLN0.776774403
ZC3H7BTNRC6C-AS10.771918303
ZC3H7BPODNL10.771496808
ZC3H7BNAV10.768336303

For details and further investigation, click here